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Vellore, India

Basha S.K.,C Abdul Hakeem College | Kumari V.S.,Auxilium College
Asian Pacific Journal of Tropical Disease | Year: 2012

Objective: To evaluate the glucose uptake of (antidiabetic activity) crude n-hexane, ethanol, ethanol and aqueous leaf extracts of P. guajava. Methods: P. guajava leaf extracts were subjected to inhibitory effect of glucose utilization using specific standard in vitro procedure. Results: Results in four different leaf extracts revealed that, the methanol extract at a concentration of 50g plant extract/l was found to be more potent than other extracts with the lowest mean glucose concentration of 201+1.69 mg/dl at the end of 27 hrs. Conclusions: The present findings suggest that, the methanolic extract showed a significant inhibitory effect on glucose diffusion in vitro thus validating the traditional claim of the plant. © 2012 Asian Pacific Tropical Medicine Press. Source

Agilandeswari K.,Auxilium College | Kumar A.R.,Vellore Institute of Technology
Journal of Rare Earths | Year: 2015

The great deal of novel rare earth based semiconducting lanthanum barium copper oxide La3Ba3Cu6O14 (LBC-336) were synthesized by low temperature molten salt synthesis (MSS) due to "dissolution precipitation mechanism". Here, we reported one pot synthesis of product by direct precipitation from a molten KOH-NaOH mixture at 450 °C and single phase La3Ba3Cu6O14 with tetragonal crystal system. The particle size of 140-200 nm were observed in both PXRD pattern and HRSEM micrographs and it showed a cubic morphology. The semiconducting nature was extracted from various parameters like optical band gap (1.8 eV), AC conductivity (0.70 eV), DC conductivity (0.70 eV), and also Hall effect parameters like the charge carrier concentration values n=6.0×1026 m-3 and it proved as a p-type semiconductor. The electrical phase trasition temperature from ferroelectric to antiferroelectric system (Tm=420 K) and anti-ferroelectric - paraelectric system (depolarization temperature Td=673 K) which attributed to the space charge polarization contributed to the conduction mechanism. The magnetic phase transitions were from ferromagnetic to ferrimagnetic system (Curie temperature (Tc=70 K)) and it led to soft magnetic material and also held good for superconductor application upto 70 K. © 2015 The Chinese Society of Rare Earths. Source

Kumari V.S.,Auxilium College | Basha S.K.,C Abdul Hakeem College | Sudha P.N.,D K M College
Polymer Bulletin | Year: 2012

Chitosan/poly(vinyl alcohol)/methylcellulose (CS/PVA/MC) ternary blend was prepared and chemically cross-linked with glutaraldehyde. The prepared ternary blends were characterized by Fourier transform infrared spectroscopy (FTIR), Thermogravimetric analysis (TGA), and X-ray diffraction (XRD). The FTIR results showed that the strong intermolecular hydrogen bonds took place between CS and PVA. TGA showed the thermostability of the blend is enhanced by glutaraldehyde as crosslink agent. Results of XRD indicated that the relative crystalline of pure CS film was reduced when the polymeric network was reticulated by glutaraldehyde. Finally, the results of scanning electron microscopy (SEM) indicated that the morphology of the blend is rough and heterogenous, further it confirms the interaction between the functional groups of the blend components. © Springer-Verlag 2011. Source

Kabeerdoss J.,Christian Medical College | Shobana Devi R.,Christian Medical College | Regina Mary R.,Auxilium College | Ramakrishna B.S.,Christian Medical College
British Journal of Nutrition | Year: 2012

The effect of vegetarian diets on faecal microbiota has been explored largely through culture-based techniques. The present study compared the faecal microbiota of vegetarian and omnivorous young women in southern India. Faecal samples were obtained from thirty-two lacto-vegetarian and twenty-four omnivorous young adult women from a similar social and economic background. Macronutrient intake and anthropometric data were collected. Faecal microbiota of interest was quantified by real-time PCR with SYBR Green using primers targeting 16S rRNA genes of groups, including: Clostridium coccoides group (Clostridium cluster XIVa), Roseburia spp.-Eubacterium rectale, Bacteroides-Prevotella group, Bifidobacterium genus, Lactobacillus group, Clostridium leptum group (Clostridium cluster IV), Faecalibacterium prausnitzii, Ruminococcus productus-C. coccoides, Butyrivibrio, Enterococcus species and Enterobacteriaceae. The groups were matched for age, socio-economic score and anthropometric indices. Intake of energy, complex carbohydrates and Ca were significantly higher in the omnivorous group. The faecal microbiota of the omnivorous group was enriched with Clostridium cluster XIVa bacteria, specifically Roseburia-E. rectale. The relative proportions of other microbial communities were similar in both groups. The butyryl-CoA CoA-transferase gene, associated with microbial butyrate production, was present in greater amounts in the faeces of omnivores, and the levels were highly correlated with Clostridium cluster XIVa and Roseburia-E. rectale abundance and to a lesser extent with Clostridium leptum and F. prausnitzii abundance and with crude fibre intake. Omnivores had an increased relative abundance of Clostridium cluster XIVa bacteria and butyryl-CoA CoA-transferase gene compared with vegetarians, but we were unable to identify the components of the diet responsible for this difference. © 2011 The Authors. Source

Kanimozhi K.,Auxilium College | Khaleel Basha S.,C Abdul Hakeem College | Sugantha Kumari V.,Auxilium College
Materials Science and Engineering C | Year: 2016

Biomimetic porous scaffold chitosan/poly(vinyl alcohol) CS/PVA containing various amounts of methylcellulose (MC) (25%, 50% and 75%) incorporated in CS/PVA blend was successfully produced by a freeze drying method in the present study. The composite porous scaffold membranes were characterized by infrared spectroscopy (FTIR), X-ray diffraction (XRD), thermogravimetric analysis (TGA), differential scanning calorimetry (DSC), scanning electron microscopy (SEM), swelling degree, porosity, degradation of films in Hank's solution and the mechanical properties. Besides these characterizations, the antibacterial activity of the prepared scaffolds was tested, toward the bacterial species Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli). FTIR, XRD and DSC demonstrated that there was strong intermolecular hydrogen bonding between the molecules of CS/PVA and MC. The crystalline microstructure of the scaffold membranes was not well developed. SEM images showed that the morphology and diameter of the scaffolds were mainly affected by the weight ratio of MC. By increasing the MC content in the hybrid scaffolds, their swelling capacity and porosity increased. The mechanical properties of these scaffolds in dry and swollen state were greatly improved with high swelling ratio. The elasticity of films was also significantly improved by the incorporation of MC, and the scaffolds could also bear a relative high tensile strength. These findings suggested that the developed scaffold possess the prerequisites and can be used as a scaffold for tissue engineering. © 2015 Elsevier B.V. All rights reserved. Source

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