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Chitradurga, India

Usha M.G.,JJM Medical College | Shwetha D.C.,Basaveshwara Medical College | Vishwanath G.,JJM Medical College
Indian Journal of Pathology and Microbiology | Year: 2013

Background: Despite their frequency as contaminants, coagulase-negative Staphylococci (CONS) have become important nosocomial pathogens, accounting for 9% of all nosocomial infections. These infections are difficult to treat because of the risk factors and the multiple drug resistance nature of these organisms. Materials and Methods: One hundred and two consecutive CONS were isolated from various clinical samples like blood, pus, urine, urine catheter tip and gastric lavage. Most of the blood samples were from patients with risk factors (immunocompromised or on medical devices). After confirming the isolates as CONS, species-level identification was performed by simple, non-expensive conventional methods and antibiotic sensitivity testing was also carried out. Results: Of 102 CONS isolates, 100 isolates could be identified to the species level. Among the 100 isolates, epidermidis was the most common species isolated, seen in 32%, followed by S. hemolyticus (18%), S. lugdunensis (12%), S. hominis (10%), S. saprophyticus (8%), S. capitis (6%), S. caprae (4%), S. xylosus (4%), S. cohni and S. warneri (3% each). In the present study, 56% of the isolates were methicillin-resistant CONS. Most of the isolates showed resistance to ampicillin and amoxyclav (89% each), followed by ceftriaxone (52%), cotrimoxazole (46%), cefotaxime (32%), gentamicin (25%), amikacin (21%). Conclusion: The increased pathogenic potential and multiple-drug resistance demonstrates the need to adopt simple, reliable and non-expensive methods for identifying and determining the antibiotic sensitivity of CONS.

Shruthi N.,Anand Diagnostics Laboratory | Ravikumar,Korea Institute of Materials Science | Ravishkumar,Basaveshwara Medical College
Journal of Clinical and Diagnostic Research | Year: 2012

Introduction and Objective: The bacterial strains that cause symptomatic urinary tract infections possess diverse distinctive properties that enable them to overcome the local host defenses. In Escherichia coli, virulence results from the cumulative impact of several virulence factors, which can vary according to the patient populations. Hence, a study was undertaken to assess the prevalence of the virulence factors in the E.coli isolates which were isolated from pregnant woman, catheterized patients and from the stool samples of healthy individuals. Methods: A total of 93 E.coli isolates were obtained from symptomatic cases of urinary tract infections and 31 E.coli faecal isolates were obtained from apparently healthy individuals and they were tested for haemolysin production, mannose resistant haemagglutination to indicate P fimbriae, cell surface hydrophobicity, and the gelatinase enzyme. Results: Among the 93 E.coli isolates from the cases group, 39(41.9%) were haemolytic, 38(40.9%) were MRHA positive, 29(31.2%) were hydrophobic and 18(19.4%) were positive for gelatinase. Among the 31 controls, 01(3.2%) were haemolytic, 02(6.5%) were MRHA positive and 03(9.7%) were hydrophobic and none of the isolates were positive for gelatinase. The difference between the cases and the control group was significant (P<0.001).Multiple virulence factors were observed in 10% of the isolates. Interpretation and Conclusions: The present study showed that the expression of the virulence factors was more in the urinary isolates of the antenatal cases and in the catheterized patients as compared to the faecal isolates.

Vani D.,T K Layout | Dayananda T.R.,Sarvad Skin Center and Diagnostics Advanced | Kumar H.R.S.,Basaveshwara Medical College | Ravikumar V.,MVJ Medical College and Hospital
Journal of Clinical and Diagnostic Research | Year: 2013

Hidrocystomas are rare cystic lesions that form benign tumours of the sweat glands. In this report, a clinical case of multiple apocrine hidrocystomas on both the upper and lower eyelids, and on both the malar regions has been discussed. These lesions are less likely than the eccrine lesions to occur at the periorbital region.

Patil S.,Basaveshwara Medical College | Nidoni M.,Sjm Dental College And Hospital | Mahesh G.M.,Basaveshwara Medical College
Irish Journal of Medical Science | Year: 2014

Daniel John Cunningham was born on 15 April 1850 in Scotland. After his initial schooling at his home town, Crieff, he took up the study of medicine at the University of Edinburgh and passed with honours. He is best known for the excellent series of dissection manuals, namely Cunningham's Dissection Manuals. Apart from this, he also produced many scientific contributions not only in the field of descriptive anatomy but also in comparative anatomy, evolution, anthropology and anthropometry. He was also a very able administrator, not only of medical schools but also in other Governmental departments, scientific journals, zoological gardens and other societies. He was also passionate about animals and gardens. He was a much respected man at both the cities of Edinburgh and Dublin. Above all, he strove for excellence with a human touch and his colleagues remembered him as a great human being. He passed away on 23 June 1909 at his home in Edinburgh. © 2014 Royal Academy of Medicine in Ireland.

Kumar H.R.S.,Basaveshwara Medical College | Dsouza H.L.,Manipal University India | Belodu R.,Basaveshwara Medical College
Journal of South India Medicolegal Association | Year: 2011

Forensic work related to exhumations can be one of the most daunting as well as challenging exercise as various factors interplay to confound and confuse. Most of them are related to the effects of decomposition which causes destruction of tissues resulting in loss of valuable evidence and introduces postmortem artefacts. With regard to one of the primary autopsy objectives of personal identification the advent of DNA typing has proved to be a major tool, especially in cases where routine methods of identification are inadequate. Herein we report a case where DNA typing played a pivotal role in personal identification of the exhumed human remains with eventual administration of social justice. © 2011 South India Medico-Legal Society. All rights reserved.

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