Bioengineering R and nter Kragujevac

Kragujevac, Serbia

Bioengineering R and nter Kragujevac

Kragujevac, Serbia
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Cirkovic B.,University of Kragujevac | Isailovic V.,Bioengineering R and nter Kragujevac | Milosevic Z.,Bioengineering R and nter Kragujevac | Radulovic J.,University of Kragujevac | And 6 more authors.
Journal of the Serbian Society for Computational Mechanics | Year: 2012

High-gradient magnetic separation (HGMS) has attracted considerable attention in recent time, both experimentally and theoretically. It has established itself as a powerful technique for the manipulation of particles with magnetic properties. In the present study, analytical and numerical analysis of magnetic separation of cardiomyocytes (CMs) is presented. These enriched cells can be used for therapeutic or tissue engineering applications where no ?labeling? method is accepted. Calculation of applied magnetic force for these particles that can be rendered as paramagnetic inside column was performed in order to clarify the effect of magnetic field gradient on the accumulation possibility of these particles. Numerical solutions of 2D fluid-structure finite element methods are compared with semi-analytical results for combination of magnetic field strength and average flow.


Nikolic M.,University of Kragujevac | Nikolic M.,Bioengineering R and nter Kragujevac | Isailovic V.,University of Kragujevac | Isailovic V.,Bioengineering R and nter Kragujevac | And 12 more authors.
Journal of the Serbian Society for Computational Mechanics | Year: 2014

The cochlea is the most important part of the hearing system, due to the fact that it receives sound in the form of vibrations and converts these vibrations into nerve impulses in the organ of Corti that sends information about sounds to the brain. Functioning of the cochlea components and behavior is still not investigated completely because of its complex structure. Human live cochlea is placed in almost inaccessible place. Because of that it is hard to collect experimental measurement. Cochlea works as an electro-mechanical system and it is important to investigate both electrical and mechanical behavior of the cochlea in order to improve treatment of hearing disorders. This study presents a mechanical model of the uncoiled cochlea using full 3D 8-noded finite elements, as well the electro-mechanical 1D state-space model of the cochlea. The results obtained from these two cochlea models show good matching with Greenwood function and properly simulate the behavior of the cochlea.

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