Xu L.-R.,Institute of AIDS |
Yang X.-P.,CAS Zhengzhou Research Institute |
Guo H.-J.,Institute of AIDS |
Tu J.-W.,Traditional Chinese Medicine of Hubei Province |
And 6 more authors.
Zhongguo Zhongyao Zazhi | Year: 2013
Objective: Study on quality of life of asymptomatic HIV infected persons with traditional Chinese medical, which can provide the clinical basis for improving the quality of life. Method: This study applied a randomized, double-blind, and placeb-parallel control designed method to select 1200 persons in the asymptomatic period of HIV infection as the subjects. The subjects were randomly divided into the treatment group and the control group at the ratio of about 2:1.According to the results of monthly differential diagnosis of TCM, the test group and the control group were given homologue Chinese drugs preparations and model Chinese drugs. The total study period was 18 months. Using PRO scale and the world health organization AIDS determination of quality of life short scale form (WHOQOL-HIV-BREF) to investigate asymptomatic HIV infected persons, according to different times, we calculated the total score and each domain score of quality of life of the treatment group and control group, we did statistical analysis. Result: Form the PRO scale, we can see that the treatment group showed a trend of stability, compared with the control group with significant statistical difference (P<0.05) after 6 months; from the WHOQOL-HIV scale analysis, we can see that compared with before treatment, the quality of life of the treatment group was increased, the difference was significant (P<0.05), but the quality of life of the control quality of life was decreased, the differences was significant (P<0.05). Conclusion: Dialectical therapy of Chinese medicine can significantly improve the patient's quality of life, which can provide the basis for the prevention and control policy formulation and implementation with asymptomatic HIV infected persons.