BMJ case reports | Year: 2013
Dental implants treatment have become a common modality of treatment nowadays for the replacement of missing tooth/teeth, but there have been failures due to a number of reasons; one of the rare problems is the fracture of the dental implants fixture. It is of prime importance to understand the type/system of the implant to be placed in a site and the amount and direction of occlusal forces incurred after the loading of prosthesis.
Agarwal S.,Teerthanker Mahaveer Medical College and Research Center |
Agarwal A.,Teerthanker Mahaveer Medical College and Research Center |
Khanna A.,Institute of Medical science |
Journal of Human Reproductive Sciences | Year: 2015
CONTEXT: In majority of couples experiencing recurrent pregnancy loss (RPL), etiology is still unknown. Two genetic factors have been suggested to underlie miscarriage in a subset of patients, namely skewed X chromosome inactivation in females and Y chromosome microdeletions in their partners. In males, microdeletions of the Y chromosome are known to cause spermatogenetic failure and male infertility. AIMS: The aim of the study was to find out the role of Y chromosome microdeletion in male partners of couples experiencing RPL. SETTINGS AND DESIGN: University hospital and genetic laboratory. Prospective case-control study. SUBJECTS AND METHODS: 59 couples with a history of RPL and 20 fertile controls (FC) with no miscarriage were included in the study. The study subjects were divided into male partners of RPL couples with abnormal semen parameters (AS) (n = 8), and couples with normal semen parameters (NS) (n = 51). Fertile controls with normal semen parameters were (FC) (n = 20). Y chromosome microdeletion was performed on 40 male partners of RPL and 20 FC. STATISTICAL ANALYSIS USED: Chi-square test. P <0.05 were considered statistically significant. RESULTS: 13 of the 40 RPL cases showed deletion in three azoospermia factor loci on the long arm of Y chromosome. The P value was significant with Y chromosome microdeletion in RPL cases as compared to 20 FC where no Y chromosome microdeletion was present. CONCLUSIONS: Y chromosome microdeletion may be an important hidden cause of recurrent pregnancy miscarriage and can be offered to couples with the undiagnosed cause of miscarriage. © 2015 Journal of Human Reproductive Sciences | Published by Wolters Kluwer - Medknow.
Agarwal M.,BHU |
Sharma A.,Banasthali Vidyapeeth
Journal of Health Management | Year: 2011
The study was conducted with the aim of investigating the effects of perception of the hospital workplace factors on the job satisfaction and psychological well-being of a sample of paramedical health care employees (N = 200) from a medical college (teaching) hospital and public (non-teaching) government-run hospitals. Statistical analysis of the data revealed that despite significant differences in perceived work-place factors, the reported levels of psychological well-being and job satisfaction of the participants were nearly similar in the two types of public hospitals. Stepwise regression analysis of the data revealed that the organization's structure-related factors, co-ordination and work autonomy were significantly predictive of job satisfaction and psychological well-being of health care employees, while the process-related workplace factors, participative decision making and intra-professional relations, emerged as significant predictors of psychological well-being and job satisfaction in both types of hospitals. Results have significant implications for public hospitals which are currently facing competition from the state-of-the-art health care technology being introduced by private hospitals, and are therefore under pressure for retention of skilled health care employees. © 2011 SAGE Publications.
Nepal Medical College journal : NMCJ | Year: 2010
Esthesioneuroblastoma (olfactory neuroblastoma) is an uncommon neuroectodermal tumor. Its biological activity ranges from indolent growth to local recurrence and rapid widespread metastasis. Treatment options consist of surgical resection followed by radiation therapy for primary lesions and the addition of chemotherapy for advanced, recurrent, or metastatic lesions. Patients often present with nasal obstruction, rhinorrhea, recurrent epistaxis, hyposmia, or anosmia. We report a case of esthesioneuroblastoma involving bilateral nasal cavity leading to bilateral nasal obstruction, epistaxis and proptosis of the right eye associated with decreased visual acquity on that eye and loss of smell. A diffuse nontender, 6x6 cms swelling with illdefined margins was seen over the nasal bridge, extending superiorly to glabella and laterally to right maxillary region. X-ray PNS showed soft tissue mass in the nasal cavity with destruction of nasal septum, intense periosteal reaction with destruction of right maxillary wall and extension to right orbit. CT scan of paranasal sinuses showed 8.5 x 4.9 x 7.8 cms irregularly marginated heterogeneous iso- to hyper dense soft tissue mass lesion with extensive adjacent bony destruction and spiculated periosteal reaction involving bilateral nasal cavity and anterior cranial fossa. Biopsy from right nasal mass showed neuroblastoma. The patient received radiotherapy and chemotherapy. The modified Kadish staging system, lymph node status, treatment modality, and age are useful predictors of survival in patients who present with esthesioneuroblastoma. Excellent outcomes for esthesioneuroblastoma are achievable. Long-term follow-up is necessary because of the extended interval for recurrent disease; unlike most sinonasal malignancies, surgical salvage is possible.
Journal of the Geological Society of India | Year: 2014
Since the Precambrian time the Narmada-Son Lineament (NSL) is a zone of weakness and both the northern and southern portions of Narmada-Son Lineament experienced vertical block movements. It is established by the earlier workers that NSL is a sub-crustal feature which is responsible for the deposition and folding of the Vindhyans (Meso- Neoproterozoic) and Gondwanas (Permo-Carboniferous-lower Cretaceous). Recent tectonic activity in the Narmada- Son region is evidenced by high heat flow thermal activity, sulphur springs and seismically the Narmada-Son Lineament region is known to be a significantly disturbed zone. The present study area is the part of Narmada-Son Lineament zone. The drainage geomorphology of the area between Kanahar and Rihand rivers (tributaries of the tectonically controlled Son river) around Renukoot area have been studied aiming to understand active tectonics of the region, integrating detailed analysis of landforms and drainages. Various geomorphic features present in the study area such as incision of valley, aligned drainage, aligned valleys, linear valleys, offset channels, offset ridges and fault scarps demonstrate that the area is undergoing active deformation. © 2014, Geological Society of India.