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Saint David’s, United Kingdom

Brenke R.,Berlin | Brenke R.,Kortexmed Institute For Medizinische Bildung | Siems W.,Kortexmed Institute For Medizinische Bildung
Schweizerische Zeitschrift fur GanzheitsMedizin | Year: 2013

The aspects of Kneipp therapy and of classical natural medicine are characterized by a wide spectrum of effects and efficacy. We suggest that the basic mechanisms of such classical types of therapy are elementary and unique being based on ubiquitous substances and biochemical reactions. In this regard, we investigated the reactive oxygen species (ROS), lipid peroxidation (LPO) products, and antioxidative protective mechanisms. The balance between prooxidative and antioxidative mechanisms-characterizing the so-called oxidative stress-exerts high impact on the status of health, disease, wellbeing, and fitness. The review on all five parts of Kneipp therapy-hydrotherapy, phytotherapy, nutritional therapy, exercise therapy, and regulatory therapy-supplies distinct arguments for improved coping with oxidative stress by means of all forms of Kneipp therapy. It is clearly demonstrated that the reduced formation of free oxygen radicals and/or the increased removal of these potentially toxic substances is a combining element in natural medicine. © 2013 S. Karger GmbH, Freiburg. Source


Santos S.,Institute For Allgemeinmedizin | Lessing C.,Berlin | Schrappe M.,Cologne | Vollmar H.C.,Institute For Allgemeinmedizin Und Familienmedizin | And 3 more authors.
Gesundheitswesen | Year: 2015

Aim of the Study: In order to minimise the risk of patient misidentification in clinical settings, the German Coalition for Patient Safety published recommendations for safety patient identification in 2008. The aim of this study was to develop, implement and evaluate a theoretical framework of knowledge transfer. The purpose of the framework was to enhance hospital staff’s ability to apply the recommendations for safe patient identification in the daily routine of patient care. Method: A data bank-based research and literature review have been conducted. Research topics were: knowledge transfer, change management and implementation science. Within the application of the concept group interviews were held with hospital staff and the interview material was evaluated using content analysis. On this basis a tailored multifaceted implementation strategy has been developed and applied in 8 hospital wards of 4 hospitals belonging to a communal hospital concern. The evaluation of the developed knowledge transfer concept was conducted 4 weeks after the concept application with a written questionnaire. Results: The developed framework concept of knowledge translation consisted of 4 phases built on top of each other: initiation phase; analysis phase; implementation phase; evaluation phase. The multifaceted implementation strategy included 3 interventions: a poster, a computer-based training and a guideline for team meetings. The survey yielded responses from 56 individuals: 96% declared that they know about the existence of the recommendations for safe patient identification; 86% said that they know about the content of the recommendations; 91% have striven to apply the recommendations in the daily routine of patient care; 71% stated that the recommendations for safe patient identification have become integral part in the daily routine of patient care. To become aware of the recommendations and its content the respondents have used on average 2.3 interventions, however the effect of the CBS was relatively small. Conclusion: The developed theoretical framework concept for knowledge transfer provides a way to integrate the recommendations for safe patient identification in the daily routine of patient care and to counteract risk factors promoting misidentification. Therefore a multifaceted implementation strategy is promising. Copyright ©, Georg Thieme Verlag KG. All rights reserved. Source


Kolditz M.,TU Dresden | Ewig S.,Thoraxzentrum Ruhrgebiet | Klapdor B.,Thoraxzentrum Ruhrgebiet | Schutte H.,Charite - Medical University of Berlin | And 47 more authors.
Thorax | Year: 2015

Background Early organ dysfunction determines the prognosis of community-acquired pneumonia (CAP), and recognition of CAP as a medical emergency has been advocated. Objective To characterise patients with 'emergency CAP' and evaluate predictors for very early organ failure or death. Methods 3427 prospectively enrolled patients of the CAPNETZ cohort were included. Emergency CAP was defined as requirement for mechanical ventilation or vasopressor support (MV/VS) or death within 72 h and 7 days after hospital admission, respectively. To determine independent predictors, multivariate Cox regression was employed. The ATS/IDSA 2007 minor criteria were evaluated for prediction of emergency CAP in patients without immediate need of MV/VS. Results 140 (4%) and 173 (5%) patients presented with emergency CAP within 3 and 7 days, respectively. Hospital mortality of patients presenting without immediate need of MV/VS was highest. Independent predictors of emergency CAP were the presence of focal chest signs, home oxygen therapy, multilobar infiltrates, altered mental status and altered vital signs (hypotension, raised respiratory or heart rate, hypothermia). The ATS/IDSA 2007 minor criteria showed a high sensitivity and negative predictive value, whereas the positive predictive value was low. Reduction to 6 minor criteria did not alter accuracy. Conclusions Emergency CAP is a rare but prognostic relevant condition, mortality is highest in patients presenting without immediate need of MV/VS. Vital sign abnormalities and parameters indicating acute organ dysfunction are independent predictors, and the ATS/IDSA 2007 minor criteria show a high negative predictive value. © 2015 BMJ Publishing Group Ltd & British Thoracic Society. Source


Kurtz O.,Berlin | Barthelmes J.,Berlin | Ruther R.,Berlin | Danker M.,Berlin | And 2 more authors.
Galvanotechnik | Year: 2010

Where corrosion-, tarnish- and wear-resistant surfaces are required in electronic or electrical applications, gold alloy coatings continue to be the default solution. Such coatings must additionally be solderable and bondable. The preferred alloying metal is usually cobalt. Using a quartz microbalance and FIB, electrodeposition behaviour at various current densities and under differing flow conditions was studied using a weakly acidic solution with from 2 to 20 g per litre. Current efficiency varied during the deposition and was primarily a function of electrolyte composition and current density, ranging from 20% to more than 50%. Source

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