Hu R.,Central Hospital of Bazhong |
Wang Y.-L.,North Sichuan Medical College
Journal of Clinical Rehabilitative Tissue Engineering Research | Year: 2010
OBJECIVE: To explore the material features and biocompatibility of coronary artery stent and related complications following implantation. METHODS: The databases of CNKI and Medline were searched by the first author using key words of "coronary artery stent, material, biocompatibility and complications" both in English and Chinese. Meta analysis or repetitive studies were excluded, and 16 papers were included in this analysis. RESULTS: Stent materials play an important role in reducing inflammatory reaction and restenosis following stent implantation. As a medical material for humans, the features of stent should be meet the requirements of reliable distensibility, mechanical persistence, good flexibility and geometrical stability, possible small diameter, excellent blood compatibility, as well as good corrosion resistance. All of these depended on the mechanical and physical features of materials. Conclusion: The study of drug-coating stent and drug-eluting stent reduced the restenosis rates following implantation, and the biodegradable stent also attracted more attention. When treating coronary heart disease with cardiovascular stent, the complications should be avoided except consideration of the successful rate of reperfusion.