Bioiberica SA

Zaragoza, Spain

Bioiberica SA

Zaragoza, Spain

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Patent
Bioiberica S.A. and Progenika Biopharma S.A. | Date: 2014-01-30

A method for predicting the severity or progression of OA in a human subject, comprising: determining the identity of at least one allele at each of at least 4 positions of single nucleotide polymorphism (SNPs) selected from the group consisting of: rs2206593, rs10465850, rs780094, rs1374281, rs1143634, rs2073508, rs2243250, rs4720262, rs917760, rs7838918, rs12009, rs730720, rs874692, rs893953, rs1799750, rs10845493, rs11054704, rs7986347, rs1802536, rs10519263, rs7342880, rs16947882 and rs10413815, and one or more SNPs in linkage disequilibrium at a level of at least R^(2)0.8 therewith, as well as products, in particular systems and kits for use in such a method.


Patent
Bioiberica S.A. and Progenika Biopharma S.A. | Date: 2011-09-19

A method for predicting risk of joint dysplasia, osteoarthritis and/or a condition that is secondary to joint dysplasia in a mammalian subject of the order Carnivora, the method comprising: (a) determining the genotype of said subject in respect of one or more genetic polymorphisms and/or alterations, such as polymorphisms in the CHST3 gene; and (b) providing a prediction of said risk based on said genotype. Products for use in such a method and related methods of determining propensity of a subject to respond to therapy and of selective breeding, are also disclosed.


Use of aminosugars and chondrocytes for the treatment of cartilage and osteochondral defects and lesions The present invention relates to the use of compositions comprising an aminosugar in combination with chondrocytes, and a biocompatible support matrix for the treatment of cartilage, and osteochondral defects or lesions.


Patent
Bioiberica S.A. | Date: 2016-04-20

The present invention relates to a method for preparing a cartilage product comprising a protein hydrolysate with a degree of hydrolysis comprised between 0.5% and 3.0%, at least one glycosaminoglycan and at least one growth factor. The present invention also relates to the cartilage product obtainable through said method. Said cartilage product is useful in the treatment or prevention of wounds, ulcers, burns, psoriasis, osteoarthritis, synovitis, osteoporosis, osteopenia, diseases of the tendons and ligaments, periodontal diseases, signs of skin aging, the harmful effects of ultraviolet radiation exposure or stretch marks.


The present invention relates to a composition comprising hyaluronic acid and dermatan sulphate for use in the treatment or prevention of overweight, obesity, insulin resistance, type 2 diabetes, fatty liver or dyslipidemia or for use in reducing food intake, inducing the feeling of satiety, reducing appetite, reducing body weight, preventing weight gain, reducing body fat, reducing fat formation, reducing blood cholesterol, maintaining normal blood cholesterol levels, reducing blood triglycerides, maintaining normal blood triglyceride levels or increasing insulin sensitivity. The composition can further contain collagen hydrolysate. The composition can be in the form of a pharmaceutical composition, a food, a functional food, a medical food or a food supplement.


Patent
Bioiberica S.A. | Date: 2016-11-23

The present invention refers to a process for preparing an animal brain extract. It also refers to the brain extract obtainable according to said process and to the use thereof as a medicine, in particular for the prevention and/or treatment of neurodegenerative diseases and disorders of the central nervous system. It also refers to compositions comprising this extract and to its use for preparing these compositions.


Patent
Bioiberica S.A. | Date: 2012-04-16

The present invention relates to a method for preparing a cartilage product comprising a protein hydrolysate with a degree of hydrolysis comprised between 0.5% and 3.0%, at least one glycosaminoglycan and at least one growth factor. The present invention also relates to the cartilage product obtainable through said method. Said cartilage product is useful in the treatment or prevention of wounds, ulcers, burns, psoriasis, osteoarthritis, synovitis, osteoporosis, osteopenia, diseases of the tendons and ligaments, periodontal diseases, signs of skin aging, the harmful effects of ultraviolet radiation exposure or stretch marks.


Patent
Bioiberica S.A. | Date: 2015-06-12

The present invention is related to the use of compositions comprising an enzymatic hydrolysate of animal cartilage protein, at least one organic acid from an alcoholic fermentation, and water, as attractant for flies of the species Drosophila suzukii. Preferably, the animal cartilage is bovine and/or porcine cartilage and the organic acid from an alcoholic fermentation is wine vinegar, apple cider vinegar, white vinegar or rice vinegar.


Patent
Bioiberica S.A. | Date: 2011-03-30

Pharmaceutical composition for the treatment of osteoarthritis The present invention relates to pharmaceutical compositions comprising chondroitin sulphate and an amino sugar, wherein the amino sugar is selected from the group consisting of mannosamine, a mannosamine derivative and mixtures thereof. The mannosamine derivative is preferably N-acetylmannosamine. The pharmaceutical compositions may further comprise glucosamine. Said compositions are disclosed for use as a medicament. In particular, said compositions are useful in the treatment or prevention of degenerative joint diseases, preferably of osteoarthritis, in the treatment or prevention of tendon or ligament diseases, disorders or injuries and of immune system diseases, preferably of rheumatoid arthritis.


Patent
Bioiberica S.A. | Date: 2012-07-04

The present invention relates novel phosphoramidates of monosaccharides of formula (I), wherein R^(1) is a monosaccharide group selected from A and B; R^(2), R^(3), R^(4), R^(5), R^(6), R^(7), R^(8), R^(9), R^(10), R^(11), R^(12), R^(13), R^(14), R^(15), R^(16) and X are as defined herein. Preferably X is -O-. The present invention also provides processes for the production of compounds of formula (I), pharmaceutical compositions comprising these compounds, as well as to the use thereof in medical therapy, preferably in the treatment of osteoarthritis.R^(1) is selected from A and B,

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