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Han J.-F.,Xian Jiaotong University | Wang C.-T.,Hospital of Chinese Traditional Medicine of Baoji | Yang J.-B.,Xian Jiaotong University | Guo F.,Xian Jiaotong University | Li Z.-Y.,Xian Jiaotong University
Academic Journal of Xi'an Jiaotong University

Objective: To study the clinical features and angiographic findings of moyamoya disease (MMD) as well as their relationship. Methods: A total of 22 MMD patients received routine digital substraction angiography (DSA). The clinical manifestations and angiographic findings were analyzed. Results: Clinical manifestations varied and each patient often had multiple symptoms, including cerebral infarction in 9 patients with an average age of 23.6 (13-39 years) and cerebral hemorrhage in 7 patients with an average age of 31.2 (28-46 years). Angiographic examination found that all the diseased sides showed MMD blood vessels. The patients who received encephalo-myo-arterio-synangiosis (EMAS) had better prognosis than those without receiving the treatment. Conclusion: Cerebral infarction is frequent in children and adolescents with MMD, whereas cerebral hemorrhage is common in adults. DSA is a golden criterion for diagnosing MMD. Surgical treatment, EMAS blood supply reconstruction in particular, should be prescribed. Source

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