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Shui Y.,Capital Medical | Tao W.,Capital Medical | Huang D.,Central South University | Li Y.,Beijing Institute of Functional Neurosurgery | Fan B.,Quail Surgical & Pain Management Center
Pain Physician | Year: 2012

Background: Neuropathic pain is a relatively common outcome of Lyme disease. Pain management options for these patients have been limited to pharmaceutical treatments. Objective: We present a case of chronic pain following Lyme disease treated successfully using spinal cord stimulation (SCS). Study Design: Case report. Setting: Pain management clinic. Methods: A 62-year-old patient presented with a 5-year history of bilateral foot pain following Lyme disease that failed to respond to medication and physical therapy. The patient was treated by a trial of SCS at the clinic and then implanted with a spinal cord stimulator. The Visual Analog Scale (VAS) assessed pain before and after SCS. Results: The patient reported significant pain relief and improved foot function. The 10 point VAS score was reduced from 8-10 to 1-3. Limitations: Single case report. Conclusion: Spinal cord stimulation may be an effective option for relieving chronic pain originating from Lyme disease. Source

Duanyu N.,Capital Medical University | Yongjie L.,Beijing Institute of Functional Neurosurgery | Guojun Z.,Capital Medical University | Lixin C.,Capital Medical University | Liang Q.,Capital Medical University
Journal of Clinical Neuroscience | Year: 2010

We report a patient with medically intractable musicogenic epilepsy (ME) who was treated with surgery. Using the non-invasive methods of ictal and interictal electroencephalography (EEG), MRI, interictal single photon emission computed tomography and clinical manifestations, we first localized the musicogenic seizures (MS). The ictal onset zone was then further localized using intracranial EEG to the middle part of the left superior temporal gyrus. Surgical resection of the epileptogenic zone was then performed. The patient had two seizures within 2 weeks post-operatively, but has then had no seizures during the following year (Engel class II). The results suggest that patients who have medically intractable ME combined with unilateral ictal onset zones should be considered for the surgical treatment of epilepsy. © 2009 Elsevier Ltd. All rights reserved. Source

Li J.,Capital Medical University | Zhang Y.,Capital Medical University | Zhu H.,Capital Medical University | Li Y.,Beijing Institute of Functional Neurosurgery
Journal of Clinical Neuroscience | Year: 2012

The reliability of intra-operative abnormal muscle response (AMR) monitoring as an indicator of post-operative outcome in patients with hemifacial spasm (HFS) is under debate. The primary aim of this study was to evaluate the correlation between intra-operative AMR changes and long-term post-operative outcome. We monitored intra-operative AMR during microvascular decompression (MVD) in consecutive patients with HFS (n = 104). Patients in this study were divided into two groups based on whether their AMR disappeared or persisted following MVD. Ninety patients were followed-up, and the mean duration from surgery to final follow-up examination was 3.7 years. Fourteen patients were lost to follow-up. AMR disappeared during surgery for 80 patients; of these, 74 achieved complete resolution of HFS, five had persistent HFS, and one patient developed a recurrence of HFS. Of the 10 patients with persistent AMR despite effective MVD, eight patients achieved complete resolution, one patient had persistent HFS, and one developed recurrent HFS. The long-term clinical outcome of HFS after MVD did not significantly correlate with intra-operative AMR changes (p = 0.791). Therefore, we suggest that intra-operative AMR monitoring may not be a reliable indicator of long-term post-operative outcome for HFS. © 2011 Elsevier Ltd. All rights reserved. Source

Dong S.,Beijing Institute of Functional Neurosurgery | Zhang X.,Beijing Institute of Functional Neurosurgery | Li J.,Beijing Institute of Functional Neurosurgery | Li Y.,Beijing Institute of Functional Neurosurgery
Acta Neurochirurgica | Year: 2014

A 30-year-old man underwent bilateral GPi DBS for refractory TS. His tics and obsessive-compulsive symptoms were significantly improved after chronic stimulation. At 22 months postoperatively, the implantable pulse generator had to be removed because of an infection in the infraclavicular pouch. However, we observed an unexpected effectiveness at follow-up more than 4 years after stopping the stimulation. This is the first case report of TS that showed a favorable long-term outcome after cessation of chronic GPi DBS. © 2014 Springer-Verlag. Source

Dong S.,Beijing Institute of Functional Neurosurgery | Dong S.,Capital Medical University | Zhuang P.,Beijing Institute of Functional Neurosurgery | Zhuang P.,Capital Medical University | And 6 more authors.
Journal of International Medical Research | Year: 2012

Tourette's syndrome is a complex neuropsychiatric disorder, characterized by tics. Bilateral globus pallidus internus (GPi) deep brain stimulation (DBS) has been considered to be an effective treatment for refractory Tourette's syndrome. Postoperative outcomes are described after 12 months' follow-up in a 41-year-old male patient and a 22-year-old male patient with Tourette's syndrome, both of whom underwent unilateral electrode implantations into the right GPi for DBS. These patients were diagnosed with Tourette's syndrome in childhood and, despite long-term therapy with a range of antipsychotic medications, continued to experience disabling tics in adulthood. Improvements in tic severity of 58.5% and 53.1% were observed at 12 months in the older and younger patient, respectively; improvements were determined by the Yale Global Tic Severity Scale. Both patients also experienced reductions in tic frequency and reported improvements in their health-related quality of life. Improvements in tics were similar to previous reports involving patients who underwent bilateral GPi DBS. These cases suggest that unilateral DBS of the right GPi is effective and might be a viable surgical choice for some patients with Tourette's syndrome. © SAGE Publications Ltd 2012. Source

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