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Beijing, China

Beijing Normal University , colloqiually known as 北师大 or Beishida, is a public research university located in Beijing with strong emphasis on basic disciplines of humanities and science. It is one of the oldest and most prestigious universities in China.A normal school referred to an institution that aimed to train school teachers in the early twentieth century, and this terminology is preserved in the official names of such institutions in China. Wikipedia.

Wang K.,Beijing Normal University | Dickinson R.E.,University of Texas at Austin
Reviews of Geophysics | Year: 2012

This review surveys the basic theories, observational methods, satellite algorithms, and land surface models for terrestrial evapotranspiration, E (or E, i.e., latent heat flux), including a long-term variability and trends perspective. The basic theories used to estimate E are the Monin-Obukhov similarity theory (MOST), the Bowen ratio method, and the Penman-Monteith equation. The latter two theoretical expressions combine MOST with surface energy balance. Estimates of E can differ substantially between these three approaches because of their use of different input data. Surface and satellite-based measurement systems can provide accurate estimates of diurnal, daily, and annual variability of E. But their estimation of longer time variability is largely not established. A reasonable estimate of E as a global mean can be obtained from a surface water budget method, but its regional distribution is still rather uncertain. Current land surface models provide widely different ratios of the transpiration by vegetation to total E. This source of uncertainty therefore limits the capability of models to provide the sensitivities of E to precipitation deficits and land cover change. © 2012 by the American Geophysical Union.

Fan Z.,Beijing Normal University
Physical Review D - Particles, Fields, Gravitation and Cosmology | Year: 2013

We investigate holographic fermions in general asymptotically scaling geometries with hyperscaling violation exponent θ, which is a natural generalization of fermions in Lifshitz space-time. We prove that the retarded Green functions in this background satisfy the angle-resolved photoemission spectroscopy sum rules by introducing a dynamical source on a UV brane for zero density fermionic systems. The big difference from the Lifshitz case is that the mass of probe fermions decoupled from the UV theory and thus has no longer been restricted by the unitarity bound. We also study finite density fermions at finite temperature, with dynamical exponent z=2. We find that the dispersion relation is linear, but the logarithm of the spectral function is not linearly related to the logarithm of k=k-kF, independent of charge q and θ. Furthermore, we show that, with the increasing of charge, new branches of Fermi surfaces emerge and tend to gather together to form a shell-like structure when the charge reaches some critical value beyond which a wide band pattern appears in the momentum-charge plane. However, all sharp peaks will be smoothed out when θ increases, no matter how much large the charge is. © 2013 American Physical Society.

Deng F.-G.,Beijing Normal University
Physical Review A - Atomic, Molecular, and Optical Physics | Year: 2012

We propose an optimal nonlocal entanglement concentration protocol (ECP) for multiphoton systems in a partially entangled pure state, resorting to the projection measurement on an additional photon. One party in quantum communication first performs a parity-check measurement on her photon in an N-photon system and an additional photon, and then she projects the additional photon into an orthogonal Hilbert space for dividing the original N-photon systems into two groups. In the first group, the N parties will obtain a subset of N-photon systems in a maximally entangled state. In the second group, they will obtain some less-entangled N-photon systems which are the resource for the entanglement concentration in the next round. By iterating the entanglement concentration process several times, the present ECP has the maximal success probability, which is just equivalent to the entanglement of the partially entangled state. That is, this ECP is an optimal one. © 2012 American Physical Society.

Cui M.,Beijing Normal University
Current Medicinal Chemistry | Year: 2014

The deposition of β-amyloid (Aβ) plaques in the parenchymal and cortical brain is accepted as the main pathological hallmark of Alzheimer's disease (AD). According to the amyloid cascade hypothesis, the Aβ deposition in the brain appears to be a good diagnostic biomarker for AD and may also be a good predictive biomarker of this disease. Molecular imaging of Aβ plaques in the brain with positron emission tomography (PET), single photon emission computed tomography (SPECT) or molecular optical imaging represents a promising approach to the early diagnosis of AD and monitoring the effectiveness of novel therapies for this devastating disease. Our review focuses on the past and recent knowledge in this field with respect to small organic molecules that have been utilized for the development of Aβ imaging probes. © 2014 Bentham Science Publishers.

Patel D.J.,Sloan Kettering Cancer Center | Wang Z.,Sloan Kettering Cancer Center | Wang Z.,Beijing Normal University
Annual Review of Biochemistry | Year: 2013

This review focuses on a structure-based analysis of histone posttranslational modification (PTM) readout, where the PTMs serve as docking sites for reader modules as part of larger complexes displaying chromatin modifier and remodeling activities, with the capacity to alter chromatin architecture and templated processes. Individual topics addressed include the diversity of reader-binding pocket architectures and common principles underlying readout of methyl-lysine and methyl-arginine marks, their unmodified counterparts, as well as acetyl-lysine and phosphoserine marks. The review also discusses the impact of multivalent readout of combinations of PTMs localized at specific genomic sites by linked binding modules on processes ranging from gene transcription to repair. Additional topics include cross talk between histone PTMs, histone mimics, epigenetic-based diseases, and drug-based therapeutic intervention. The review ends by highlighting new initiatives and advances, as well as future challenges, toward the promise of enhancing our structural and mechanistic understanding of the readout of histone PTMs at the nucleosomal level. © 2013 by Annual Reviews. All rights reserved.

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