Santo Domingo, Dominican Republic

Autonomous University of Santo Domingo
Santo Domingo, Dominican Republic

See also Universidad Santo Tomás de AquinoThe Universidad Autónoma de Santo Domingo is the public university system in the Dominican Republic with its flagship campus in the Ciudad Universitaria of Santo Domingo and with regional campuses in many cities of the Republic. It was reopened and renamed in 1914, replacing the former Universidad Santo Tomás de Aquino, the first university of the Western Hemisphere , which was founded unofficially by a Papal bull in 1538, officially by royal decree in 1558, and closed in 1832.In structure, the school followed the model of the University of Alcalá de Henares. The university organized its offerings into four schools: Medicine, Law, Theology, and the Arts. Today, the University has expanded to eight schools: Humanities, the Arts, Law and Political Science, Health science, Economics and Social science, Science, Engineering and Architecture, and Agricultural science. Wikipedia.

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Nina Estrella R.E.,Autonomous University of Santo Domingo | Landa A.I.,National University of Cuyo | Lafuente J.V.,University of the Basque Country | Gargiulo P.A.,National University of Cuyo
Acta Poloniae Pharmaceutica - Drug Research | Year: 2014

Depression in menopausal women has been widely described for many years ago, and is related to hormonal decrease, mainly estrogens. The use of soy has been proposed as a possible coadjutant alternative to treat menopausal depressive disorder. In the present pilot clinical trial the effect of soybean, antidepressants and the association of soybean with antidepressants was studied in 40 depressive menopausal women for three months. Patients were divided in four groups of 10 women: fluoxetine (10 mg), soybean (100 mg), sertraline (50 mg), and sertraline (50 mg) plus soybean (100 mg). The Hamilton and Zung Depression Scales were used to measure the treatment effects. Values at the beginning and at the end of the study were compared. In all cases a significant difference was observed when the treated groups were compared vs. their untreated situation in both scales (p < 0.001). When a comparison between pre- minus post-treatment Zung scale scores was done, the effect induced by the association of sertraline and soybean was significantly higher than the other groups (p < 0.05). These effects were also seen using the Hamilton scale scores, showing significant differences between the association vs. soybean (p < 0.05) and setraline (p < 0.05) groups, but not vs. fluoxetine group. We conclude that soybean has an antidepressant effect per se, and the association of soybean and antidepressants increases their effects.

Gutierrez-Cepeda A.,University of La Laguna | Gutierrez-Cepeda A.,Autonomous University of Santo Domingo | Hernandez Daranas A.,University of La Laguna | Fernandez J.J.,University of La Laguna | And 2 more authors.
Marine Drugs | Year: 2014

Five-membered rings are of particular interest, due to their presence in some of the most common molecules in chemistry and biology. Despite their apparent simplicity, the structural resolution of these rings is complex, due to their inherent conformational flexibility. Here, we describe an application of a recently reported simple and efficient NMR protocol based on the measurement of spin-spin coupling constants to achieve the challenging relative configurations of five new halogenated C15 tetrahydrofuranyl- acetogenins, marilzafurollenes A-D (1-4) and 12-acetoxy-marilzafurenyne (5), isolated from the red alga, Laurencia marilzae. Although DFT chemical shift calculations were used to connect remote stereocenters, the NMR-based approach seems advantageous over computational techniques in this context, as the presence of halogens may interfere with reliable calculations. © 2014 by the authors; licensee MDPI.

Shuaib W.,Emory University | Shuaib W.,Hospital General Of La Plaza Of Salud | Acevedo J.N.,Autonomous University of Santo Domingo | Khan M.S.,Dow University of Health Sciences | And 2 more authors.
American Journal of Emergency Medicine | Year: 2015

Introduction Our objective was to identify trends and examine the characteristics of the top 100 cited articles in emergency medicine (EM) journals. Methods Scopus Library database was queried to determine the citations of the top 100 EM articles. A second database (Google Scholar) was used to gather the following information: number of authors, publication year, journal name, impact factor, country of origin, and article type (original article, review article, conference paper, or editorial). The top 100 cited articles were selected and analyzed by 2 independent investigators. Results We identified 100 top-cited articles published in 6 EM journals, led by Annals of Emergency Medicine (65) and American Journal of Emergency Medicine (15). All top-cited articles were published between 1980 and 2009. The common areas of study were categorized as cardiovascular medicine, emergency department administration, toxicology, pain medicine, pediatrics, traumatology, and resuscitation. A statistically significant association was found between the journal impact factor and the number of top 100 cited articles (P <.005). Conclusion The top-cited articles published in EM journals help us recognize the quality of the works, discoveries, and trends steering EM. Our analysis provides an insight to the prevalent areas of study being cited within our field of practice. © 2015 Elsevier Inc.

Stevens G.A.,World Health Organization | Bennett J.E.,Imperial College London | Hennocq Q.,Imperial College London | Lu Y.,Harvard University | And 16 more authors.
The Lancet Global Health | Year: 2015

Background: Vitamin A deficiency is a risk factor for blindness and for mortality from measles and diarrhoea in children aged 6-59 months. We aimed to estimate trends in the prevalence of vitamin A deficiency between 1991 and 2013 and its mortality burden in low-income and middle-income countries. Methods: We collated 134 population-representative data sources from 83 countries with measured serum retinol concentration data. We used a Bayesian hierarchical model to estimate the prevalence of vitamin A deficiency, defined as a serum retinol concentration lower than 0·70 μmol/L. We estimated the relative risks (RRs) for the effects of vitamin A deficiency on mortality from measles and diarrhoea by pooling effect sizes from randomised trials of vitamin A supplementation. We used information about prevalences of deficiency, RRs, and number of cause-specific child deaths to estimate deaths attributable to vitamin A deficiency. All analyses included a systematic quantification of uncertainty. Findings: In 1991, 39% (95% credible interval 27-52) of children aged 6-59 months in low-income and middle-income countries were vitamin A deficient. In 2013, the prevalence of deficiency was 29% (17-42; posterior probability [PP] of being a true decline=0·81). Vitamin A deficiency significantly declined in east and southeast Asia and Oceania from 42% (19-70) to 6% (1-16; PP > 0·99); a decline in Latin America and the Caribbean from 21% (11-33) to 11% (4-23; PP=0·89) also occurred. In 2013, the prevalence of deficiency was highest in sub-Saharan Africa (48%; 25-75) and south Asia (44%; 13-79). 94500 (54200-146800) deaths from diarrhoea and 11200 (4300-20500) deaths from measles were attributable to vitamin A deficiency in 2013, which accounted for 1·7% (1·0-2·6) of all deaths in children younger than 5 years in low-income and middle-income countries. More than 95% of these deaths occurred in sub-Saharan Africa and south Asia. Interpretation: Vitamin A deficiency remains prevalent in south Asia and sub-Saharan Africa. Deaths attributable to this deficiency have decreased over time worldwide, and have been almost eliminated in regions other than south Asia and sub-Saharan Africa. This new evidence for both prevalence and absolute burden of vitamin A deficiency should be used to reconsider, and possibly revise, the list of priority countries for high-dose vitamin A supplementation such that a country's priority status takes into account both the prevalence of deficiency and the expected mortality benefits of supplementation. Fundin: Bill & Melinda Gates Foundation, Grand Challenges Canada, UK Medical Research Council. © 2015 World Health Organization.

Rosenberger A.L.,Brooklyn College | Rosenberger A.L.,City University of New York | Rosenberger A.L.,American Museum of Natural History | Cooke S.B.,City University of New York | And 4 more authors.
Proceedings of the Royal Society B: Biological Sciences | Year: 2011

The nearly pristine remains of Antillothrix bernensis, a capuchin-sized (Cebus) extinct platyrrhine from the Dominican Republic, have been found submerged in an underwater cave. This represents the first specimen of an extinct Caribbean primate with diagnostic craniodental and skeletal parts in association, only the second example of a skull from the region, and one of the most complete specimens of a fossil platyrrhine cranium yet discovered. Cranially, it closely resembles living cebines but is more conservative. Dentally, it is less bunodont and more primitive than Cebus, with crowns resembling Saimiri (squirrel monkeys) and one of the oldest definitive cebines, the late Early Miocene Killikaike blakei from Argentina. The tricuspid second molar also resembles the enigmatic marmosets and tamarins, whose origins continue to present a major gap in knowledge of primate evolution. While the femur is oddly short and stout, the ulna, though more robust, compares well with Cebus. As a member of the cebid clade, Antillothrix demonstrates that insular Caribbean monkeys are not monophyletically related and may not be the product of a single colonizing event. Antillothrix bernensis is an intriguing mosaic whose primitive characters are consistent with an early origin, possibly antedating the assembly of the modern primate fauna in greater Amazonia during the La Venta horizon. While most Greater Antillean primate specimens are quite young geologically, this vanished radiation, known from Cuba (Paralouatta)and Jamaica (Xenothrix) as well as Hispaniola, appears to be composed of long-lived lineages like several other mainland clades. © 2010 The Royal Society.

Velev J.P.,University of Puerto Rico at San Juan | Velev J.P.,University of Nebraska - Lincoln | Lopez-Encarnacion J.M.,University of Puerto Rico at San Juan | Lopez-Encarnacion J.M.,Autonomous University of Santo Domingo | And 2 more authors.
Physical Review B - Condensed Matter and Materials Physics | Year: 2012

We perform first-principles calculations based on density functional theory of the spin-resolved conductance of poly(vinylidene fluoride)- (PVDF) based multiferroic tunnel junctions (MFTJs). We consider Co/PVDF/O/Co (0001) MFTJs with one oxidized interface, representing the different experimental growth conditions for the two interfaces. We demonstrate that this natural asymmetry leads to multiple resistance states associated with different magnetization configurations of the electrodes and ferroelectric polarization orientations of the barrier. Our results indicate very high tunability of the tunneling magnetoresistance and electroresistance effects, which could be useful for logic and memory applications. © 2012 American Physical Society.

Lopez-Encarnacion J.M.,University of Puerto Rico at San Juan | Lopez-Encarnacion J.M.,Autonomous University of Santo Domingo | Burton J.D.,University of Nebraska - Lincoln | Tsymbal E.Y.,University of Nebraska - Lincoln | And 2 more authors.
Nano Letters | Year: 2011

Organic materials are promising for applications in spintronics due to their long spin-relaxation times in addition to their chemical flexibility and relatively low production costs. Most studies of organic materials for spintronics focus on nonpolar dielectrics or semiconductors, serving as passive elements in spin transport devices. Here, we demonstrate that employing organic ferroelectrics, such as poly(vinylidene fluoride) (PVDF), as barriers in magnetic tunnel junctions (MTJs) allows new functionality in controlling the tunneling spin polarization via the ferroelectric polarization of the barrier. Using first-principles methods based on density functional theory we investigate the spin-resolved conductance of Co/PVDF/Co and Co/PVDF/Fe/Co MTJs as model systems. We show that these tunnel junctions exhibit multiple resistance states associated with different magnetization configurations of the electrodes and ferroelectric polarization orientations of the barrier. Our results indicate that organic ferroelectrics may open a new and promising route in organic spintronics with implications for low-power electronics and nonvolatile data storage. © 2010 American Chemical Society.

Padilla M.B.,University of Michigan | Reyes A.M.,University of Michigan | Connolly M.,University of Michigan | Natsui S.,Autonomous University of Santo Domingo | And 2 more authors.
Health Policy and Planning | Year: 2012

Background The Caribbean has the highest prevalence rates of HIV/AIDS outside sub-Saharan Africa, and a broad literature suggests an ecological association between tourism areas and sexual vulnerability. Tourism employees have been shown to engage in high rates of sexual risk behaviours. Nevertheless, no large-scale or sustained HIV prevention interventions have been conducted within the tourism industry. Policy barriers and resources are under-studied.Methods In order to identify the policy barriers and resources for HIV prevention in the tourism sector, our research used a participatory approach involving a multisectoral coalition of representatives from the tourism industry, government, public health and civil society in the Dominican Republic. We conducted 39 in-depth semi-structured interviews with policy makers throughout the country focusing on: prior experiences with HIV prevention policies and programmes in the tourism sector; barriers and resources for such policies and programmes; and future priorities and recommendations.Results Findings suggest perceptions among policy makers of barriers related to the mobile nature of tourism employees; the lack of centralized funding; fear of the 'image problem' associated with HIV; and the lack of multisectoral policy dialogue and collaboration. Nevertheless, prior short-term experiences and changing attitudes among some private sector tourism representatives suggest emerging opportunities for policy change.Conclusion We argue that the time is ripe for dialogue across the public-private divide in order to develop regulatory mechanisms, joint responsibilities and centralized funding sources to ensure a sustainable response to the HIV-tourism linkage. Policy priorities should focus on incorporating HIV prevention as a component of occupational health; reinforcing workers' health care rights as guaranteed by existing law; using private sector tourism representatives who support HIV prevention as positive role models for national campaigns; and disseminating a notion of 'investment' in safer tourism environments as a means to positively influence tourist demand. © The Author 2011; all rights reserved.

Marcano I.-E.,Autonomous University of Santo Domingo | Diaz-Alcantara C.-A.,Autonomous University of Santo Domingo | Urbano B.,University of Valladolid | Gonzalez-Andres F.,University of León
Soil Biology and Biochemistry | Year: 2016

Two hundred and sixty-one bacterial isolates associated with banana tree roots in organic systems were isolated from 19 farms located in four different provinces of the Dominican Republic. The isolates were analysed by means of ARDRA plus RAPD, and as a consequence 114 of them were selected for identification by means of complete 16S rRNA sequencing and phylogenetic reconstruction. The 114 isolates belonged to 20 different genera, with Bacillus, Pseudomonas, Enterobacter and Stenotrophomonas the prevailing genera. Of these, 65 isolates showed more than 99.5% similarity with a type strain, and they were assigned to 34 different species from 16 genera; 29 isolates could constitute new species and the remaining 20 isolates belonged to groups containing more than one species with identical 16S rRNA genes, and therefore they could not be assigned to any species. This result showed a higher number of bacterial taxa associated with banana tree roots than previously described. Additionally, we found seven bacterial species with significant in vitro plant growth promoting (PGP) activity, which had not been previously described as PGP bacteria in any crop. Field trials with isolates pre-selected based on their in vitro PGP activity showed that one strain of the species Pseudomonas plecoglossicida improved fruit yield and controlled the incidence of the disease black sigatoka caused by Mycosphaerella fijiensis. This activity was tentatively attributed to induced systemic resistance mechanisms. Bacterial diversity was analysed among the 261 isolates based on the Shannon index of diversity (H), calculated from the ARDRA profiles. Interestingly, the majority of the bacterial diversity was found within farms (86% of the total), being higher than the bacterial diversity between farms (14%). Moreover, the differences in the average H Index between provinces were very low. Consequently the biodiversity of the bacterial communities was little influenced by the soil characteristics. These results could work in favour of the efficient adaptation of the bacterial strains selected for use as plant probiotics in a range of soils in the region analysed. © 2016 Elsevier Ltd.

Puello A.,Autonomous University of Santo Domingo | Bhatti J.,Douglas Hospital Research Center | Salmi L.-R.,Institut Universitaire de France
Revista Panamericana de Salud Publica/Pan American Journal of Public Health | Year: 2013

Objective. To assess the feasibility of semiautomated linking of road traffic injury (RTI) cases in different data sets in low- and middle-income countries. Methods. The study population consisted of RTI cases in the Dominican Republic in 2010 and were identified in police and health insurance data sets. After duplicates were removed and fatality reporting was corrected by using forensic data, police and health insurance RTI records were linked if they had the same province, collision date, and gender of RTI cases and similar age within five years. A multinomial logistic regression model assessed the likelihood of being in only one of the data sets. Results. One of five records was a duplicate, including 21.1% of 6 396 police and 16.2% of 6 178 insurance records. Health insurance data recorded 43 of 417 deaths as only injured. Capture-recapture estimated that both data sets recorded one of five RTI cases. Characteristics associated with increased likelihood (P < 0.05) of being only in the police data set were female gender [adjusted odds ratio (OR) = 2.5], age ≥ 16 years (OR = 1.7), collision in the regions of Cibao Northeast (OR = 4.1) and Valdesia (OR = 6.4), day of occurrence from Tuesday to Saturday (ORs from 1.5 to 2.9), month of occurrence from October to December (ORs from 1.6 to 4.5), and occupant of four-wheeled vehicles (OR = 5.4) or trucks (OR = 5.3). Conclusions. Consistent semiautomated linking procedures were feasible to ascertain the RTI burden in the Dominican Republic and could be improved by standardized coding of police and health insurance RTI reporting.

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