Ahuja H.,NorthCap University |
Sujata,NorthCap University |
Purohit G.N.,Banasthali Vidyapeeth
Proceeding - IEEE International Conference on Computing, Communication and Automation, ICCCA 2016 | Year: 2016
Software is becoming progressively more integral part of day-to-day life. Developing the software that meet stakeholders' need is the ultimate goal in today's environment. As the complexity of software increases so does the requirements. There are many requirements which should be fulfilled in the given time duration on the other hand some requirements should be considered first to reduce the risks. Hence, proper gathering and prioritizing requirements may leads to the successive development of the software. In literature there are number of techniques which focus on requirement prioritization problem. This paper presents the comparative study of various requirement prioritization techniques. © 2016 IEEE.
Kaur N.,BVICAM |
Taruna S.,Banasthali Vidyapeeth
2015 International Conference on Computing for Sustainable Global Development, INDIACom 2015 | Year: 2015
The MapReduce programming model accepted by Hadoop and other big datatechnologies is a powerful toolto address big data analysis problem. It is becoming ubiquitous, but still there are issues in concern with its performance and efficiency. It offers high scalability and fault tolerance in large scale data processing, but gives low efficiency. Hence, how to enhance efficiency with high level of scalability and fault tolerance is a major challenge. The efficiency problem, especially I/O costs can be addressed in two ways: by optimizing I/O operations in Map-Reduce and by utilizing the features of modern hardware such as SSD (Solid State Disk) that can help in minimizing computations in Map-Reduce considerably. This paper explores various existing data layout structures that can improve the efficiency of map-reduce operations and help in overcoming its pitfalls. © 2015 IEEE.
PubMed | Banasthali Vidyapeeth and Indian Agricultural Research Institute
Type: Journal Article | Journal: Indian journal of microbiology | Year: 2016
Majority of animals form symbiotic relationships with bacteria. Based on the number of bacterial species associating with an animal, these symbiotic associations can be mono-specific, relatively simple (2-25 bacterial species/animal) or highly complex (>10(2)-10(3) bacterial species/animal). Photorhabdus (family-Enterobacteriaceae) forms a mono-specific symbiotic relationship with the entomopathogenic nematode Heterorhabditis. This system provides a tractable genetic model for animal-microbe symbiosis studies. Here, we investigated the bacterial factors that may be responsible for governing host specificity between nematode and their symbiont bacteria using proteomics approach. Total protein profiles of P. luminescens ssp. laumondii (host nematode- H. bacteriophora) and P. luminescens ssp. akhurstii (host nematode- H. indica) were compared using 2-D gel electrophoresis, followed by identification of differentially expressed proteins by MALDI-TOF MS. Thirty-nine unique protein spots were identified - 24 from P. luminescens ssp. laumondii and 15 from P. luminescens ssp. akhurstii. These included proteins that might be involved in determining host specificity directly (for e.g. pilin FimA, outer membrane protein A), indirectly through effect on bacterial secondary metabolism (for e.g. malate dehydrogenase Mdh, Pyruvate formate-lyase PflA, flavo protein WrbA), or in a yet unknown manner (for e.g. hypothetical proteins, transcription regulators). Further functional validation is needed to establish the role of these bacterial proteins in nematode-host specificity.
Gudlawar S.K.,Waters India Pvt Ltd |
Dwivedi J.,Banasthali Vidyapeeth
Journal of Liquid Chromatography and Related Technologies | Year: 2014
A new, sensitive, and rapid UPLC-MS method for the determination of 1-chloro-2-nitrobenzene in ultra performance liquid chromatography mass spectrometry using substitution reactions in atmospheric pressure chemical ionization negative mode [APCI (-)] is described. Substitution reactions [M - X + O]- are observed for compounds which do not easily undergo deprotonation. By using threshold of toxicological concern (TTC), a limit of 1.63 ppm was calculated based on maximum daily dose of the drug substance. The proposed method was found to be linear from 50.0 to 2000.0 ppb with correlation coefficient >0.99. LOD and LOQ of the method were very low as 20.0 and 50.0 ppb. The accuracy of the method was found to be in the range of 85-105%. This method is a good quality control tool for quantification of 1-chloro-2- nitrobenzene at low levels in quetiapine fumarate. © 2014 Taylor & Francis Group, LLC.
Choudhary K.,ITM University |
Purohit G.N.,Banasthali Vidyapeeth
2014 Recent Advances in Engineering and Computational Sciences, RAECS 2014 | Year: 2014
Software Testing is the critical task for any software which helps in building trust and confidence in the product. Usually, the emphasis is on Manual Testing but to reduce cost there is a need of automation in software testing process. This paper proposes a method to generate automated uniformly distributed test cases based on the platform of multi-objective genetic algorithm (MOGA). The proposed method is analyzed on the domain of Pareto-Optimality, Dominance and Multi-objective Genetic Algorithm. © 2014 IEEE.
Agarwal M.,BHU |
Sharma A.,Banasthali Vidyapeeth
Journal of Health Management | Year: 2011
The study was conducted with the aim of investigating the effects of perception of the hospital workplace factors on the job satisfaction and psychological well-being of a sample of paramedical health care employees (N = 200) from a medical college (teaching) hospital and public (non-teaching) government-run hospitals. Statistical analysis of the data revealed that despite significant differences in perceived work-place factors, the reported levels of psychological well-being and job satisfaction of the participants were nearly similar in the two types of public hospitals. Stepwise regression analysis of the data revealed that the organization's structure-related factors, co-ordination and work autonomy were significantly predictive of job satisfaction and psychological well-being of health care employees, while the process-related workplace factors, participative decision making and intra-professional relations, emerged as significant predictors of psychological well-being and job satisfaction in both types of hospitals. Results have significant implications for public hospitals which are currently facing competition from the state-of-the-art health care technology being introduced by private hospitals, and are therefore under pressure for retention of skilled health care employees. © 2011 SAGE Publications.
Singh G.,Malaviya National Institute of Technology, Jaipur |
Sirohi A.K.,Banasthali Vidyapeeth |
Verma S.,Banasthali Vidyapeeth
Physics of Wave Phenomena | Year: 2013
A 3-dB optical coupler (power splitter) based on a Y-junction waveguide with a channel profile of proton-exchanged lithium niobate has been modeled. Finite difference beam propagation method has been used to investigate light wave propagation in axially varying waveguides. It is found that the structure splits the input power equally at the Y-junction with an efficiency of 99% and an average excess loss ≤0.04 dB. The novelty of the coupling structure proposed is its capability to function as a wavelength-independent 3-dB coupler while maintaining very low-power imbalance for widespread optical communication wavelengths of 1.3 and 1.55 μm. © 2013 Allerton Press, Inc.
Kumari S.,Banasthali Vidyapeeth
2013 4th International Conference on Computing, Communications and Networking Technologies, ICCCNT 2013 | Year: 2013
High Performance Distributed Computing has created a new approach to science. High performance can be achieved by distributing the task over different machines, using a better algorithm, using faster computers or by using an MPSoC (Multiple Processor System on Chip). In MPSoC multiple CPUs are connected with each other to accomplish a task as a whole. Each CPU assigned a different task. In this paper we have compared the computation speed of a Linux based cluster and an MPSoC by running the same application and repeated this for different applications, which gives the high performance for the distributed systems. For this we have created a cluster of five Linux based systems by using a complete clustering solution that is OSCAR-5.1b2 which is fully supported for RHEL-5(Red Hat Enterprise Linux-5) and an MPSoC with the help of Embedded System Environment Tool which produce Transaction level model for functional verification and performance estimation. © 2013 IEEE.
PubMed | Banasthali VidyaPeeth, CSIR - Central Electrochemical Research Institute and a Pharmaceutics Division and.
Type: Journal Article | Journal: Drug delivery | Year: 2016
The purpose of this study was to prepare and characterize the complexes between curcumin (CU) phosphatidylcholine (PC) and hydrogenated soya phosphatidylcholine (HSPC) and to evaluate their anticancer activity. These CU-PC and CU-HSPC complexes (CU-PC-C and CU-HSPC-C) were evaluated for various physical parameters like Fourier transform infrared spectroscopy, melting point, solubility, scanning electron microscopy and the in vitro drug release study. These data confirmed the formation of phospholipids complexes. The in vitro hemolysis study showed that the complex was non-hemolytic. The anti-cancer potential of the complexes was demonstrated by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide assay in MCF-7 cell line. This increase may be due to the amphiphilic nature of the complexes, which significantly enhances the water and lipid solubility of the CU. Unlike the free CU (which showed a total of only 90% drug release at the end of 8h), complex showed around 40-60% release at the end of 8h in dissolution studies. It showed that (when given in equimolar doses) complexes have significantly decreased the amount of CU available for absorption as compared with CU-free drug. Both CU-PC-C and CU-HSPC-C were found to be non-toxic at the dose equivalent to 2000mg/kg of body weight of CU in the toxicity study. Acute and subacute toxicity studies confirmed the oral safety of the formulation. A series of genotoxicity studies was conducted, which revealed the non-genotoxicity potential of the developed complexes. Thus, it can be concluded that the phospholipid complexes of CU may be a promising candidate in cancer therapy.
PubMed | Banasthali Vidyapeeth and CSIR - Central Electrochemical Research Institute
Type: Journal Article | Journal: Drug delivery | Year: 2016
Withania somnifera Dunal (Solanaceae) known as Ashwagandha, a popular plant of Indian origin is known to possess tremedous medicinal potential, often used as anti-inflammatory, anti-platelet, antihypertensive, hypoglycemic, hypolipidemic and adaptogenic candidate. Some of its chemotypes developed by CSIR, India includes NMITLI-101, NMITLI-118, NMITLI-128. In this study the investigators have attempted development of a phytosomal complex of NMITLI118RT+(standardized ethanolic extract of a new chemotype of W. somnifera Dunal.), its pharmaceutical characterization and evaluation of its neuro-protective potential against experimenal stroke in rats in continuation with their previous work in this area. The phytosomal complex (NIMPLC) was prepared by following a cohesive optimization design and was characterized on the basis of solubility, dissolution profile, FT-IR, DSC-TGA analysis, zeta potential, physical stability, forced degradation and photolytic degradation. Results were suggestive of a pharmaceutically acceptable formulation. NIMPLC was taken up further for biological evaluation using the middle cerebral artery occlusion (MCAO) model in rats. It could be demonstrated that the beneficial effects of NMITLI118RT+could be augmented by NIMPLC in 1h pre and 6h post treatment as was evident from reduction in MDA levels, increment in GSH levels, reduction in neurological deficit (ND) scores and reduction in infarct size. The study could successfully demonstrate the beneficial effects of NIMPLC in brain function restoration following stroke.