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Ankara, Turkey

Bakar B.,Kirikkale University | Tekkok I.H.,Bayindir Hospital
Turkish Neurosurgery | Year: 2015

The extent of the slice thickness in spinal axial and sagittal magnetic resonance imaging (MRI) is limited. We therefore, propose the idea of using coronal MRI to better delineate lumbar far lateral disc herniations. Six patients with coronal MR images who underwent surgery are presented in this study. Simple 2D vertebral column X-ray and MRI scans were used to diagnose the far lateral herniated disc. Intraoperative findings confirmed our preoperative MRI diagnosis in all patients. Recovery was excellent in all patients. In conclusion, coronal lumbar MRI, a simple and useful technique to reveal the nerve roots in foraminal and/or far lateral (extraforaminal) areas, is a must for accurate diagnosis of foraminal and/or far lateral lumbar disc herniations. Source

Bayar S.A.,Baskent University | Kucukerdonmez C.,Izmir University | Oner O.,Fehime Faik Kocagoz Hospital | Akova Y.A.,Bayindir Hospital
International Ophthalmology | Year: 2014

The aim of this study is to evaluate the efficacy and safety of subconjunctival bevacizumab injection(s) in the treatment of impending recurrent pterygia. Twenty-three eyes of 23 patients who developed impending recurrence after pterygium surgery with conjunctival autografting and were treated with subconjunctival bevacizumab injection(s) (2.5 mg/0.1 mL) were included in the study. Anterior segment photographs were taken prior to and at 1 week, 1, 3 and 6 months after the injection, and at the end of the follow-up period. Image analysis was performed using an image processing and analysis software program. Recurrence rate and complications were recorded. The mean age and follow-up time of the patients were 51.2 ± 6.2 (31-60 years) and 16.8 ± 3.1 (12-22 months), respectively. The average number of injections was 2 ± 0.78 (1-3). Sixteen eyes required re-injection (two injections in nine eyes, three injections in seven eyes), due to progression of vascularization. There were significant differences between size percentage of lesions before injection and at 1 week, 1, 3 and 6 months after the injection (p < 0.05 for all). Corneal recurrence developed in only one patient and no ocular or systemic side-effects of bevacizumab were observed. Repeated injections of bevacizumab may help to prevent the high recurrence rate of residual impending pterygium, due to its adjuvant role in decreasing lesion size, especially in the first year after surgery. © Springer Science+Business Media 2013. Source

Savas Tepe M.,Bayindir Hospital
Gulhane Medical Journal | Year: 2013

Aim: To compare the dysfunction and complication rates of small bore and large bore gastrostomy catheters. Material and Methods: A total of 521 patients (291 males, 230 females, mean age 56 years, range 16-90 years) underwent percutaneous fluoroscopic gastrostomy placement between August 2000 and January 2009. Choice of catheter was based on the preference of the Radiologist. Data was collected retrospectively with institutional review board approval. Radiology reports provided clinical history, indication for gastrostomy, information of the catheter, technical success, and immediate outcome. Post procedural complications and clinical outcomes were obtained. Results: All catheters were placed successfully. 15 patients with anatomic difficulties for G tube placement were discarded from the study. Patients who received large bore and small bore catheters were compared. Patients with larger catheters (18F) had fewer short and long term complications and tube dysfunction compared to patients with smaller bore catheters (14F). Discussion and Conclusions: Patients who received small bore gastrostomy catheters were significantly more prone to tube dysfunction. Large bore catheters should be preferred for fewer complications in short and long term. © Gülhane Askeri Tip Akademisi 2013. Source

Aim: Bronchial artery embolization is known to be effective in the acute control of hemoptysis secondary to cystic fibrosis complication. In this retrospective study 14-year-experience of our clinic with embolization for treatment of hemoptysis in patients with cystic fibrosis is reviewed. The results with coil and polyvinyl alcohol microparticule embolizations are demonstrated. Material and Method: 15 patients (age range 19-54) with cystic fibrosis presented with major or persistent hemoptysis that required 33 embolizations from September 1994 to November 2009. Results: Hemoptysis stopped within a day after embolization in all fifteen patients. There were no major immediate complications within 24 hours for coil only or polyvinyl alcohol microparticule only sessions or the combination of these. Mean survival duration after the first embolization was 58 months (average follow up 72 months; range 3-168 months, including all patients). One patient died, two patients underwent lung transplant during the follow up period. Conclusion: In our retrospective study with 15 patients and 33 embolization sessions which include 9 patients with more than one embolization demonstrated high success rate in short term. Long term results however showed that 9 out of 15 patients (60%) required repeated embolization. © Gülhane Askeri Tip Akademisi 2013. Source

Baudouin C.,Center Hospitalier National dOphtalmologie des Qinze Vingts and Vision Institute | Aragona P.,Messina University | Messmer E.M.,Ludwig Maximilians University of Munich | Tomlinson A.,Glasgow Caledonian University | And 6 more authors.
Ocular Surface | Year: 2013

Dry eye disease (DED), a multifactorial disease of the tears and ocular surface, is common and has a significant impact on quality of life. Reduced aqueous tear flow and/or increased evaporation of the aqueous tear phase leads to tear hyperosmolarity, a key step in the vicious circle of DED pathology. Tear hyperosmolarity gives rise to morphological changes such as apoptosis of cells of the conjunctiva and cornea, and triggers inflammatory cascades that contribute to further cell death, including loss of mucin-producing goblet cells. This exacerbates tear film instability and drives the cycle of events that perpetuate the condition. Traditional approaches to counteracting tear hyperosmolarity in DED include use of hypotonic tear substitutes, which have relatively short persistence in the eye. More recent attempts to counteract tear hyperosmolarity in DED have included osmoprotectants, small organic molecules that are used in many cell types throughout the natural world to restore cell volume and stabilize protein function, allowing adaptation to hyperosmolarity. There is now an expanding pool of clinical data on the efficacy of DED therapies that include osmoprotectants such as erythritol, taurine, trehalose and L-carnitine. Osmoprotectants in DED may directly protect cells against hyperosmolarity and thereby promote exit from the vicious circle of DED physiopathology. © 2013 The Authors. Published by Elsevier Inc. Source

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