Deerfield, IL, United States

Baxter International

www.baxter.com
Deerfield, IL, United States

Baxter International Inc. is an American health care company with headquarters in Deerfield, Illinois. The company primarily focuses on products to treat hemophilia, kidney disease, immune disorders and other chronic and acute medical conditions. Wikipedia.


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Patent
Baxter International and Baxter Healthcare SA | Date: 2017-05-10

The invention relates to a hemodialysis system comprising a blood component portion including a blood pump; a blood cassette (150) operatively connected to the blood pump such that the blood pump can pump blood through the blood cassette (150) when the blood cassette (150) is in fluid communication with a blood source; a dialyzer fluidly connected to the blood cassette (150); a dialysate component portion separate from the blood component portion, the dialysate component portion including a dialysate pump; and a dialysate cassette (10e) separate from the blood cassette (150), the dialysate cassette (10e) operatively connected to the dialysate pump such that the dialysate pump can pump dialysate through the dialysate cassette (10e) when the dialysate cassette (10e) is in fluid communication with the dialysate source, the dialysate cassette being fluidly connected to the dialyzer.


Patent
Baxter International and Baxter Healthcare SA | Date: 2017-02-06

A peritoneal dialysis system includes: a drain container; a drain line placed in fluid communication with the drain container and configured to be placed in fluid communication with a patients peritoneal cavity; a vacuum source configured to apply a pneumatic force to cause used dialysis fluid to flow through the drain line from the patients peritoneal cavity to the drain container; a weight sensor configured to output a weight of used dialysis fluid delivered to the drain container from the patients peritoneal cavity; and a controller configured to: (i) determine an actual flow rate of used dialysis fluid removed from the patients peritoneal cavity based on the output from the weight sensor; (ii) compare the actual flow rate to a desired flow rate; and (iii) adjust the pneumatic force applied by the vacuum source to attempt to match the actual flow rate to the optimal flow rate.


Patent
Baxter International and Baxter Healthcare SA | Date: 2017-05-24

This application discloses devices, articles, and methods useful for producing lyophilized cakes of solutes. The devices and articles provide for a method of freezing liquid solutions of the solute by the top and the bottom of the solution simultaneously and at approximately the same rate. The as frozen solution can then provide a lyophilized cake of the solutes with large and uniform pores.


Patent
Baxter International and Baxter Healthcare SA | Date: 2017-06-07

A method for detecting an access disconnect, the method comprising:placing an acoustic sensor upstream of a venous access site;detecting a first heart beat of a patient;determining a first baseline signal from the first heart beat;sensing a second heart beat of the patient;determining a second baseline signal from the second heart beat;comparing the second baseline signal to the first baseline signal; andsending an alert if the step of comparing indicates that the access disconnect or a leak has occurred.


Patent
Baxter International, Baxter Healthcare Sa and Northwestern University | Date: 2017-03-03

The invention provides methods of immobilizing an active agent to a substrate surface, including the steps of, depositing a primer compound on a substrate, thereby forming a primed substrate, contacting the primed substrate with a solution of a compound including a trihydroxyphenyl group, thereby forming a trihydroxyphenyl-treated primed substrate, and contacting the trihydroxyphenyl-treated primed substrate with a solution of an active agent, thereby immobilizing the active agent on the substrate. Further provided are methods of immobilizing an active agent on a substrate, including the steps of providing a substrate, combining a solution of a compound including a trihydroxyphenyl group with a solution of an active agent, thereby forming a solution of an active agent-trihydroxyphenyl conjugate, and contacting the primed substrate with the solution of the active agent-trihydroxyphenyl conjugate, thereby immobilizing the active agent on the substrate. The invention further provides substrates and medical device or device components with active agents immobilized on the surface thereof.


Patent
Baxter International and Baxter Healthcare Sa | Date: 2017-03-13

A device or system includes a mixer comprising a three-dimensional lattice defining a plurality of tortuous, interconnecting passages therethrough. The mixer is in communication with sources or streams of at least two separate components which, when mixed, form a combined fluid stream. The sources or streams may be, at least initially, on opposite sides of the mixer, or the sources or streams may be on the upstream side of the mixer with an outlet disposed downstream of the mixer. A related method may include providing a mixer comprising a three-dimensional lattice defining a plurality of tortuous, interconnecting passages therethrough, and selecting a material for the mixer based on physical characteristics of said material, said characteristics including a selected one or more of mean flow pore size, thickness and porosity volume.


Patent
Baxter International and Baxter Healthcare SA | Date: 2017-03-09

A renal failure blood therapy system includes a renal failure blood therapy machine, concentration levels for each of a plurality of solutes removed from a patients blood at each of the multiple times, a display device configured to display for selection at least one removed blood solute from the plurality of removed blood solutes, and a device programmed to (i) estimate at least one renal failure blood therapy patient parameter using the determined concentration levels for the at least one selected removed blood solute, (ii) determine a plurality of acceptable renal failure blood therapy treatments that meet a predetermined removed blood solute clearance for the at least one selected removed blood solute using the at least one renal failure blood therapy patient parameter, and (iii) enable selection of at least one of the plurality of acceptable renal failure blood therapy treatments for operation at the renal failure blood therapy machine.


Patent
Baxter International and Baxter Healthcare S.A. | Date: 2017-07-12

A dialysis fluid treatment device (100) for removing urea is described. The device comprises: a first cell (110) comprising an electrodialysis unit (120) having a cathode (122) and two opposing anodes (124, 126); and a second cell (130) comprising a urease compartment (132) and a sorbent compartment (134) and in fluid communication with the first cell (10).


Systems and methods for providing for the automatic instrument-based rapid reprocessing of an intact extracorporeal circuit for use in hemodialysis. The system includes a manifold with connectors for engaging a dialyzer as well as venous and arterial blood lines. The manifold is adapted to be moved from a dialysis machine to a reuse instrument without removing the dialyzer and associated blood lines. The system allows for reprocessing of the extracorporeal circuit wherein prior to the next treatment, there is no residual chemical disinfectant requiring testing, the extracorporeal circuit is pre-primed, the levels in the bubble traps are set, and all of the required quality assurance tests are performed and recorded.


Patent
Baxter International and Baxter Healthcare SA | Date: 2017-04-20

A renal failure therapy machine includes a blood cleaning filter, a dialysis fluid circuit including a balance chamber, the balance chamber including a fresh dialysis fluid compartment configured to send fresh dialysis fluid to the blood cleaning filter and a used dialysis fluid compartment configured to receive used dialysis fluid from the blood cleaning filter, a fresh dialysis fluid line in fluid communication with the fresh dialysis fluid compartment of the balance chamber and the blood cleaning filter, and a flow restrictor in fluid communication with the blood cleaning filter, the flow restrictor configured to cause fresh dialysis fluid delivered from the fresh dialysis fluid compartment, through the fresh dialysis fluid line, to the blood cleaning filter to be pressurized so that a first amount of the fresh dialysis fluid performs convective clearance and a second amount of the fresh dialysis fluid performs diffusive clearance.

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