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Meenakshi T.G.,Y Y D Government First Grade College | Shylajakumari J.,AVK College for Women | Devarajegowda H.C.,AVK College for Women | Devarajegowda H.C.,University of Mysore | And 2 more authors.
Acta Crystallographica Section E: Structure Reports Online | Year: 2013

In the title compound, C15H16ClNO2S 2, the 2H-chromene ring system is nearly planar, with a maximum deviation of 0.023 (2) Å. In the crystal, C - H⋯O hydrogen bonds give R 2 1(7) motifs, which generate [100] chains. C - H⋯π and π-π interactions between chromene moieties [shortest ring centroid-centroid distance = 3.6199 (13) Å] consolidate the packing. © 2013 Meenakshi et al. Source


Ambekar S.P.,Karnatak University | Devarajegowda H.C.,University of Mysore | Shylajakumari J.,AVK College for Women | Kumar K.M.,Karnatak University | Kotresh O.,Karnatak University
Acta Crystallographica Section E: Structure Reports Online | Year: 2013

In the title compound, C15H11BrO3, the dihedral angle between the benzene rings is 72.59 (6)°. In the crystal, pairs of C - H⋯π contacts form inversion dimers. Additional C - H⋯O hydrogen bonds generate R 2 1(6) ring motifs and stack these dimers along the b axis. Short intermolecular Br⋯O contacts of 3.254 (3) Å are also observed and link the stacks into a three-dimensional network. © 2013 Ambekar et al. Source


Lingaraju D.P.,AVK College for Women | Sudarshana M.S.,University of Mysore
International Journal of Pharma and Bio Sciences | Year: 2014

The purpose of present work is to study antimicrobial activity and medicinally active principles present in different solvent extracts obtained from roots of Heracleum rigens. The active principles were isolated by Soxhlet extractor using petroleum ether, chloroform, ethyl acetate and methanol and identified by preliminary phytochemical test. The results of analyses of each extract confirm the active substances were alkaloids, sterols, triterpenes, glycosides and flavonoids. The antimicrobial tests of isolated substances were performed against bacteria- Bacillus subtilis, Staphylococcus aureus, Escherichia coli, Pseudomons aeruginosa, and a fungus Candida albicans. The results revealed that ethyl acetate extract has significant antimicrobial activities. Heracleum rigens revealed the highest antibacterial activity at a minimum inhibitory concentration (6.25μg/ml) against P.aeruginosa and highest antifungal activity at a MIC (1.56μg/ml) against C.albicans. The results provide justification for the use of the H.rigens in folk medicine to treat various infectious diseases. Source


Vinduvahini M.,Sri D Devaraja Urs Government First Grade College | Jeyaseelan S.,University of Mysore | Shylajakumari J.,AVK College for Women | Revanasiddappa H.D.,University of Mysore | Devaru V.B.,P.A. College
Acta Crystallographica Section E: Structure Reports Online | Year: 2012

In the title compound, C 23H 26FN 3O 6S, the two terminal aromatic rings form a dihedral angle of 49.26(12)°. The cyclohexane ring adopts a chair conformation and the fivemembered ring is essentially planar, with a maximum deviation from planarity of 0.0456(19) Å. The dihedral angles between the five-membered ring and the methoxybenzene and fluorobenzene rings are 33.56(11) and 81.94(12)°, respectively. The crystal structure displays N-H···O hydrogen bonds as well as weak intermolecular C-H···O interactions. Source


Sreenivasa S.,Tumkur University | Nanjundaswamy M.S.,AVK College for Women | Madankumar S.,University of Mysore | Lokanath N.K.,University of Mysore | And 2 more authors.
Acta Crystallographica Section E: Structure Reports Online | Year: 2014

In the title compound, C14H13NO4S, the dihedral angle between the aromatic rings is 69.81(1)°; the dihedral angle between the planes defined by the S - N - C=O segment of the central chain and the sulfonyl benzene ring is 74.91(1)°. In the crystal, the molecules are linked by weak N - HO hydrogen bonds into C(4) chains running along [100]. The molecules in adjacent chains are linked by weak C - HO interactions, generating R 22 (16) dimeric pairs. Weak C - Hπ interactions connect the double chains into (001) sheets. © Sreenivasa et al. 2014. Source

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