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Apeldoorn, Netherlands

Avans University of Applied science is a high-ranked Dutch vocational university. It is located in three cities: Breda, 's-Hertogenbosch, and Tilburg. The school has 25,000 students studying 40 courses in 18 institutes. There are 2,300 employees.Avans University of Applied science itself was founded on January 1, 2004 as a union of Hogeschool 's-Hertogenbosch and Hogeschool Brabant in Tilburg, Breda, and Etten-Leur. Hogeschool Brabant itself was a union from 1988 of Hogeschool West-Brabant and Hogeschool Midden-Brabant . The oldest branch of Avans University of Applied science is the Kunstacademie in 's-Hertogenbosch, which was founded on October 1, 1812. Wikipedia.

Neven L.,AVANS University of Applied Sciences | Walker G.,Lancaster University | Brown S.,Lancaster University
Energy Policy | Year: 2015

The use of more sustainable thermal technologies is a policy imperative across the UK building stock. However, not all building uses provide the same opportunities for technology uptake as others. Care homes for older people have characteristics which in technical and economic terms suggest that they might be particularly appropriate for the implementation of more sustainable thermal technologies. They have comparatively high demands for space heating and hot water often sustained on a 24/7 basis. However there are many considerations, both generic and contextual, that will typically play into processes of technology uptake. Through qualitative research in six case study homes, focused on management and staff perspectives and experiences, we explore the degree to which there might be a productive alignment between care home operation and the use of sustainable thermal technologies. Two key themes emerge focused on business considerations and the importance of avoiding risk and damage to reputation; and the ways in which different thermal technologies are relevant to and can potentially impact on care practices. We conclude that despite potential benefits the sector could remain rather resistant to sustainability innovations. We suggest therefore areas in which productive action and further research could be undertaken. © 2014.

Mohammadi T.,University Utrecht | Van Dam V.,University Utrecht | Sijbrandi R.,University Utrecht | Sijbrandi R.,AVANS University of Applied Sciences | And 7 more authors.
EMBO Journal | Year: 2011

Bacterial cell growth necessitates synthesis of peptidoglycan. Assembly of this major constituent of the bacterial cell wall is a multistep process starting in the cytoplasm and ending in the exterior cell surface. The intracellular part of the pathway results in the production of the membrane-anchored cell wall precursor, Lipid II. After synthesis this lipid intermediate is translocated across the cell membrane. The translocation (flipping) step of Lipid II was demonstrated to require a specific protein (flippase). Here, we show that the integral membrane protein FtsW, an essential protein of the bacterial division machinery, is a transporter of the lipid-linked peptidoglycan precursors across the cytoplasmic membrane. Using Escherichia coli membrane vesicles we found that transport of Lipid II requires the presence of FtsW, and purified FtsW induced the transbilayer movement of Lipid II in model membranes. This study provides the first biochemical evidence for the involvement of an essential protein in the transport of lipid-linked cell wall precursors across biogenic membranes. © 2011 European Molecular Biology Organization | All Rights Reserved.

Van Dael M.,Hasselt University | Van Passel S.,Hasselt University | Pelkmans L.,Flemish Institute for Technological Research | Guisson R.,Flemish Institute for Technological Research | And 4 more authors.
Applied Energy | Year: 2013

Biomass as a renewable energy source has many advantages and is therefore recognized as one of the main renewable energy sources to be deployed in order to attain the target of 20% renewable energy use of final energy consumption by 2020 in Europe. In this paper the concept of a biomass Energy Conversion Park (ECP) is introduced. A biomass ECP can be defined as a synergetic, multi-dimensional biomass conversion site with a highly integrated set of conversion technologies in which a multitude of regionally available biomass (residue) sources are converted into energy and materials. A techno-economic assessment is performed on a case study in the Netherlands to illustrate the concept and to comparatively assess the highly integrated system with two mono-dimensional models. The three evaluated models consist of (1) digestion of the organic fraction of municipal solid waste, (2) co-digestion of manure and co-substrates, and (3) integration. From a socio-economic point of view it can be concluded that it is economically and energetically more interesting to invest in the integrated model than in two separate models. The integration is economically feasible and environmental benefits can be realized. For example, the integrated model allows the implementation of a co-digester. Unmanaged manure would otherwise represent a constant pollution risk. However, from an investor's standpoint one should firstly invest in the municipal solid waste digester since the net present value (NPV) of this mono-dimensional model is higher than that of the multi-dimensional model. A sensitivity analysis is performed to identify the most influencing parameters. Our results are of interest for companies involved in the conversion of biomass. The conclusions are useful for policy makers when deciding on policy instruments concerning manure processing or biogas production. © 2012 Elsevier Ltd.

Zoeteman B.C.J.,University of Tilburg | Krikke H.R.,University of Tilburg | Venselaar J.,AVANS University of Applied Sciences
International Journal of Advanced Manufacturing Technology | Year: 2010

This paper explores the present and future magnitude of global waste of electrical and electronic equipment flows, and investigates desirable changes in these flows from a sustainable development point of view. Quantitative estimates of present and future e-waste flows between global regions, generating, and processing waste are presented and their driving forces are analyzed. Global e-waste production by households exceeded an annual amount of 20 million tons in 2005. Domestic e-waste generation in China has already climbed dramatically, now equalling the amount generated in Japan. China is second in the world after the USA in landfilling and incineration of ewaste residues. Absolute volumes of recycled e-waste are largest in the EU, followed by Japan. After a period characterized by national disposal practices, a period of global low-level recovery practices has emerged. The paper analyzes exogenous factors, including legislating promoting extended producer responsibility, which are favoring as a next step regionalizing of (reverse) supply chains. Examples on a business level are discussed and critical success factors for applying regional high-level recovery are identified. The analysis shows that in the coming decades, two options will compete on a global scale: (1) a further expansion of the present low-level recovery system of ewaste recycling, and (2) a regional approach with higher level recovery applications. The authors argue that putting businesses, more specifically, the original equipment manufacturers, instead of legislators in the driver seat, will strengthen the opportunities for high-level recovery. © The Author(s) 2009.

Gobbens R.J.J.,AVANS University of Applied Sciences | Luijkx K.G.,University of Tilburg | Wijnen-Sponselee M.T.,AVANS University of Applied Sciences | Schols J.M.G.A.,Maastricht University
Journal of Nutrition, Health and Aging | Year: 2010

Objectives: Most conceptual and operational definitions of frailty place heavy emphasis on the physical problems encountered by older people. The accompanying models are based largely on a medical model. An integral approach is almost never adopted. This study aims to develop both an integral operational definition of frailty and an integral conceptual model of frailty. Design: In order to achieve these aims, a thorough literature search was performed on components of operational definitions and models of frailty. In addition, experts (N=17) were consulted during two expert meetings. Results: There was consensus among the experts on the inclusion of the following components in the operational definition of frailty: strength, balance, nutrition, endurance, mobility, physical activity and cognition. Some respondents indicated that they would wish to add components from the psychological or social domain. Supported by results from the literature search, a new integral operational definition of frailty was developed. This operational definition lies at the heart of an integral conceptual working model of frailty. This model expresses the relationships between three domains of frailty, adverse outcomes such as disability and the determinants. Conclusion: The model should be able to serve as a basis for further scientific research on frailty. The model also provides a framework for the development of a measurement instrument which can be used for the identification of frail elderly persons.

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