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Villupuram district, India

Mohammed Moideen M.,Azath street | Varghese R.,Azath street | Krishna Kumar E.,Azath street | Dhanapal C.K.,Azath street
Research Journal of Pharmaceutical, Biological and Chemical Sciences | Year: 2011

The study was carried out to evaluate the wound healing activity of ethanolic extract of Hemidesmus indicus leaves in rats. Twenty four healthy animals of Wister strain were assigned to four groups, containing six animals each. Group 1 (positive control) was provided with nitrofurantoin ointment, group 2 (solvent control) with 70% ethanol, group 3 (test dose I) with 5% w/w Hemidesmus indicus ointment and group 4 (test dose II) with 10% w/w Hemidesmus indicus ointment. The total exposure of the study was 16 days. The groups were compared for the percentage of wound healing. It was observed that the group treated with nitrofurantoin ointment showed an increase in the rate and percentage of wound contraction and period of epithelization compared to the ethanol treated group. The alcoholic extract of Hemidesmus indicus (5% and 10% ointment) increased rate of wound contraction and period of epithelization than solvent and control groups. Comparison between test dose I and test dose II showed that the percentage and rate of wound healing was increased at test dose I than test dose II. The study evaluated the wound healing activity of the alcoholic extract of Hemidesmus indicus and identified it to possess significant wound healing activity. Source


Moideen M.M.,Azath street | Varghese R.,Azath street | Ramakrishnan P.,Azath street | Dhanapal C.K.,Azath street
Research Journal of Pharmaceutical, Biological and Chemical Sciences | Year: 2011

All over the world, obesity has almost reached epidemic proportions and India is not far behind. Obesity and overweight are dramatically on the rise particularly in urban settings which have been reported to pose a risk factor for diseases such as diabetes, hypertension etc. To make people aware of this fact counseling may play an important role hence, a randomised prospective study was carried out to evaluate the effectiveness of patient education in overweight and obese patients on weight reduction in an urban community pharmacy in India. A total of 100 subjects who visited the pharmacy were recruited and counseling was provided on diet, physical activity and behavioural modifications. Statistical analysis of data collected revealed that mean levels of body mass index before and after intervention in male and female population after three months projected a 't' value of 11.80 and 3.08, respectively which was found to be statistically significant at P=0.001. Similarly, the mean levels of waist circumference were also found to be significant at P=0.001 in both male and female population. It was concluded from the study that patient education provided by the pharmacist helped in decreasing total body weight, waist circumference and risk of weight related complications. Source

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