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Rezvani A.,Bezmialem Foundation University | Ergin O.,Ministry of Health | Karacan I.,Vakif Gureba Training and Research Hospital | Oncu M.,Bagcilar Training and Research Hospital
Spine | Year: 2012

STUDY DESIGN.: A prospective, controlled clinical study performed in a tertiary care center. OBJECTIVE.: To determine reliability and validity of low-tech measurements in assessment of range of motion (ROM) of lumbar flexion in ankylosing spondylitis (AS). SUMMARY OF BACKGROUND DATA.: ROM measurements of lumbar flexion in patients with AS and healthy subjects are evaluated using original Schober test (OST), modified Schober index (MSI), and modified-modified Schober test (MMST) and compared with radiography. METHODS.: Fifty patients with AS and 17 healthy subjects were included. A tape measure was used for measuring OST, MSI, and MMST, and goniometer was used for measuring angle of lumbar ROM on lateral radiographical views in erect position and maximal forward bending position. RESULTS.: Angle between L1 and S1 vertebrae displayed a change upon flexion by 18.2° ± 18.7° in AS group and 30.4° ± 11.1° in controls (P = 0.002). Angle between L3 and S1 vertebrae was detected to change upon flexion by 25.3° ± 25.4° in AS group and 46.7° ± 14.2° in controls (P = 0.0001). A weak correlation was observed between MSI, OST, and L1-S1 radiographical mobility measurements as (P = 0.018 and P = 0.063) and MSI, OST, and L3-S1 radiographical mobility measurements as (P = 0.009 and P = 0.024), respectively for AS. There were correlations between MSI, OST, and radiographical mobility measurements in patients with AS (r = 0.333, P = 0.018, and r = 0.363, P = 0.009, respectively). There was a correlation between OST and radiographical mobility measurements in controls (r = -0.504, P = 0.039). Intrarater reliability was determined to be excellent for OST, MSI, and MMST. CONCLUSION.: Despite excellent intrarater reliabilities for OST, MSI, and MMST, only a weak correlation could be established between OST, MSI, and MMST and radiographical analysis. MMST was found not to reflect lumbar spine angular motions. Although MSI reflected spinal mobility better than OST, both seemed to reflect lumbar spine angular motion poorly. © 2012, Lippincott Williams & Wilkins.

Basat S.O.,Bagcilar Training and Research Hospital
Journal of Craniofacial Surgery | Year: 2016

ABSTRACT: Sarcoidosis is a multisystem inflammatory disease that manifests as noncaseating granulomas, commonly in the lungs and intrathoracic lymph nodes. Subcutaneous manifestations of sarcoidosis that are caused by granulomas are referred to as specific for sarcoidosis, whereas other lesions are considered nonspecific. The authors present “sarcoidosis nodule formation on the lateral nasal osteotomy lines” in a sarcoidosis patient undergoing rhinoplasty surgery as a rare patient.Level of Evidence: V © 2016 by Mutaz B. Habal, MD.

Serefoglu E.C.,Bagcilar Training and Research Hospital
Andrologia | Year: 2016

Premature ejaculation (PE) is considered to be the most common form of male sexual dysfunction. Given that acute oral administration of d-isomer of modafinil (d-modafinil) can extend the latency to ejaculation in rats without suppressing sexual behaviour, the effects of on-demand d-modafinil treatment were examined on a 30-year-old male patient with lifelong PE. The patient was instructed to take d-modafinil 100 mg 3 h prior to the sexual relation for four times and was invited for a control visit. The patient was re-evaluated 2 weeks later. He reported that his IELT increased to 15 min. He reported heartburn and insomnia when he used d-modafinil for the first time; however, these symptoms were transient and did not recur after the initial dose. Overall, he reported considerable improvement and noted that he feels much better with the treatment. Based on this limited data, on-demand d-modafinil seems to be an effective treatment for men with lifelong PE. The side effects were transient and mild in the reported case. Further randomised clinical trials are necessary to elucidate the therapeutic concept of this drug in patients with lifelong PE. © 2016 Blackwell Verlag GmbH.

Saitz T.R.,Oregon Health And Science University | Serefoglu E.C.,Bagcilar Training and Research Hospital
Nature Reviews Urology | Year: 2015

Male sexual medicine has continued to evolve and several publications related to premature ejaculation, lower urinary tract symptoms, Peyronie's disease and testosterone replacement therapy have provided new insights in these fields. Our understanding has been revolutionized by these studies and clinical management in male sexual dysfunction has improved. © 2015 Macmillan Publishers Limited. All rights reserved.

Saitz T.R.,Oregon Health And Science University | Serefoglu E.C.,Bagcilar Training and Research Hospital
Nature Reviews Urology | Year: 2015

Over the past several years, many advances have been made in our understanding of the epidemiology, pathophysiology, and management of premature ejaculation. Newly developed definitions of premature ejaculation are now available, and our perception of the classification, prevalence, aetiological factors, and treatment options for premature ejaculation have evolved. Despite ongoing research, there remains much to be learned about all aspects of this common sexual disorder, in particular effective clinical diagnosis and treatment options. © 2015 Macmillan Publishers Limited.

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