Matveeva E.L.,Russian University of Cooperation |
Korosteleva V.P.,Russian University of Cooperation |
Papynidi E.K.,Russian University of Cooperation |
Yusupova G.R.,Kazan Bauman State Academy of Veterinary Medicine |
Smolentsev S.Y.,Mari State University
Research Journal of Pharmaceutical, Biological and Chemical Sciences | Year: 2015
The most optimal solution to the problem of mycotoxicosis are preventive measures that inhibit the growth of fungi and mycotoxin formation. It has been shown that the quaternary ammonium compound cause marked ultrastructural changes, showing bactericidal, fungistatic and fungicidal properties with regard to the test microbes and fungi Aspergillus niger.
Smolentsev S.Y.,Mari State University |
Papunidi H.K.,Kazan cooperative institute branch Russian University of cooperation |
Korosteleva V.P.,Kazan cooperative institute branch Russian University of cooperation |
Popovich E.M.,Kazan cooperative institute branch Russian University of cooperation |
Yusupova G.R.,Kazan Bauman State Academy of Veterinary Medicine
Research Journal of Pharmaceutical, Biological and Chemical Sciences | Year: 2014
The results showed that the application of therapeutic and prophylactic immunoglobulin marked elevation in the specific and specific resistance of the body of pigs and cattle, as well as the use of their young. The drug ≪Therapeutic and prophylactic immunoglobulins≫ can be used for: the prevention of immune deficiency, increasing natural resistance in diseases accompanied by a decrease in specific and nonspecific resistance, reduce morbidity and improve the safety of young pigs and cows.
Yurievich S.S.,Mari State University |
Konstantinovna P.E.,Kazan Bauman State Academy of Veterinary Medicine |
Harisovich V.A.,Kazan Bauman State Academy of Veterinary Medicine |
Rasihovna Y.G.,Kazan Bauman State Academy of Veterinary Medicine |
And 3 more authors.
Research Journal of Pharmaceutical, Biological and Chemical Sciences | Year: 2016
At the present stage of development of dairy cattle breeding the main objective of biological science consists in finding rational ways of an exction or neutralization of action of adverse technogenic and ecological factors. The oganism is especially sensitive to influences of adverse factors of environment. The veterinary pharmaceutical market offers the big range of the preparations capable to stimulate protective forces of an organism and to increase resilience to adverse factors. One of such preparations is «Treatment-and-prophylactic immunoglobulin» the let-out Federal State Budgetary Institution Federal Center Toxicological, Radiation and Biological Safety (Russia, Kazan). The purpose of these researches was studying of influence of an immunostimulator "Treatment-and-prophylactic immunoglobulin" on a veterinary and sanitary assessment of meat and a histologic picture of parenchymatous bodies of cattle. Researches were conducted on a farm on sagination of cattle in SHA "Spark" of Kuzhenersky district of the Republic of Mari El where two groups of bull-calves of black and motley breed with a live weight of 420 kg of 5 animals in each group have been created. An animal of the first groups have intramuscularly injected the drug "Treatment-and-prophylactic Immunoglobulin" in a dose of 20 ml with an interval of 48 hours twice. Animals of the second of groups served as control and contained on a usual diet. In 30 days after the beginning of experiment carried out a face of animals up to 3 heads from each group. For a veterinary and sanitary assessment took 2 samples of meat from muscles of sgibatel and razgibatel of chest and pelvic extremities of hulk 10 centimeters long. In meat defined ΡH, the content of aminoammoniac nitrogen, zinc, copper, iron, cobalt, selenium, magnesium, lead, cadmium, mercury, arsenic. Carried out reaction to peroxidase and with sulfate copper for definition of freshness of meat. For histologic researches took 3 samples of 2×4 cm in size from a liver, kidneys, a myocardium, lymph nodes and a spleen. Pathological material was placed in a vessel with 10% water solution of formalin. Then pieces of fabric filled in with paraffin with a temperature of 55 °C and left for 2 hours. After that by means of the microtome made histologic cuts 5-7 microns thick and painted hematoxylin-eozinom. Researches of structure of fabrics and cages of bodies carried out by means of a microscope of "Leica DM 1000". Photography was carried out on the Nikon coolpix 4500 digital camera. Researches have shown that ΡH meat of skilled group I made 5,32±0,03, and in control - 5,43±0,02, the level of aminoammoniac nitrogen - 1,19±0,02 and 1,21±0,01 mg respectively in skilled and control groups. Reaction to peroxidase both in skilled, and in control groups was positive, and reaction with sulfate copper - negative. content of copper was above control for 34% (1,80±0,03 mg/kg). Concentration of zinc has made 38,5±1,32 and 23,1±0,98 mg/kg respectively in skilled and control groups. Iron levels, both in skilled, and in control groups were similar among themselves. Content of cobalt in meat of bull-calves was above an indicator of control group for 24,6%. Concentration of selenium and magnesium in meat of bull-calves of skilled group was higher in comparison with control. Such heavy metals as lead, cadmium, mercury, and arsenic in meat of skilled and control groups haven't been found. By results of histologic researches it is established that this preparation doesn't cause pathological changes in a structure of a liver, kidneys, a myocardium, lymph nodes and a spleen. © 2010 RJPBCS.