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Ramakrishna B.S.,Christian Medical College | Makharia G.K.,All India Institute of Medical Sciences | Ahuja V.,All India Institute of Medical Sciences | Ghoshal U.C.,Sanjay Gandhi Post Graduate Institute of Medical Sciences | And 23 more authors.
Indian Journal of Gastroenterology | Year: 2015

In 2012, the Indian Society of Gastroenterology’s Task Force on Inflammatory Bowel Diseases undertook an exercise to produce consensus statements on Crohn’s disease (CD). This consensus, produced through a modified Delphi process, reflects our current recommendations for the diagnosis and management of CD in India. The consensus statements are intended to serve as a reference point for teaching, clinical practice, and research in India. © 2015, Indian Society of Gastroenterology. Source


Makharia G.K.,All India Institute of Medical Sciences | Ramakrishna B.S.,Christian Medical College | Abraham P.,nduja National Hospital And Medical Research Center | Choudhuri G.,Sanjay Gandhi Post Graduate Institute of Medical Sciences | And 19 more authors.
Indian Journal of Gastroenterology | Year: 2012

Introduction: Inflammatory bowel disease (IBD), both ulcerative colitis (UC) and Crohn's disease (CD), once thought to be uncommon, is now seen commonly in India. The Indian Society of Gastroenterology (ISG) Task Force on IBD decided to collate data on the clinical spectrum of IBD currently prevailing in India. Methods: An open call to members of ISG was given through publication of a proforma questionnaire in the Indian Journal of Gastroenterology and the web portal of ISG. The proforma contained questions related with demographic features, family history, risk factors, clinical manifestations and characteristics, course of disease, and pattern of treatment of IBD. Results: Of 1,255 filled questionnaires received, 96 were rejected and 1,159 (92. 3 %) were analyzed. This comprised data on 745 (64.3 %) patients with UC, 409 (35.3 %) with CD, and 5 with indeterminate colitis. The median duration of illness was longer in patients with CD (48 months) compared to those with UC (24 months) (p = 0.002). More than one half of patients (UC 51.6 %, CD 56.9 %) had one or more extraintestinal symptoms. A definite family history of IBD was present in 2.9 % (UC 2.3 % and CD 4.6 %; p = 0.12). The extent of disease in UC was pancolitis 42.8 %, left-sided colitis 38.8 %, and proctitis alone in 18.3 %. The extent of disease involvement in CD was both small and large intestine in 39.6 %, colon alone in 31.4 % and small intestine alone in 28.9 %. Stricturing and fistulizing disease were noted in 18.8 % and 4.4 % of patients with CD respectively. Chronic continuous and intermittent disease course were present in 35.5 % and 47.2 % of UC patients respectively, and in 23.1 % and 68.8 % of CD patients. Four percent of patients with UC had undergone colectomy, while 15.2 % of patients with CD underwent surgical intervention. Conclusions: The present survey provides a reasonable picture of the demographic features and clinical manifestations of Indian patients with IBD, their risk factors, course of disease, and the treatment given to them. © 2012 Indian Society of Gastroenterology. Source


Ramakrishna B.S.,Christian Medical College | Makharia G.K.,All India Institute of Medical Sciences | Abraham P.,nduja National Hospital And Medical Research Center | Ghoshal U.C.,Sanjay Gandhi Post Graduate Institute of Medical Sciences | And 25 more authors.
Indian Journal of Gastroenterology | Year: 2012

In 2010, the Indian Society of Gastroenterology's Task Force on Inflammatory Bowel Diseases undertook an exercise to produce consensus statements on ulcerative colitis. This consensus, produced through a modified Delphi process, reflects our current understanding of the definition, diagnostic work up, treatment and complications of ulcerative colitis. The consensus statements are intended to serve as a reference point for teaching, clinical practice, and research in India. © 2012 Indian Society of Gastroenterology. Source

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