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Lahore, Pakistan

Fahim A.,Post Graduate Medical Institute | Ilyas M.S.,Post Graduate Medical Institute | Jafari F.H.,Azra Naheed Medical College | Farzana F.,Post Graduate Medical Institute
Journal of Oral Biology and Craniofacial Research | Year: 2016

Background: Carbonated drinks are the second most consumed non-alcoholic beverages in the world after tea. The effects of these drinks on hard tissues and vital organs of the body have been proved beyond doubt. This study, however, explains the effect of these drinks on wound healing of oral epithelium. Methods: Thirty-six male Wistar rats were considered for the study. A circular wound of 3.0 mm was created on the buccal mucosa of all animals and they were divided into two groups. Animals in group 1 were fed with chow pellet and water, while those in group 2 were fed with a commercially available carbonated drink instead of water. Six animals from each group were euthanized at 0, 7, and 21 days. Wound site was histologically assessed for differences in thickness and characteristics of the regenerating epithelium between two groups. Results: There was a marked difference in the healing pattern between the two groups. Animals in group 1 showed a normal healing pattern at the end of day 21. In the group 2, the regenerated epithelium showed hyperplasia and hyperkeratosis along with acanthosis at the end of the experiment with a subsequent delayed inflammatory reaction at day 21. Conclusion: Consumption of carbonated drinks can disrupt oral wound healing. The contents in carbonated drinks have a proinflammatory action on the soft tissue. Results suggest that epithelial changes seen in experimental group 2 could be a result of constant irritation by the acidic and fizzy nature of carbonated drinks. © 2015 Craniofacial Research Foundation.


Tauseef A.,Lahore Medical and Dental College | Sabir S.,Khawaja Muhammad Safdar Medical College | Akmal A.,Lahore Medical and Dental College | Sajjad S.,Azra Naheed Medical College | Zulfiqar S.,Shaikh Zayed PGMI
Journal of the College of Physicians and Surgeons Pakistan | Year: 2016

Objective: To evaluate the plasma interleukin-10 (IL-10) levels in patients suffering from dengue hemorrhagic fever between 4 to 7 days of onset of disease and 24 hours after the first sample, to find out the association of plasma IL-10 levels with the outcome. Study Design: Analytical study. Place and Duration of Study: All major hospitals of Lahore, Pakistan, from August to November 2012. Methodology: Participants included 50 registered patients of dengue hemorrhagic fever (DHF) aged between 15 - 50 years. Plasma IL-10 concentrations were measured on above stated day. Outcome was described as recovery and shock. Platelet count and hematocrit percentages were also recorded. Statistical analyses were done using SPSS version 19. A p-value ≤ 0.05 was considered significant. Results: Plasma IL-10 levels were found to be raised in DHF patients and were associated with fatal outcome (p=0.004). In recovered DHF patients, plasma IL-10 levels decreased after 24 hours (mean 26.54 ±16.03 pg/ml) as compared to admission time (mean 74.39 ±61.69 pg/ml) but in case of DHF patients suffering from shock, plasma IL-10 was found to be higher after 24 hours (mean 87.69 ±7.77 pg/ml) as compared to levels at admission time (mean 42.56 ±28.09 pg/ml). ROC curve analysis revealed a change (30 units pg/ml) of plasma IL-10 concentration, within 24 hours of admission, raised from the base line to be 105 times more critical for shock in DHF patients (100% sensitivity and 71.4% specificity, p < 0.001). Conclusion: Elevated plasma IL-10 is a potential predictor of disease severity and fatal outcome in DHF patients.


Nayyar U.,Institute of Public Health | Dar U.F.,Institute of Public Health | Latif M.Z.,Azra Naheed Medical College | Haider R.,Institute of Public Health | And 2 more authors.
Pakistan Journal of Medical and Health Sciences | Year: 2013

Aim: To find out knowledge of Dengue fever among university students, studying different courses. Duration: Study was conducted during month of June, July and August, 2011. Methods: It was ac cross-sectional study conducted on 374 students studying at intermediate bachelors and master level in University of Gujrat. Pretested questioners were used to collect primary data. Composite cumulative scores were used to determine knowledge about dengue fever. Students enrolled in engineering, medical, basic sciences, It & business administration and social sciences were major groups of study. Data was entered and analysed in SPSS 17. Results: Response was collected from 374(53.5% females & 36.5% males participants. Mean age with SD was 21.3±1.72. IT & business administration students scored the highest in knowledge. No considerable difference seen among high and low socio-economic groups (p=0.06) Conclusion: Good knowledge in IT students among different groups (p=0.000), support the fact that internet is strong source of information and helpful tool for raising awareness amongst general public. High knowledge of preventive measures is not depicted in practice and needs awareness strategies towards ensuring implementation of preventive measures.


Latif M.Z.,Azra Naheed Medical College | Hussain I.,Services Institute of Medical science | Nizami R.,University of Management and Technology | Farooq U.,Institute of Public Health | Riaz H.,Health Care Diagnostics and Research Center
Pakistan Journal of Medical and Health Sciences | Year: 2013

Aim: To find out the benefits of Private Public Mix Working Model of a Teaching Hospital for the organizations and end users. Study design: Cross sectional Survey Methods: The study was conducted at Islamic International Medical College (IIMC) and Pakistan Railway Hospital (PRH) Rawalpindi. Retrospective data was collected on a semi structured, pre tested questionnaire from the records of PRH. The benefits of PPM working model were assessed using variables like training of students, hiring of academic staff, availability and utilization of different services. Results: 600 undergraduate, 7 postgraduate and 26 nursing students were being trained after implementation of model. Academic staff increased from 17 to 127 doctors. Number of departments increased from 4 to 15 and range of laboratory test increased from 16 to 92. Outpatient and indoor flow of patients increased up to 500% after the intervention. There are evident benefits for both the organizations and end users through this private public mix working model.


Sattar S.A.,Azra Naheed Medical College | Hameed M.N.,Shalamar Medical and Dental College | Tayyba A.,Azra Naheed Medical College
Pakistan Paediatric Journal | Year: 2012

Objective: A case-control clinical trial was conducted to determine the association of iron deficiency and first febrile seizure in children of aged 6 - 60 months. Methods: Hematological parameters for iron status including HB, MCV, MCHC and plasma ferritin level were determined in 90 patients presenting with first febrile seizure. Age and sex matched 90 children admitted for febrile illnesses without seizures were taken as controls and same markers were compared in two groups. Results: The most significant factors which influenced first febrile seizure were HB level, MCV and Serum Ferritin level. Conclusion: Iron deficiency is significantly associated with occurrence of first febrile seizure in children. Abbreviations: ID - Iron Deficiency, FS - Febrile Seizures. FFS - First Febrile Seizure, HB - Hemoglobin, MCV - Mean Corpuscular Volume, MCHC - Mean Corpuscular Hemoglobin Concentration, PF - Plasma Ferritin, CNS - Central Nervous System, IQR - Interquartile range.

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