Basaveshwara Medical College and Hospital
Basaveshwara Medical College and Hospital
Rao S.V.M.,Basaveshwara Medical College and Hospital
Clinical Rhinology | Year: 2017
Aim: To evaluate the efficacy and results of radiofrequency turbinoplasty in patients with rhinitis medicamentosa due to imidazolines like oxymetazoline and xylometazoline. Study design: This is a prospective, single-blinded, randomized controlled study. Materials and methods: Study was conducted on 20 patients in a tertiary level center from January 2010 to February 2016. Patients with symptoms and signs of nasal obstruction due to rhinitis medicamentosa were selected. Patients were aged from 16 to 43 years (mean age is 24 years). Twelve were males and eight were females. The duration of use of nasal decongestant drops varied from 3 months to 5 years. The turbinoplasty was performed using the radiofrequency method. Nasal obstruction symptom evaluation (NOSE) questionnaires are used for subjective assessment and nasal endoscopy view score (NES) was used for objective assessment pre- and postoperatively. Follow-up was done at the end of 15 days and 3 months after surgery. The results were statistically analyzed by paired t-test. Results: The mean NOSE score before procedure was 92. At the 15th postoperative day, mean NOSE score reduced to 1.3 and it further reduced at the 3rd month to 0.5 (p < 0.001), with 99.5% reduction in subjective symptoms. The mean NES before procedure was 3.95. On the 15th day, it was 0.35 and at the end of 3rd month, it was 0 with 91.1% reduction in objective evaluation (p < 0.001). Results were same on left and right side of nose. No major postoperative complication was observed in patients. Conclusion: Radiofrequency turbinoplasty technique can be recommended as an effective method in imidazoline-induced rhinitis medicamentosa. It is simple, comfortable, fast relief giving, no repeated steroids, and cost-effective, single-session treatment. Good compliance and cooperation from patients can be obtained with no major complications of the treatment. It allows patients to be managed in the office environment. © 2017, Jaypee Brothers Medical Publishers (P) Ltd. All rights reserved.
Ramanath B.,Basaveshwara Medical College and Hospital |
Amar Kumar G.,Salem College
International Journal of Pharmacognosy and Phytochemical Research | Year: 2012
Objective: A Phytochemical and antimicrobial activity of leaf extracts of Momordica cymbalaria Hook Fenzl. Method: Distilled water and methanolic crude extracts of leaves of the plant were evaluated for antimicrobial activity using the disk diffusion method and also done MIC, MBC and MIC index on eight reference microorganisms Escherichia coli,Staphylococcus aureus, Shigellasps, Klebsiellasps, Salmonella, Pseudomonas, Proteus vulgarisand Candida were used as test organisms. Result:Momordica extracts may be useful as a broad-spectrum antimicrobial agent. Methanolic and Distilled water extract of Momordica exhibited potent activity against all set of micro organisms used. It showed better action against Staphylococcus and least action on Pseudomonas. Conclusion:Leaf extracts of M.cymbalaria demonstrated antimicrobial activity on tested microorganisms. It is having bactericidal property on all used micro organisms.
Rao S.V.M.,Basaveshwara Medical College and Hospital |
Rajshekar M.M.,Basaveshwara Medical College and Hospital
Clinical Rhinology | Year: 2016
Aim: To study surgical outcome in dacryocystorhinostomy (DCR) stent insertion in initial endoscopic DCR and the complications associated with the surgery. Study design: This is a prospective, single-blinded, randomized, controlled trial. Materials and methods: The study was carried in a tertiary level center (period between November 2009 and February 2015). A total of 50 patients with epiphora due to nasolacrimal duct obstruction were divided randomly into two groups-with one group undergoing endoscopic DCR with stent and the other group undergoing endoscopic DCR without stent. The postoperative results were assessed subjectively and objectively after 3 and 6 months and also for complications of the procedure. The results were statistically analyzed by chi-square test. Results: There was significant postoperative improvement across all participants and within both groups. A total of 92% of patients in the stent group and 84% of patients in the without stent group improved. There was no significant difference with respect to complications. Synechiae and secondary hemorrhage were the most common complications in the without stent group and stent group respectively. Conclusion: The present study shows that statistically significant difference in results is not achieved by inserting stents initially. But, whenever there is excessive bleeding during surgery, which masks endoscopic picture, or when bony stoma created is small because of thick bone and poor access, when atrophic sac is present, or when adhesions are expected due to pus in sac, then stenting should be done without hesitancy. Best time to do stenting is when surgeons’ first think of stenting. Regular postoperative follow-up is necessary as any defect like synechia and granulation tissue formation can be dealt with immediately. © 2016, Jaypee Brothers Medical Publishers (P) Ltd. All rights reserved.
Kumar S.,Basaveshwara Medical College and Hospital |
Raju M.,JJM Medical College |
Gowda N.,Basaveshwara Medical College and Hospital
Indian Journal of Pediatrics | Year: 2010
Objective. To find out the association between parental obesity and Childhood obesity. Methods. Children in middle schools were screened for obesity. For each obese child two controls were studied. Results. Parental history of obesity was present for 32.7% of obese children. Children with parental history of obesity showed 25.2 times more chances of developing obesity than controls. 33.8% of the obese girls and 31.6% of the obese boys had history of parental obesity. If the father was obese, boys had 6.5 times more chance and girls had 40.1 times more chance of developing obesity. Mother's obesity had an influence on 23.7 % of the boys and only 16 % of the girls. Conclusion. The childhood obesity has been influenced by genetic factors in the present study and it also shows that maternal obesity mainly passes to boys and paternal obesity to girls.
Ramanath Royal B.,Basaveshwara Medical College and Hospital
International Journal of Pharma and Bio Sciences | Year: 2012
Tapentadol is a centrally acting FDA approved analgesic for the treatment of moderate to severe acute pain with a dual mode of action as an agonist at the μ-opioid receptor and as a nor epinephrine reuptake inhibitor. It is used in chronic pain like, post operative, Neuropathic pain and End- stage degenerative joint disease. Oral dosages of 50 mg, 75 mg, or 100 mg /six hours tablets are available. Common side effects nausea, vomiting, dizziness, somnolence, headache, decreased seizure thresh hold, fatigue and also has dependence liability.
Ammanagi A.S.,Sn Medical College |
Chikkannaiah P.,Jn Medical College |
Yenni V.,Basaveshwara Medical College and Hospital |
Dombale V.D.,Sn Medical College
Indian Journal of Dermatology | Year: 2013
We report a case of cutaneous swelling found on the left anterior axillary fold of a 41-year-old man. Gross examination of specimen excised from the dermis showed a well-circumscribed nodule histologically composed of spindle cells with interspersed ganglion cell like cells. On hematoxylin and eosine (H and E) staining it was diagnosed as ganglioneuroma. Ganglioneuromas are rare, benign, fully differentiated tumors that contain mature schwann cells, ganglion cells, fibrous tissue, and nerve fibers. They are commonly found along the paravertebral sympathetic ganglia and sometimes in the adrenal medulla. However primary cutaneous ganglioneuroma is an extremely rare tumor. Immunohistochemical workup revealed a fibroblastic origin and hence the case was diagnosed as fibromatosis with ganglion cell like fibroblasts. This case report suggests that the features considered diagnostic of ganglioneuromas can occur in other cutaneous lesions and, therefore, this diagnosis cannot be offered only on the basis of H and E.
Rajeev K.H.,Basaveshwara Medical College and Hospital
Indian journal of public health | Year: 2012
HIV/AIDS is fatal illness which leaves the victim vulnerable. Quality of life in individuals living with HIV/AIDS is becoming crucial for measuring commonly used endpoints. The study of psychosocial factors also influences the health outcome of People Living with HIV/AIDS. To assess the Quality of life of PLHA in relation to various socio-demographic and clinical correlates. A community care center in Chitradurga district and it is a Cross sectional study. About 395 PLHAs registered in the centre constituted the sample. WHOQOL - 120 instrument was used for assessing quality of life. The socio demographic factors were also obtained in pre designed proforma. Proportions, Mean, Std deviation, One way Analysis of Variance (ANOVA). The Quality of Life scores for all domains were intermediate for the PLHAs between (10 - 14). The mean scores were highest for psychological domain. There was a significant difference in QOL of PLHA who were on ART and Not on ART in some domains. PLHAs who were literates, married, Single, employed, income more than 1500 not on ART, CD4 count more than 200, earlier stages of HIV, living with spouse and students had high mean scores. Mean difference of QOL scores with duration of ART intake were statistically significant in psychological and Spirituality domains. QOL was found to be determined by education, income, occupation, ART status, duration of taking ART and clinical categories of the disease.
Yuvaraj B.Y.,Ss Institute Of Medical Science |
Nagendra Gowda M.R.,Basaveshwara Medical College and Hospital |
Umakantha A.G.,J J M Medical College
Indian Journal of Community Medicine | Year: 2010
Objective: To study the prevalence, awareness, treatment, and control of hypertension in the rural areas of Davanagere. Type of Study: Cross-sectional community-based study. Setting: Villages belonging to six sectors of the Davanagere Taluk. Materials and Methods: General population above 18 years. Methodology: A community-based sample was chosen by a multistage sampling technique. Subjects were screened for hypertension by a house-to-house survey. Subjects with systolic blood pressure more than 140 and diastolic blood pressure more than 90 mm of Hg, on hypertensive treatment, and history of hypertension were classified as hypertensives. The data thus obtained was compiled and analyzed. Results: The prevalence rate of hypertension in the study population was 18.3% (95% CI, 16.7-19.9%). Prevalence of hypertension was more in males 19.1% (95% CI, 16.7-21.5%) than in females 17.5% (95% CI, 14.9-20.1%); 11.6%, 5.6%, and 1.2% of the total subjects had Grade I, Grade II, and Grade III, respectively. Only 33.8% of them were aware of their hypertensive status. Hypertensives of 32.1% were on treatment, and 12.5% adequately controlled their BP. About 6.9% of the total hypertensives had severe hypertension. Statistical Analysis: Proportions, One way Analysis of Variance, Chi-square test.
PubMed | Vijayanagara Institute of Medical science, Sri Devaraj Urs Medical College and Basaveshwara Medical College and Hospital
Type: Journal Article | Journal: Journal of translational internal medicine | Year: 2016
Tuberculosis (TB) and the human immunodeficiency virus (HIV) infection have reached epidemic proportions in our country. This study was undertaken to know the seroprevalence of HIV infection among TB patients and to evaluate the various clinical features of TB in seropositive and seronegative patients. This study was undertaken in Vijayanagara Institute of Medical Sciences, Bellary. It was cross-sectional comparative observational study conducted from December 2010 to May 2012.A total of 100 consecutive patients diagnosed with TB satisfying inclusion criteria were selected for the study. All patients went through a detailed evaluation along with testing for HIV seroprevalence. Chi-square and Students The overall HIV seroprevalence among TB patients was 8%. Seroprevalence was highest in the age group between 31 and 40 years at 29.41% (odds ratio [OR] = 11.11, Human immunodeficiency virus seroprevalence is quite high among TB patients in Bellary. During the evaluation of TB patients, the possibility of HIV co-infection should be kept in mind, and thus adequate knowledge of the likely clinical features is absolutely necessary.
PubMed | Vijayanagara Institute of Medical science, Professor and Basaveshwara Medical College and Hospital
Type: Journal Article | Journal: Journal of clinical and diagnostic research : JCDR | Year: 2016
Plasma sialic acid levels are elevated in Diabetes Mellitus (DM) patients with proteinuria. Renal damage is mainly caused by free radicals that are excessively generated in DM. Thiols play an important role in the cellular antioxidative defence mechanisms mainly through thiol-disulphide exchange reaction. Diallyl disulphide, a garlic oil principle component, is known for its anti-diabetic properties. Its structural analogue, Diaceto-Dipropyl Disulphide (DADPDS), is a less toxic and more palatable disulphide and possesses similar anti-diabetic actions.This study was undertaken to assess the usefulness of DADPDS in prevention of de-sialation of Glomerular Basement Membrane (GBM) in alloxan diabetic rats and to assess effect of DADPDS on renal tissue thiol levels.Rats were divided into Normal, Diabetic and DADPDS treated diabetic groups. Diabetes was induced by intraperitoneal injection (IP) of alloxan. DADPDS was fed by gastric intubation. Plasma Sialic acid was determined by Ehrlichs method and renal tissue thiol levels by Nitroprusside reaction method.This study showed a significant decrease (p<0.001) in plasma sialic acid, plasma glucose and renal tissue TBARS levels along with significant increase (p<0.001) in renal tissue thiol levels in DADPDS treated alloxan diabetic rats when compared to diabetic control rats.Hence it may be concluded that DADPDS helps in preventing de-sialation of GBM in alloxan diabetic rats and improves renal tissue antioxidant defence mechanisms, may be through thiol-disulphide exchange reaction and thereby exhibits a possible clinical use in prevention of renal complications like diabetic nephropathy.