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Shanghai, China

Sun J.-Z.,Baoshan Central Hospital | Tai M.,Baoshan Central Hospital | Ren D.,Baoshan Central Hospital | Shi G.-T.,Baoshan Central Hospital | And 2 more authors.
Journal of Clinical Rehabilitative Tissue Engineering Research | Year: 2010

BACKGROUND: Vertebroplasty is used widely in spinal surgery, and its effect is favorable. There are few reports on the influential factors, and only a small amount of individual factors are discussed. OBJECTIVE: To analyze 22 possible factors to find factors that affect vertebroplasty treatment of thoracolumbar compression fracture, and to establish the multiple linear regression equation. METHODS: A total of 61 patients with vertebral compression fractures were followed up for an average time of 17 months. The visual analog scale (VAS) scores of patients were determined before and after treatment, and the average value of each patient was obtained. The patients were interviewed to assess treatment results. Relationship between influential factors and VAS was analyzed using SAS9.1.3 software. RESULTS and CONCLUSION: The treatment effect of vertebroplasty was positive. The outcome of the vertebroplasty surgery was correlated with the course of the disease, the characteristics of the used surgery instruments and internal fixation treatment. Sky instruments were better than Kyphon ones. Moreover, appropriate internal fixation using pedicle screw system, operation indications, and early diagnosis and treatment of vertebral compression fractures are highlighted in vertebroplasty.

Zhao J.,Baoshan Central Hospital | Hu J.,Baoshan Central Hospital | Lu H.,Baoshan Central Hospital | Yang L.,Baoshan Central Hospital
Experimental and Therapeutic Medicine | Year: 2014

The aim of the present study was to investigate the pathomorphological and functional variations of choroidal neovascularization (CNV) in age-related macular degeneration (AMD) in a Chinese population using optical coherence tomography (OCT). This population-based study enrolled 59 patients (age, >45 years; eyes, 70) with early and intermediate-stage AMD from Youyi Road Community, Baoshan District, Shanghai, China. Comprehensive standardized ophthalmic examinations included visual acuity, anterior segment analysis using a slit lamp, dilated fundus evaluation by direct ophthalmoscopy, 90D handheld lens analysis, fundus photography, fundus fluorescein angiography (FFA) and fast optic disk scans using OCT. The macular CNV characteristic profiles in early and intermediate-stage AMD were determined by OCT. Data were obtained on the first visit and the follow-up period ranged between 6 and 24 months, where FFA and OCT outcomes of early and intermediate-stage AMD patients were analyzed. Three profiles of early and intermediate-stage AMD were created from the OCT and FFA results, each with a different prognosis. Firstly, drusens with unclear boundaries and evident pigment proliferation, as well as hypofluorescence around the drusens, was observed via FFA. A slight small arch field located in the retinal pigment epithelium (RPE)/choriocapillary layer (CCL) was shown on OCT scans, indicating exudative AMD. Secondly, RPE detachments of >1 pupillary distance, without CNV in the macular area, indicated geographic chorioretinitis atrophy. Finally, drusens with clear boundaries and few pigment proliferations and no certain surrounding fluorescence was observed via FFA, while a clear RPE/CCL band on the OCT scans indicated slow progress. The results of the present study demonstrated that combined OCT and FFA was the most efficient method for identifying CNV and diagnosing AMD. If the two techniques are not available concurrently, then OCT is a safer and more reliable technique to follow-up early and intermediate-stage AMD patients.

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