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Guo Y.,Beihua University
Physica A: Statistical Mechanics and its Applications | Year: 2017

We propose a new stochastic regime switching SIR model driven by Lévy noise. A unique global positive solution is obtained under some appropriate conditions. Moreover, we investigate the asymptotic behavior of the stochastic SIR model with jumps under regime switching. © 2017 Elsevier B.V.

OBJECTIVE: To investigate the application effect of oncolytic herpes simplex virus Once Vex(GM-CSF) and adriamycin in malignant tumor.METHODS: A total of 102 cases of malignant tumor were analyzed retrospectively from April 2013 to April 2015 of Cancer Treatment Center of Affiliated Hospital of Beihua University, and these cases were randomly divided into trial group (n=51) and control group (n=51). The control group was treated with adriamycin and the trial group patients received conditionally replicating adenoviruses on the basis of the control group.The adenovirus proliferation was analyzed via quantitative PCR to investigate the malignant tumor cell inhibitory action in two groups.RESULTS: Treatment group total effective rate (96.1%, 49/51) was significantly higher than the control group (78.4%, 40/51) (χ(2)=7.845, P=0.014). There were statistically significant difference of the killing capability between trial group (86.3%, 44/51) and control group (23.5%, 12/51) (χ(2)=7.859, P=0.013). Tumor shrinkage rate of trial group(76.5%, 39/51) was superior to that of the control group(19.6%, 10/51), the difference was statistically significant (χ(2)=7.654, P=0.019). There was statistically significant difference of the decrease of tumor marker CA125 between trial group (74.5%, 38/51) and control group (23.5%, 12/51) (χ(2)=7.342, P=0.023).CONCLUSION: Once Vex(GM-CSF) can effectively kill the tumor cells in the treatment of malignant tumor, and shrink the tumor significantly.

Ding T.,Beihua University
RISTI - Revista Iberica de Sistemas e Tecnologias de Informacao | Year: 2016

There are a lot of false news in the network environment. Without an effective recognition and discrimination of false news, individuals may suffer from both spiritual and physical harms, or even be exposed to graver threats socially. Therefore, it is of great significance to analyze the cause to and identification mode of false news in the network environment, as well as to quantify their harmfulness. To this end, we first analyzed the factors and background that allow the generation of false news in the network environment; then, on this basis, we considered the characteristics and features of false news to study on the methods and strategies to recognize false news; afterwards, by discussing the harmfulness of false news and its measurement indicators and referring to fuzzy mathematical theories, we established a fuzzy classification model of the hazard of false news which realized a preliminary quantification of false news harmfulness. Finally, discussion and outlook were included of the propagation of false news in the network environment.

Zhang S.,Beihua University
RISTI - Revista Iberica de Sistemas e Tecnologias de Informacao | Year: 2016

Over the past years, high-quality productions and high-level service strategy have already became the important factors for the auto industry competition. With the development of the computer technology and information technology, especially the launch of the National Information Infrastructure, ITS becomes the important research and development direction of the auto industry. Vehicle Condition Remote Monitoring and Fault Prediction System as the important elements contains practical and profound meaning of the researches. This paper takes the automotive hydraulic brake system as example, first it analyzes the dynamic working process of automotive hydraulic brake system and establishes the whole motor model; then, it improves the model and analyzes the possible factors which influence the model; finally, it analyzes the common fault mode and reasons of automotive hydraulic brake system. On that basis, it ensures the monitoring parameters and methods, laying a good foundation for Vehicle Condition Monitoring and fault prediction.

Wang L.,Beihua University
Proceedings - 2016 9th International Congress on Image and Signal Processing, BioMedical Engineering and Informatics, CISP-BMEI 2016 | Year: 2016

A new algorithm based on the coherent signal-subspace method (CSM) is developed to estimate the angle and range parameters of the wideband near-field linear frequency modulated (LFM) sources. The algorithm decomposed the wideband LFM signals into several narrowband LFM signals, and focused the every narrowband signals to the same reference frequency by the coherent subspace algorithms, and then constructed the MUSIC spectrum function, utilized the peak search method for estimating the bearing and range of wideband LFM near field sources. The algorithm's characteristic is that the noise subspace of the received signal can directly be estimated by the propagator method, and the spectral function can be constructed without the singular value decomposition. So the calculation of the Incoherent Signal-subspace algorithm can be effectively reduced, meanwhile the estimation performance can be kept higher. The computer simulation shows the effectiveness of the developed algorithm. © 2016 IEEE.

Liu Y.B.,Beihua University
Zhonghua nan ke xue = National journal of andrology | Year: 2011

To investigate the expressions of survivin and GRIM-19 in prostatic cancer tissue and their clinical implications. We detected the expressions of survivin and GRIM-19 in the tissues of normal prostate (NP), benign prostate hyperplasia (BPH) and prostate cancer (PCa) using immunohistochemical staining, RT-PCR and Western blot, and processed the data by SPSS12. The positive rates of survivin expression were 6.25% , 18.18% and 90.62% in NP, BPH and PCa (P < 0.01), while those of GRIM-19 were 87.50%, 81.82% and 9.37% , respectively (P < 0.01). Semiquantitative RT-PCR and immunohistochemical staining showed that both survivin mRNA and survivin expressions were highly positive in PCa but negative in NP and BPH. Western blot exhibited that the survivin protein was expressed strongly in PCa but weakly in NP and BPH, while the GRIM-19 protein was expressed just contrariwise (P < 0.01). The expressions of survivin and GRIM-19 may be closely correlated with the pathogenesis of prostate cancer.

To observe the effect of ischemia postconditioning during the first minutes of reperfusion for the myocardial reperfusion injury in ST-segment elevation acute myocardial infarction (STEMI) patients undergoing emergency percutaneous coronary intervention (PCI). STEMI patients undergoing emergency PCI in affiliated hospital of Beihua University between October 2006 and January 2009 were randomly divided into two groups: the control group (n = 34) without any intervention after PTCA, and the postconditioning group (n = 30) with ischemia postconditioning within first minutes of reflow by 3 episodes of 30-second inflation and 30-second deflation with the angioplasty balloon. Reperfusion arrhythmias, CK and CKMB, corrected TIMI frame count (CTFC), wall motion score index (WMSI) and left ventricular ejection fraction (LVEF) by echocardiography were compared between the two groups. MI areas were evaluated with the ECG-54 criteria/32 system and myocardial blush grade (MBG) was measured. The incidence of reperfusion arrhythmias-frequent ventricular premature (26.7% vs. 52.9%) and short array ventricular tachycardia beat (23.3% vs. 58.8%) as well as values of peaks CK [(1162 ± 548) U/L vs. (1732 ± 480) U/L, P < 0.01], CKMB [(165 ± 70) U/L vs. (280 ± 99) U/L, P < 0.01], CTFC (22.23 ± 3.81 vs. 26.97 ± 3.42), WMSI (1.27 ± 0.52 vs. 1.82 ± 0.83), and infarction areas determined by ECG methods (10.60% ± 4.97% vs.14.65% ± 6.88%, all P < 0.05) were all significantly lower in the postconditioning group than in control group while LVEF (0.55 ± 0.08 vs. 0.47 ± 0.10) and MBG (2.27 ± 0.64 vs. 1.47 ± 0.61, all P < 0.05) were significantly higher in the postconditioning group than in control group. Ischemia postconditioning can significantly reduce myocardial reperfusion injury in patients with STEMI.

Zhu H.-Y.,Beihua University
World Transactions on Engineering and Technology Education | Year: 2015

Such outstanding problems as lack of user participation, low resource-sharing and inconvenient retrievals still exist in the construction of digital learning resources in China. Using a questionnaire, the demand and application of current digital learning resources in colleges and universities was analysed, and the problems in the current construction of digital learning resources identified. Based on the analysis and to address the identified problems, a system for the construction of learning resources in a participatory digital library based on Moodle was developed and is presented in this article. © 2015 WIETE.

Li H.,Beihua University
World Transactions on Engineering and Technology Education | Year: 2015

In distance education, students find it hard to come to an institution's school laboratory to complete experiments. The Web virtual laboratory, which is a development of the virtual laboratory, allows virtual experiments in the Internet environment. The research reported in this article developed the basic structural and network features, and operating mode, of the on-line virtual laboratory for distance education based on the Web. The system architecture, building the component library and the design of the human-computer interface as key technologies in the implementation, are presented and discussed in this article. © 2015 WIETE.

Guo S.,Beihua University
Proceedings 2011 International Conference on Mechatronic Science, Electric Engineering and Computer, MEC 2011 | Year: 2011

It is the application of Controller Area Network (CAN) that changed vehicle electrical system wiring and control mode, wiring harness and controller pin count were decreased, so the cost was reduced. The comparative method is applied in this paper base on traditional vehicle circuit and CAN-bus circuit. The result shows CAN-bus not only can improve reliability and control function, but reduced the costs and the car failure rate. © 2011 IEEE.

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