Beytepe Military Hospital Ankara

Ankara, Turkey

Beytepe Military Hospital Ankara

Ankara, Turkey
SEARCH FILTERS
Time filter
Source Type

PubMed | GATA Haydarpasa Training Hospital Istanbul, Beytepe Military Hospital Ankara and Ankara Mevki Military Hospital Ankara
Type: Journal Article | Journal: International journal of clinical and experimental medicine | Year: 2014

Immature teratoma is quite uncommon older women, particular in postmenopausal period. Only a few cases of postmenopausal immature teratoma of the genital tract have been reported. This report describes a postmenopausal aggressive pelvic immature teratoma case with a grave course despite treatment. A 67-year-old woman being in menopause for the past 16 years was diagnosed with immature teratoma in the pelvic cavity. The mass was removed completely and hysterectomy plus bilateral salpingo-oophorectomy was done. Histopathological diagnosis was grade 2 immature teratoma. The patient had a grave course with recurrences despite therapy and died within one year after initial diagnosis. In teratomas diagnosed over 45 years of age, the possibility of malignant teratoma should also be borne in mind.


PubMed | GATA Haydarpasa Training Hospital Istanbul and Beytepe Military Hospital Ankara
Type: Journal Article | Journal: International journal of clinical and experimental medicine | Year: 2014

The aim of this study was to investigate the factors associated with serum levels of several tumor markers in a group of patients operated for uterine myoma. One hundred thirty-seven female patients operated for uterine myoma were included. Serum samples were examined for CA 125, CA 19-9, CA 15-3, carcinoembryonic antigen (CEA) and alpha-fetoprotein (AFP) levels as part of routine workup. Pathological and morphological characteristics of the patients were retrieved from medical records. The mean age was 46.7 8.8 years (range, 22-85 y). Abnormally high levels of CA 125, CA 19-9, CA 15-3, CEA, and AFP were found in 19.7%, 6.6%, 5.1%, 3.7%, and 1.5% of the patients, respectively. Patients with additional adenomyosis and patients with at least one large myoma ( 5 cm diameter) had significantly higher levels of CA 125. Multivariate analysis identified coexistence of adenomyosis (OR 7.7 [95% CI, 2.6-23.0], p < 0.001) and presence of at least one large myoma (OR 5.6 [1.4-22.8], p = 0.016) as independent predictors of abnormally high CA 125 levels. CA 125 levels are affected by the tumor size and coexistence of adenomyosis in uterine leiomyomas. Indirect mechanisms caused by large myoma size such as peritoneal irritation may be responsible for CA 125 elevations.


PubMed | GATA Haydarpasa Training Hospital Istanbul and Beytepe Military Hospital Ankara
Type: Journal Article | Journal: International journal of clinical and experimental medicine | Year: 2014

A thorough evaluation of the uterine cavity is frequently required in gynecology practice. The aim of this study was to compare the diagnostic values of transvaginal ultrasound examination and hysteroscopy in detecting uterine abnormalities in a group of patients within a range of menopausal status and symptomatology. This study included 285 patients admitted with complaints of abnormal uterine bleeding, postmenopausal bleeding, lower abdominal pain, abnormal vaginal discharge or for a routine gynecological examination. All patients had available transvaginal ultrasonography and hysteroscopy data for evaluation. A biopsy was obtained from all patients during the hysteroscopy session. Sensitivity, specificity, positive predictive value, negative predictive value and likelihood ratio were calculated for both methods and compared, considering the histopathological diagnosis as the gold standard. The mean age of the patients was 49.512.9 years (range, 24-89 y). Majority of the patients admitted for abnormal uterine bleeding (n=198, 69.4%). For the diagnosis of polyps of any size, hysteroscopy had better sensitivity (p<0.001), however, specificities did not differ (p=1.0). On the other hand, hysteroscopy did not have a sensitivity advantage over TVU in diagnosing polyps greater than 1 cm (p=0.077), although this time hysteroscopy had better specificity (p<0.001). Combined approach did not offer diagnostic advantage for any of the specific pathologies. Although TVU represents a practical approach for the initial evaluation of uterine pathologies, hysteroscopy seems to offer better diagnostic value for uterine pathologies in general, and uterine polyps in particular.

Loading Beytepe Military Hospital Ankara collaborators
Loading Beytepe Military Hospital Ankara collaborators