Biometrix Technology Inc.

Chuncheon, South Korea

Biometrix Technology Inc.

Chuncheon, South Korea
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Nimse S.B.,Hallym University | Song K.-S.,Biometrix Technology Inc. | Kim J.,Biometrix Technology Inc. | Ta V.-T.,Hallym University | And 2 more authors.
Chemical Communications | Year: 2011

The flaws in the present probe selection methods restrained the development of the DNA chip technology and its applications. The presented generalized probe selection method for the DNA chips elaborates the length of the probe, the melting temperatures, the specificity of the probe, and the position where the probe may bind to the targets. © 2011 The Royal Society of Chemistry.


Sayyed D.R.,Hallym University | Nimse S.B.,Hallym University | Song K.-S.,Biometrix Technology Inc. | Kim T.,Hallym University
Chemical Communications | Year: 2014

The controller DNA technology allows the detection of multiple mutations in a single codon of genomic DNA. In this technology, the controller DNA is used to control the hybridization of target DNAs with the immobilized DNAs. The controller DNA technology is rapid, specific, and cost-effective for the following reasons, (i) final results in 40 min after PCR, (ii) detection and discrimination of the six mutations in a single codon, and (iii) high sensitivity. This journal is © the Partner Organisations 2014.


Nguyen V.-T.,Hallym University | Nimse S.B.,Hallym University | Song K.-S.,Biometrix Technology Inc. | Kim J.,Biometrix Technology Inc. | And 3 more authors.
Chemical Communications | Year: 2012

The HPAI 9G DNAChip discriminates the single nucleotide polymorphism of H5N1, H5N1 (K), and H5N3 in a 60:1 ratio. It allows the simultaneous detection of highly pathogenic avian influenza viruses with a signal to background ratio of 200 and 100% target-specific hybridization in 30 min at 25°C. This journal is © The Royal Society of Chemistry 2012.


Nimse S.B.,Hallym University | Kim T.,Biometrix Technology Inc.
Chemical Society Reviews | Year: 2013

The functionalized calixarene derivatives exhibit remarkable properties towards organic and bioorganic molecules. However, the ability of calixarene derivatives to form stable complexes with biomolecules allows them to be applied for the development of biosensors and in the field of biology, biotechnology, and drug discovery. The applications of the functionalized calixarenes are summarized in this review, and an outlook for the future developments is discussed. A brief survey (of the last 10 years) on their biological application in various fields is also considered (199 references).


Song K.-S.,Biometrix Technology Inc. | Balasaheb Nimse S.,Hallym University | Kim J.,Hallym University | Kim J.,Biometrix Technology Inc. | And 3 more authors.
Chemical Communications | Year: 2011

We introduce the phenomenon of molecular recognition to immobilize oligonucleotides on AMCA slides for the production of 9G DNAChips. Facile and efficient method for the immobilization of the oligonucleotides appended with consecutive nine guanine bases is described. The 9G DNAChips shows more than 90% hybridization efficiency at 25°C in 30 min. © 2011 The Royal Society of Chemistry.


Song K.-S.,Biometrix Technology Inc. | Nimse S.B.,Hallym University | Kim J.,Biometrix Technology Inc. | Sayyed D.R.,Hallym University | Kim T.,Hallym University
Chemical Communications | Year: 2013

The high SNP discrimination ratio of 3601, 100% target-specific hybridization at 25 °C, detection limit of 101 copies, and differentiation of 101 to 107 copies of the PCR product of high-risk HPV genotypes in clinical samples ensure the application of the 9G membrane in a convenient platform for DNA genotyping.© The Royal Society of Chemistry 2013.


The present invention relates to novel iminecalixarene derivatives, method of preparation thereof, and self-assembled monolayer prepared by the method, fixing method of oligo-DNA by using the self-assembled monolayer, and oligo-DNA chip prepared by the method. Also, the present invention relates to novel aminocalixarene derivatives, method of preparation thereof, and self-assembled monolayer prepared by the method, fixing method of oligo-DNA wherein the oligo-DNA is voluntarily fixed by molecular recognition on said self-assembled monolayer in a liquid phase, and oligo-DNA chip prepared by the method.


The present invention relates to iminecalixarene derivatives, method of preparation thereof, and self-assembled monolayer prepared by the method, fixing method of oligo-DNA by using the self-assembled monolayer, and oligo-DNA chip prepared by the method.Also, the present invention relates to aminocalixarene derivatives, method of preparation thereof, and self-assembled monolayer prepared by the method, fixing method of oligo-DNA wherein the oligo-DNA is voluntarily fixed by molecular recognition on said self-assembled monolayer in a liquid phase, and oligo-DNA chip prepared by the method.


The present invention relates to a) an oligo-DNA chip prepared by fixing an oligo-DNA, wherein at least 7 consecutive guanine bases are attached, on a self-assembled monolayer solid substrate, prepared by attaching an aminocalixarene derivative to a substrate, through multi-molecular refongition, and b) a method for preparing the oligo-DNA chip.


Patent
Chabiotech Co. and Biometrix Technology Inc. | Date: 2010-12-08

The present invention relates to a DNA chip for detecting or typing human papilloma virus (HPV), which comprises (a) a solid substrate of which the surface is coated with a calixarene derivative and (b) a probe hybridizable with the HPV nudeotide sequence which is fixed on the solid substrate. The prove comprises (i) a hybridization site for hybridizing the probe with the HPV nucleotide sequence and (ii) a fixation site containing at least two guanines. Since the DNA chip for HPV genotyping is configured in a strip, the application of the sample to be analyzed and analysis of the results are easy. In addition, the disclosed DNA chip can perform a quantitative analysis of HPV in the sample besides the HPV genotyping.

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