PubMed | Rafsanjan University of Medical Sciences, Shahid Bahonar University of Kerman, Kerman Medical University and Bam University of Medical science
Type: | Journal: Journal of religion and health | Year: 2016
Blindness is one of the most complex problems related to health throughout the world. The condition is worse when such stress is accompanied with cancer. The aim of this case study was to introduce a patient with both these conditions who could come over her problems well. A phenomenological hermeneutic approach influenced by Ricoeur was used to explore the experience of the patient. Data were collected through unstructured and deep interview and by checking patient medical records. The patient is an Iranian 58-year-old teacher residing in Kerman who became blind at age 32 due to bloodshed inside the eye and was affected by breast cancer at age 52. The patient could come over these divine tests through the help of spirituality so that she believed blindness and cancer was the best events in her life. Spirituality is one of the human aspects that give meaning and purposes to life. Health care providers are suggested to implement spiritual strategies such as instructional workshops for increasing spirituality in settings, such as oncologic wards for patients to pass stages of adaptation to such great stresses easily and rapidly.
Khajehpour M.,Bam University of Medical Science |
Simbar M.,Shahid Beheshti University of Medical Sciences |
Jannesari S.,Shahid Beheshti University of Medical Sciences |
Ramezani-Tehrani F.,Shahid Beheshti University of Medical Sciences |
Majd H.A.,Shahid Beheshti University of Medical Sciences
Public Health | Year: 2013
Objectives: Unintended pregnancy may have negative impacts on maternal health. However, no comprehensive studies have been undertaken on the health of women with intended and unintended pregnancies. This study aimed to compare the health status of women with intended and unintended pregnancies in Iran. Study design: Comparative study. Methods: Two hundred women were included in this study: of these, 100 had intended pregnancies and 100 had unintended pregnancies. The participants were recruited using a multi-stage sampling method from the health centres of Kerman, Iran in 2010. The tools for data collection included: a questionnaire to assess demographic characteristics and fertility history; the Short Form-36 (SF-36) questionnaire to assess general physical and mental health status; and a questionnaire to assess pregnancy-related health status. Validity and reliability of the questionnaires were assessed before use. Results: In comparison with women with intended pregnancies, women with unintended pregnancies had lower scores for physical and mental health status; less prenatal care; lower scores for self-care behaviours such as use of supplements, vaccination and nutrition; lower scores for personal health; and higher rates of risky behaviours such as smoking, drinking alcohol and drug abuse during pregnancy (P < 0.05). Conclusion: Unintended pregnancy is a threat to the physical and mental health of women. As unintended pregnancy is associated with lower self-care behaviours and higher rates of risky behaviours during pregnancy, special care and counselling are recommended. © 2012 The Royal Society for Public Health.
Robati R.M.,Shahid Beheshti University of Medical Sciences |
Abdollahimajd F.,Shahid Beheshti University of Medical Sciences |
Robati A.M.,Bam University of Medical science
Dermatology Research and Practice | Year: 2015
Background. A prominent nasolabial fold (NLF) is a cosmetic problem. Currently, numerous therapeutic modalities are available for pronounced NLFs with variable efficacy. Objective. To determine the efficacy and safety of subcision using a hypodermic needle for the correction of the prominent NLFs and its effect on skin elasticity. Methods. Sixteen patients with prominent NLFs underwent subcision. The investigators' assessment of improvement and the patients' satisfaction were both recorded 1 and 6 months after the procedure. Also, we evaluate the skin elasticity of NLFs before and after the treatment using a sensitive biometrologic device with the measurement of cutaneous resonance running time (CRRT). Results. Thirteen (81.25%) patients showed a moderate improvement at 1st month and 13 (81.25%) patients had at least a mild improvement at 6th month. There was no persistent side effect lasting more than a few days. Mean CRRT at 1 and 6 months after the treatment was significantly higher compared to the baseline. Conclusion. Subcision may be considered effective for the correction of pronounced NLFs. However, further controlled studies with larger sample size are necessary to assess the efficacy of this technique in particular with use of more objective assessment of skin biometric characteristics. This trial is registered with IRCT201108097270N1 (registered on January 27, 2012). © 2015 R. M. Robati et al.
PubMed | Bam University of Medical science and Shahid Beheshti University of Medical Sciences
Type: | Journal: Dermatology research and practice | Year: 2016
Background. A prominent nasolabial fold (NLF) is a cosmetic problem. Currently, numerous therapeutic modalities are available for pronounced NLFs with variable efficacy. Objective. To determine the efficacy and safety of subcision using a hypodermic needle for the correction of the prominent NLFs and its effect on skin elasticity. Methods. Sixteen patients with prominent NLFs underwent subcision. The investigators assessment of improvement and the patients satisfaction were both recorded 1 and 6 months after the procedure. Also, we evaluate the skin elasticity of NLFs before and after the treatment using a sensitive biometrologic device with the measurement of cutaneous resonance running time (CRRT). Results. Thirteen (81.25%) patients showed a moderate improvement at 1st month and 13 (81.25%) patients had at least a mild improvement at 6th month. There was no persistent side effect lasting more than a few days. Mean CRRT at 1 and 6 months after the treatment was significantly higher compared to the baseline. Conclusion. Subcision may be considered effective for the correction of pronounced NLFs. However, further controlled studies with larger sample size are necessary to assess the efficacy of this technique in particular with use of more objective assessment of skin biometric characteristics. This trial is registered with IRCT201108097270N1 (registered on January 27, 2012).
PubMed | Bam University of Medical science, Sabzevar University of Medical Science, Pasteur Institute of Iran and Mazandaran University of Medical Sciences
Type: Journal Article | Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene | Year: 2016
Two important genes for controlling TB are IFN and IFNR1. However, little information exists regarding genetic susceptibility of the Iranian TB population.We investigated the single nucleotide polymorphisms (SNPs) in genes of IFN (+874 A/T) and IFNR1 (-56 C/T) and serum level of IFN and their influence on TB in patients; 300 patients with TB and 300 healthy controls were enrolled in this study. PCR-restriction fragment length polymorphism was used to identify SNPs and serum level of IFN was measured by ELISA.The allelic and the genotypic form of IFN+874 A/T SNP of the studied population were not significant (p>0.05). Allele T frequencies of IFNR1 -56 C/T promoter region in patients with pulmonary TB (PTB) or extrapulmonary TB (EPTB) were significantly greater than allele C. The -56 TT motif of IFNR1 is associated with both forms of TB (p<0.05). The serum level of IFN was significantly higher in patients with TB than in controls, but there was no significant difference between serum level of IFN and the studied genotypes (p>0.05).The cause of active TB in the patients seems to be due to the lack of effective IFN function or the lack of effective signaling connection between IFN and its receptor in presence of -56 C/T polymorphism in promoter region of IFNR1 gene.
Ahmadi B.,Kerman Medical University |
Zaherara M.,Bam University of Medical science
Journal of Kerman University of Medical Sciences | Year: 2015
Background & Aims: Celiac disease or gluten-sensitive enteropathy is a relatively uncommon digestive disease. Moreover, irritable bowel syndrome (IBS) is a common functional bowel disorder. Some IBS patients have celiac disease, with similar IBS symptoms in addition to some serious complications. The only possible treatment for this condition is changing the patients diet (gluten free diet). Given the importance of celiac disease and the similarity of its symptoms with IBS, this study aimed to determine the prevalence of celiac disease in patients with irritable bowel syndrome in Kerman, Iran. Methods: This was a cross-sectional study performed during 8 months on patients of 15-84 years of age diagnosed with IBS in Kerman in 2013. Serological test of immunoglobulin A anti-tissue transglutaminase (IgA anti tTG) was request in all IBS patients for the diagnosis of celiac disease and bulb and duodenal (second part) biopsy and pathologic findings were used for definite diagnosis in seropositive patients. Results: The study included 143 patients with irritable bowel syndrome [57 males (39.86%) and 86 females (60.14%)] with a mean age of 34.57 ± 1.24. Serological tests showed that 8 (5.59%) patients were seropositive for celiac disease and duodenal biopsy showed 4 (2.79%) patients were seropositive and (2 males (Marsh2) and 2 females (Marsh1)) were positive for serologic and pathologic celiac disease. Among these patients, 1 patient (male) had constipation–predominant IBS, and 3 patients (1 male and 2 females) had diarrhea-predominant IBS. Conclusion: This study indicated a 5.59% prevalence of positive serologic and 2.79% prevalence of positive serologic-pathologic celiac disease in patients with IBS in Kerman. This was lower in comparison with similar studies in other regions of the country. This difference may be due to the effects of demographic, genetic, and environmental factors of each region. © 2015, Kerman University of Medical Sciences. All rights reserved.
Sadeghian H.,Harvard University |
Motiei-Langroudi R.,Bam University of Medical science
Emergency Radiology | Year: 2016
Traumatic brain injury (TBI) is a significant health concern classified as mild, moderate, and severe. Although the indications to perform brain computed tomography (CT) are clear in moderate and severe cases, there still exists controversy in mild TBI (mTBI). We designed the study to evaluate the significance of distracting pain in patients with mTBI. The study population included patients with mild traumatic brain injury (GCS ≥13). Moderate and high risk factors including age <18 months or ≥60 years, moderate to severe or progressive headache, ≥2 episodes of vomiting, loss of consciousness (LOC), post-traumatic amnesia, seizure or prior antiepileptic use, alcohol intoxication, previous neurosurgical procedures, uncontrolled hypertension, anticoagulant use, presence of focal neurologic deficits, deformities in craniofacial region, and penetrating injuries were excluded. The patients were then grouped based on presence (DP+) or absence (DP−) of another organ fracture with severe pain (based on VAS). The primary outcome was any abnormal findings on brain CT scans; 330 patients were enrolled (184 DP+ and 146 DP−). Overall, two DP+ and one DP− patients had mild cerebral edema in brain CT (p > 0.99). No patients had any neurologic symptoms or signs in follow-up. Our results show that in the absence of any other risk factors, distracting pain from other organs (limbs, pelvis, and non-cervical spine) cannot be regarded as a brain CT indication in patients with mild TBI, as it is never associated with significant intracranial lesions. © 2016, American Society of Emergency Radiology.
PubMed | Kerman Medical University and Bam University of Medical science
Type: Journal Article | Journal: JPMA. The Journal of the Pakistan Medical Association | Year: 2016
Nowadays it is known that dietary imbalances are associated with non-communicable diseases which would be a major cause of worldwide deaths in 2020. This study was conducted to assess the dietary pattern of students who live in a dormitory in Kerman, Iran, based on Healthy Eating Index-2005 (HEI-2005).This cross-sectional study was conducted on 229 students who lived in the dormitory of Kerman University of Medical Science. The participants were recruited by multistage sampling. Their usual dietary intake was collected by using a valid food frequency questionnaire. The diet quality was calculated via HEI-2005. The HEI-2005 score was categorized into three groups: less than 50 (poor diet), between 50-70 (needs improvement) and more than 70 (good diet).The mean score of HEI-2005 in the present study was 64.228.98. 8.1% of the participants had poor diet, 63.4% had to improve their diet, and 28.5% enjoyed a good diet. The percent of energy intake from total fat, saturated fatty acid, solid fat and added sugar, and also sodium were significantly lower in the highest category of HEI-2005 than the lowest category. There was no significant difference in the intake of cholesterol, total vegetable and dairy products between the highest and lowest quartile categories.Majority of the participants need to improve their diet.Policy revisions and dietary interventions would require to promote diet quality and prevent non-communicable diseases in the future.
PubMed | Mashhad University of Medical Sciences, Kerman Medical University and Bam University of Medical science
Type: Journal Article | Journal: Hepatitis monthly | Year: 2016
Non-alcoholic steatohepatitis (NASH) is a progressive form of nonalcoholic fatty liver disease. Several studies suggest that pentoxifylline (PTX) can improve the disease outcome.We aimed to compare the effect of pentoxifylline with placebo on liver aminotransferases and cytokines, including interleukin 6 (IL-6), tumor necrosis factor alpha (TNF-), and interleukin 8 (IL-8) in patients with NASH.Thirty patients with NASH were included in the study, based on ultrasonography and 1.5-fold mean change from baseline serum levels of liver aminotransferases. Patients with NASH were randomized to receive 1200 mg PTX (the intervention group) or placebo (the placebo group) for 6 months. The serum levels of liver aminotransferases and cytokines were compared between the intervention and placebo groups, at various time points.The serum levels of liver aminotransferases were significantly reduced at 3 months and at 6 months, compared with baseline, in both groups. The serum levels of IL-6 were significantly decreased, in both groups, only at 6 months, compared with baseline. Compared to the placebo group, the serum level of TNF- was significantly decreased in the intervention group, at 6 months. The serum level of IL-8 was increased, in both groups, after 6 months, without reaching clinical significance. There was no significant difference in serum levels of liver aminotransferases and cytokines, between intervention and placebo groups.Decreases in the serum levels of liver aminotransferases and cytokines, in both groups, are related to low-calorie diets and exercise, rather than PTX.
PubMed | Mashhad University of Medical Sciences, Kerman Medical University and Bam University of medical science
Type: Journal Article | Journal: Clinics and research in hepatology and gastroenterology | Year: 2016
Irritable bowel syndrome (IBS) is the most prevalent functional gastrointestinal (GI) disorder, which presents with abdominal pain and changes in the bowel habits. Although the exact cause of IBS remains uncertain, some studies have shown that the inflammation and cytokine imbalance may act as potential etiological factors. The aim of our study is to compare the serum levels of interleukin 6 (IL-6), interleukin 8 (IL-8), and tumor necrosis factor-alpha (TNF-) in patients with IBS with the healthy controls. The other aim of this study is to evaluate possible association between above-mentioned cytokines and IBS subtypes.Seventy-four IBS patients diagnosed based on Rome III criteria and 75 gender and age-matched healthy controls were included in this study. Cytokines were measured in the serum using enzyme-linked immunosorbent assays (ELISA).Patients were classified into groups of IBS with diarrhea (IBS-D): 34, IBS with constipation (IBS-C): 29, and IBS with mixed symptoms (IBS-M): 11. The serum levels of IL-6, IL-8 and TNF- were significantly higher in patients with IBS as compared to controls (P<0.001). There was no difference in serum levels of cytokines based on IBS subtypes.Higher serum level of IL-6, IL-8 and TNF- in IBS suggests an important role of cytokines as immune mediators in the pathogenesis of this functional GI disorder. To understand any association between cytokines and IBS subtypes, further investigations with larger sample sizes are desired.