Berea, KY, United States
Berea, KY, United States

Berea College is a liberal arts work college in Berea , in the U.S. state of Kentucky, founded in 1855. Berea College is distinctive among post-secondary institutions for providing free education to students and for having been the first college in the Southern United States to be coeducational and racially integrated. Berea College charges no tuition; every admitted student is provided the equivalent of a four-year, full-tuition scholarship .Berea offers Bachelor's degrees in 32 majors. It has a full-participation work-study program where students are required to work at least 10 hours per week in campus and service jobs in over 130 departments. Berea's primary service region is Southern Appalachia, but students come from 46 states in the United States and 58 other countries, with approximately one in three students an ethnic minority or international. Wikipedia.

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Messina T.C.,Berea College
Methods in Molecular Biology | Year: 2017

Molecular dynamics of complex biological and chemical systems is possible using personal computers due to increased computer performance and improved software design. Here we describe molecular dynamics methods using Not Another Molecular Dynamics (NAMD) and Visual Molecular Dynamics (VMD) programs that aid in understanding the structural effects a mutation has on a protein. We describe in silico methods for site-specific mutation to standard and phosphorylated amino acids. Molecular dynamics equilibrations are used to provide a means for measuring structural fluctuations. These fluctuations assist in defining a distance coordinate, or reaction coordinate, that is relevant to the function of the protein. Adaptive biasing force molecular dynamics are then demonstrated to evaluate the energy landscape, or potential of mean force, along the chosen reaction coordinate. The potential of mean force identifies variations of the predominant structures among mutants that may affect function. © Springer Science+Business Media New York 2017.

Amarnath V.,Vanderbilt University | Amarnath K.,Vanderbilt University | Avance J.,Berea College | Stec D.F.,Vanderbilt University | Voziyan P.,Vanderbilt University
Chemical Research in Toxicology | Year: 2015

Pyridoxamine (PM) is a prospective drug for the treatment of diabetic complications. In order to make zwitterionic PM more lipophilic and improve its tissue distribution, PM derivatives containing medium length alkyl groups on the hydroxymethyl side chain were prepared. The synthesis of these alkylpyridoxamines (alkyl-PMs) starting from pyridoxine offers high yields and is amenable to bulk preparations. Interestingly, alkyl-PMs were found to react with methylglyoxal (MGO), a major toxic product of glucose metabolism and autoxidation, several orders of magnitude faster than PM. This suggests the formation of nonionic pyrido-1,3-oxazine as the key step in the reaction of PM with MGO. Since the primary target of MGO in proteins is the guanidine side chain of arginine, alkyl-PMs were shown to be more effective than PM in reducing the modification of N-α-benzoylarginine by MGO. Alkyl-PMs in the presence of MGO also protected the enzymatic activity of lysozyme that contains several arginine residues next to its active site. Alkyl-PMs can be expected to trap MGO and other toxic 1,2-carbonyl compounds more effectively than PM, especially in lipophilic tissue environments, thus protecting macromolecules from functional damage. This suggests potential therapeutic uses for alkyl-PMs in diabetes and other diseases characterized by the elevated levels of toxic dicarbonyl compounds. (Chemical Equation Presented). © 2015 American Chemical Society.

News Article | February 16, 2017

BEREA, KY, February 16, 2017-- Irene H. Lamb has been included in Marquis Who's Who. As in all Marquis Who's Who biographical volumes, individuals profiled are selected on the basis of current reference value. Factors such as position, noteworthy accomplishments, visibility, and prominence in a field are all taken into account during the selection process.Deeply committed to the medical community, Ms. Lamb is noted for her involvement with medical research at a time when that was uncommon for women. She is credited with helping to establish the first coronary care center in the United States, among many other professional accomplishments. In recognition of her contributions to medicine and science, Ms. Lamb has been featured in a wide range of honors publications, including Who's Who in America, Who's Who of American Women, Who's Who in the South and Southwest, Who's Who in Medicine and Healthcare, Who's Who in Science and Engineering, and Who's Who in the World. In addition, she was selected for inclusion in the 32nd and 33rd editions of Who's Who in Finance and Industry, as well as the 4th and 5th editions of Who's Who in American Nursing.A Registered Nurse residing in Kentucky, Ms. Lamb began a medical career upon receiving a diploma in nursing from the Kentucky Baptist Hospital. She had frequently attended Berea College working towards a biology degree and completed additional training at California State University in Los Angeles. During this time, Ms. Lamb assisted the University of Southern California and Los Angeles County Medical Center as a staff nurse and researcher. She has held various additional roles throughout the course of her career, including charge nurse and head nurse of acute medicine in a wide range of departments and medical centers, such as the medical intensive care unit, surgical intensive care unit and emergency room. In 1969, Ms. Lamb became the nurse manager of the clinical research center at the University of Southern California and Los Angeles County Medical Center. She remained in this position for five years before joining the Stanford University School of Medicine as a senior research nurse in the field of cardiology. In 1989, Ms. Lamb rose to the rank of director of clinical research with the San Diego Cardiac Center.Ms. Lamb has held a keen interest in stroke research since the turn of the century. From 1997 to 2002, she served as the senior of clinical research and manager of the stroke program with the University of Kentucky College of Medicine, located in Lexington. In addition, she was a member of the board of directors with the Kentucky Stroke Association from 1998 to 2000. An accomplished author, Ms. Lamb has contributed articles to professional journals and chapters to medical books.About Marquis Who's Who :Since 1899, when A. N. Marquis printed the First Edition of Who's Who in America , Marquis Who's Who has chronicled the lives of the most accomplished individuals and innovators from every significant field of endeavor, including politics, business, medicine, law, education, art, religion and entertainment. Today, Who's Who in America remains an essential biographical source for thousands of researchers, journalists, librarians and executive search firms around the world. Marquis now publishes many Who's Who titles, including Who's Who in America , Who's Who in the World , Who's Who in American Law , Who's Who in Medicine and Healthcare , Who's Who in Science and Engineering , and Who's Who in Asia . Marquis publications may be visited at the official Marquis Who's Who website at

Khoshnevisan B.,University of Tehran | Rafiee S.,University of Tehran | Omid M.,University of Tehran | Mousazadeh H.,University of Tehran | Clark S.,Berea College
Journal of Cleaner Production | Year: 2014

This study was carried out in Isfahan province, Iran, to assess the environmental impact of greenhouse cucumber and tomato production using life-cycle assessment (LCA) methodology. In this study a cradle-to-farm-gate approach using data from greenhouse operators and two distinct functional units, one mass-based and the other land-based, were selected to analyze the impact categories. Data for production of inputs were taken from EcoInvent ®2.0 database, and SimaPro software was employed for analysis. Ten impact categories including Abiotic Depletion potential, Acidification potential, Eutrophication potential, Global Warming potential for time horizon 100 years, Ozone Depletion potential, Human Toxicity potential, Freshwater and Marine Aquatic Ecotoxicity potential, Terrestrial Ecotoxicity potential, and Photochemical Oxidation potential were selected based on the CML 2 baseline 2000 V2/world, 1990/characterization method. In addition, adaptive neuro-fuzzy inference system (ANFIS) was employed to predict the environmental impact of both crops on the basis of input materials. The results indicated that greenhouse tomato production had a lower environmental impact than cucumber due to less total energy input and correspondingly lower environmental burdens in all impact categories. Almost all impact categories were dominated by natural gas, electricity and nylon (as cover of greenhouses). Furthermore, the results revealed that ANFIS was capable of forecasting the environmental indices of greenhouse production with a high degree of accuracy and minimal error. © 2013 Elsevier Ltd. All rights reserved.

Malanushenko A.,Montana State University | Yusuf M.H.,Berea College | Longcope D.W.,Montana State University
Astrophysical Journal | Year: 2011

In the present work, we study the evolution of magnetic helicity in the solar corona. We compare the rate of change of a quantity related to the magnetic helicity in the corona to the flux of magnetic helicity through the photosphere and find that the two rates are similar. This gives observational evidence that helicity flux across the photosphere is indeed what drives helicity changes in the solar corona during emergence. For the purposes of estimating coronal helicity, we neither assume a strictly linear force-free field nor attempt to construct a nonlinear force-free field. For each coronal loop evident in extreme ultraviolet, we find a best-matching line of a linear force-free field and allow the twist parameter α to be different for each line. This method was introduced and its applicability discussed in Malanushenko et al. The object of this study is emerging and rapidly rotating AR 9004 over about 80 hr. As a proxy for coronal helicity, we use the quantity 〈αi Li /2〉 averaged over many reconstructed lines of magnetic field. We argue that it is approximately proportional to the "flux-normalized" helicity H/Φ2, where H is the helicity and Φ is the total enclosed magnetic flux of the active region. The time rate of change of such a quantity in the corona is found to be about 0.021 radhr-1, which is comparable with the estimates for the same region obtained using other methods, which estimated the flux of normalized helicity to be about 0.016 radhr-1. © 2011. The American Astronomical Society. All rights reserved.

Agency: NSF | Branch: Standard Grant | Program: | Phase: | Award Amount: 208.48K | Year: 2011

While spending on higher education represents a substantial portion of government expenditures and while the importance of the early portion of individuals working lives has been well-recognized, policymakers are currently faced with the task of designing effective policies with only an incomplete understanding of many important issues related to the college and early post-college periods. This project combines the collection of state-of-the-art survey (and administrative) data with innovative analyses to provide new evidence about many of these issues.

What takes place during the college portion of ones lifetime has traditionally been somewhat of a black box in which students are observed entering with certain observable background characteristics and are eventually seen leaving having made a variety of decisions and having realized a number of related outcomes. Similarly, what takes place during the early portion of ones post-college lifetime has also traditionally been somewhat mysterious. While recent research has stressed the importance of looking inside the college and early post-college black boxes, evidence about the college period and the early post-college period has remained at best incomplete. This is the case, in large part, because standard longitudinal surveys are often not well-positioned to provide data that allow issues of interest to be studied at their most fundamental levels.

This reality motivates the survey component of the current project which, building on previous research funded by the National Science Foundation, involves the continued collection of a longitudinal survey (the Berea Panel Study) that is unequaled in its depth and detail. The survey efforts pay careful attention to recent advances in survey methodology, and, at the culmination of the three-year project period, two cohorts of college students will have been followed very closely from the time they entered college until past the age of thirty.

From a feasibility standpoint, the importance of collecting person-specific information that is substantially more detailed than what is available from other existing data sources necessitates the focus on a single institution (Berea College). However, while this influences the exact extent to which the conclusions can be generalized, it seems reasonable to believe that the basic elements that go into the decisions of students in the collected sample will be generally similar to those that go into the decisions of individuals from similar backgrounds who enroll at other schools. Thus, the innovative nature of the survey collection efforts has the potential to provide policymakers with a much improved understanding of the workings of the higher education process and the early post-college period.

At its most general level, the goal of the data collection in the project is to allow analyses which provide new understandings of how earnings/wages are determined at different stages of the early post-college period. This, in turn, requires one to understand:
1) what determines a persons stock of human capital (i.e., his skills and abilities) at the time he/she leaves college and at different points in the early post-college period?
2) how do individuals make decisions that determine how much and what type of human capital is accumulated?
Then the need for an ambitious data collection effort comes from the fact that virtually all decisions and outcomes in the college and early post-college periods are of relevance for understanding these two questions.

Many important decisions and outcomes that ultimately influence earnings take place during college. While much previous research has related decisions and outcomes during college to a set of observable background characteristics of students, it is much more difficult to understand the underlying processes by which decisions are made or outcomes are produced. This is the case, in large part, because a particular decision or outcome may be influenced by a rather large and potentially complicated set of factors. As such, an important feature of the data collection is that, paying close attention to economic theory, the survey instruments were designed to collect information about comprehensive sets of factors that could influence a variety of college decisions/outcomes. These decisions/outcomes include those related to: educational attainment/drop-out, college major, college grade performance, study effort, peer effects, and social networks.

Other important decisions and outcomes that potentially influence earnings after individuals leave college and enter the workforce, include decisions/outcomes related to:
1) job search and job changing behavior, 2) marriage and fertility, 3) time away from the labor market, 4) the type of jobs held or skills accumulated while on the job. The depth of the Berea Panel Study data allows an examination of these decisions/outcomes, in general, and for different subgroups of the population. For example, of particular importance will be the ability of the survey to provide new evidence about the underlying reasons for differences in earnings by gender.

In addition to the substantive contribution of providing new evidence about the college and early post-college periods, the project will likely motivate/guide future data collection and analyses involving nationally representative samples. Generally, this is the case because the project illustrates the value of collecting detailed longitudinal data with the analyses of very specific models and issues in mind. As one of many specific examples of the broader impacts of the project?s survey efforts, while the interest in expectations data has increased substantially in recent years, much remains unknown about the full potential of using such data in economic contexts.

The Berea Panel Study was perhaps the first longitudinal survey to have a strong focus on the elicitation of expectations data, and the analyses in the project will examine a variety of potential uses for this type of data that would not be possible to examine using other data sources. Moreover, because the longitudinal collection of expectations data allows one to directly measure revisions to expectations, the project will might provide the best direct evidence about the importance of learning per se in determining outcomes in education and the early portion of ones working life.

Agency: NSF | Branch: Standard Grant | Program: | Phase: | Award Amount: 96.60K | Year: 2010

NON-TECHNICAL DESCRIPTION: Funding from NSF will support several studies over a three year period in an undergraduate setting. These studies will explore new ways of synthesizing and examining half-metals. Half metals are conductors when the carrier electrons are one spin orientation, but are insulators to electrons of the opposite orientation. This research will be assisted by the development of new matrices to be used in the matrix assisted laser desorption ionization (MALDI) technique in search of some parent anions that have not been previously observed. Half-metals have shown promise to play an important role in the development of future electronic devices. The proposed new method involves the use of laser vaporization of the half-metal constituents in a controlled condensation chamber in an inert atmosphere. As laser ablation has proven to be an effective technique of generating fullerenes, endohedral metallofullerenes, and similar caged molecules, a search for new caged molecular species will be undertaken with the help of this support. In addition to the possible synthesis of new materials, these studies offer the opportunities of hands-on experience for physics and chemistry undergraduate students, which they hope will serve to increase the students interest in physics, chemistry, and material science in an integrative approach of teaching and research.

TECHNICAL DETAILS: In the well-established Fe(1-x)Co(x)Si compounds there are specific ranges of x for which the material is considered to be a half-metal. The appearance of half metallicity is accompanied by ferromagnetism in these compounds. The laser vaporization technique will be used to synthesize the family of half metals Fe(1-x)Co(x)Z (where Z = Si, Ge, and Sn) with the goal of exploring the effect of the size of the Z-site elements by substituting elements from the same column of the periodic table on the properties of this family. Fe(1-x)Co(x)(Ge, Sn) compounds have not yet been observed. The laser ablation technique will be utilized in search of caged molecules that have been calculated to be energetically stable such as C12B24N24. Sublimation techniques that accompany the laser ablation in a heated zone gradient will be used to separate the various mixed metal compounds where Raman spectroscopy under nitrogen and computations can be employed for structural determination at the University of Tennessee. Furthermore, various matrices will be investigated to observe the parent anions of hydrogenated fullerenes. Undergraduate students will have hands-on experience in new technologies such as laser ablation and time-of-flight mass spectrometry.

Agency: NSF | Branch: Standard Grant | Program: | Phase: | Award Amount: 296.39K | Year: 2013

This WIDER project is transforming the introductory STEM courses at Berea College into high-­engagement, active learning environments following the SCALE-­UP model that has shown to be successful in physics and other STEM disciplines. Introductory courses in biology, chemistry, physics, and computer science are being targeted. Baseline data described the enrollments and instructional modes in the targeted courses. These courses are being further enhanced by the inclusion of undergraduate Teaching Associates from the Berea College Labor Program (work study), who are acting as peer instructors in the classroom and enabling the program to maintain a student-­teacher ratio of 10-1 that is supporting student learning.

The underlying change strategy for this project can be described as environmental/emergent. It is capitalizing on a faculty culture of reflective teaching, while moving towards a shared vision for first year STEM courses. This project is creating lasting, transformative change by: 1) supporting a faculty-­led initiative to implement substantive changes in introductory STEM classrooms, 2) by deepening knowledge about evidence-­based practice among the faculty, and by 3)improving student learning and retention in first year STEM courses.

This project capitalizes on several strengths of Berea College, including its well­-established Labor Program, a collegial and collaborative environment for teaching, and the facultys commitment to providing a high-­quality education to underserved students from Appalachia and beyond. Because of its historic mission to serve groups traditionally under-­represented in higher education and STEM, Berea College is ideally placed to gauge the effectiveness of this model on the retention and success of economically disadvantaged students in STEM disciplines. In addition, as a member of the Work Colleges Consortium, Berea is serving as a national exemplar for the implementation of studio-­based introductory STEM courses using undergraduate Teaching Associates to maintain a low student-­teacher ratio.

Agency: NSF | Branch: Standard Grant | Program: | Phase: IUSE | Award Amount: 81.64K | Year: 2016

The Promoting a Growth Mindset Using Automated Feedback project will develop and evaluate a new strategy for generating automated feedback on programming assignments that will provide a more welcoming experience for students, recognizing the effort they put in as they work on solutions. The goal of the project will be to promote the adoption of a growth mindset - a belief that ones abilities will improve with practice and hard work, which is associated with a range of improved educational outcomes. This strategy will encompass four key ideas: a measurement approach for assessing student effort; the use of non-points-based bonuses to reward effort and recognize hard work for positive reinforcement; heat maps of student code to highlight where bugs are located; and a strategy for clearly identifying the top priority for students to tackle in order to make progress.

During the first year of the project, all three schools will collect baseline data using existing conventional feedback approaches. The new feedback intervention will be evaluated in years two and three of the project. Quantitative and qualitative data will be collected and analyzed to examine changes in performance and students behavior. A mixed-method data collection plan will triangulate the quantitative and qualitative data with the review of literature and the researchers direct experience in teaching these courses to reach conclusions regarding research questions of the study and provide the framework for the design of a scalable and replicable intervention to improve students performance in the programming projects.

News Article | December 1, 2016

Less than a month after the election, fires ripped through eastern Tennessee, killing seven, and forcing thousands of evacuations. Much of the Southeast is experiencing extreme drought conditions; Tennesseans fled burning homes and hotels, many with just what they could carry. In the midst of disaster, many in Appalachia feel forgotten. Jason Howard, a professor at Berea College in Kentucky, noted the sentiment in a pointed op-ed: Unfortunately, this lack of attention is all too familiar to the residents of Appalachia, who have historically been ignored or misrepresented in the national consciousness. News coverage has focused on economic poverty rather than cultural riches, a handful of feuds rather than strong family ties. … Even amid the disaster in Gatlinburg, some commenters on social media have perpetuated hateful stereotypes: That the moonshine stills of the poor, ignorant hillbillies have accidentally set the mountains ablaze, or that Tennesseans, who largely voted for Mr. Trump, are getting their just deserts.

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