Autonomous University of San Luis Potosi

www.uaslp.mx
San Luis Potosi, Mexico

The Autonomous University of San Luis Potosí is a public university in Mexico. It is the largest university in the state of San Luis Potosí. Among other historic milestones, in 1923 UASLP was the first university in Mexico to have autonomy constitutionally granted. Wikipedia.

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News Article | May 24, 2017
Site: www.marketwired.com

EDMONTON, ALBERTA--(Marketwired - May 24, 2017) - Altiplano Minerals Ltd. (TSX VENTURE:APN) ("APN" or the "Company") is pleased to announce the appointment of Osbaldo Zamora Vega as VP, Exploration. Mr. Zamora has a B.Sc. in Geology from the Autonomous University of San Luis Potosi, Mexico, an M.Sc. in Geochemistry from the National Autonomous University of Mexico, and is currently a Ph.D. candidate in Economic Geology at the University of Alberta. He is conducting research on ore-formation processes in the Zacatecas Mining District, Mexico, a world-class silver mining district. Mr. Zamora has 17 years of geological experience that ranges from precious metals exploration to mining, has worked for major companies such as PENOLES and Mauricio Hochschild as an exploration geologist, and participated actively in a drilling program that lead to the discovery of the Pinos Altos mine. He worked at La Cienega mine, a FRESNILLO PLC underground mine operation, performing underground mapping, grade control, planning and supervision of drilling programs, core logging, geological modeling, and reserve estimation. Additionally, he also has worked for junior companies including Continuum Resources Mexico in Oaxaca, Mexico, North Country Gold at the Three Bluffs project in Nunavut, Canada, and recently, for Altiplano Minerals Ltd on the generation of new projects. CEO John Williamson stated, "I am very pleased to have Osbaldo join the Altiplano team as I have worked with him since 2010 on various projects (including Brilliant Mining's projects in Africa) and can attest to his strength of character, work ethic and ability to add value to all projects that he collaborates on. Importantly, he is able to maintain a balance between the science of geology and business which is an important balance to achieve when evaluating and advancing projects." Altiplano Minerals Ltd. (TSX VENTURE:APN) is a mineral exploration company focused on evaluating and acquiring projects with significant potential for advancement from discovery through to production, in Canada and abroad. Management has a substantial record of success in capitalizing opportunity, overcoming challenges and building shareholder value. Additional information concerning Altiplano can be found on its website at www.altiplanominerals.com. ON BEHALF OF THE BOARD Neither the TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in the policies of the (TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release. This release includes certain statements that may be deemed "forward-looking statements". All statements in this release, other than statements of historical facts, that address exploration drilling, exploitation activities and events or developments that the Company expects are forward-looking statements. Although the Company believes the expectations expressed in such forward-looking statements are based on reasonable assumptions, such statements are not guarantees of future performance and actual results or developments may differ materially from those in the forward-looking statements. Factors that could cause actual results to differ materially from those in forward-looking statements include market prices, exploitation and exploration successes, continuity of mineralization, uncertainties related to the ability to obtain necessary permits, licenses and title and delays due to third party opposition, changes in government policies regarding mining and natural resource exploration and exploitation, and continued availability of capital and financing, and general economic, market or business conditions. Investors are cautioned that any such statements are not guarantees of future performance and actual results or developments may differ materially from those projected in the forward-looking statements. For more information on the Company, investors should review the Company's continuous disclosure filings that are available at www.sedar.com.


Arsenic (As) is a worldwide naturally occurring metalloid. Human chronic exposure to inorganic As compounds (iAs), which are at the top of hazardous substances (ATSDR, 2013), is associated with different diseases including cancer and non- cancerous diseases. The neurotoxic effects of iAs and its methylated metabolites have been demonstrated in exposed populations and experimental models. Impaired cognitive abilities have been described in children and adults chronically exposed to iAs through drinking water. Even though different association studies failed to demonstrate that As causes neurodegenerative diseases, several toxicity mechanisms of iAs parallel those mechanisms associated with neurodegeneration, including oxidative stress and inflammation, impaired protein degradation, autophagy, and intracellular accumulation, endoplasmic reticulum stress, and mitochondrial dysfunction. Additionally, different reports have shown that specifically in brain tissue, iAs and its metabolites induce hyper-phosphorylation of the tau protein and over-regulation of the amyloid precursor protein, impaired neurotransmitters synthesis and synaptic transmission, increased glutamate receptors activation, and decreased glutamate transporters expression. Interestingly, increased and sustained pro-inflammatory responses mediated by cytokines and related factors, seems to be the triggering factor for all of such cellular pathological effects. Therefore, this review proposes that iAs-associated cognitive impairment could be the result of the activation of pro-inflammatory responses in the brain tissue, which also may favor neurodegeneration or increase the risk for neurodegenerative diseases in exposed human populations. © 2016 Elsevier Inc.


Grant
Agency: European Commission | Branch: FP7 | Program: CP-FP | Phase: NMP.2010.1.2-4 | Award Amount: 3.75M | Year: 2010

Successful adaptation of nanotechnology in the end-products requires an access to the nanofiller technology and to the raw materials. The MINANO-project brings together partners representing end-users product know-how, formulation and processing technology and most importantly secure and reliable source of nano raw materials. Although there has been tremendous development in the area of nanocompounds with improved functionality, there exists a need to develop an efficient, continuous method of large-scale, low-cost synthesis of such materials. To answer to this need the following steps are suggested: 1) Integrate the functionalization of the high-quality nanoparticles directly on the continuous mass-production process already in the mining industry, 2) ensure controlled dispersion to the matrix material in large scale by cooperation between nanoparticle producer and end-product manufacturer, 3) assure sustainable and safe production and use by state-of-the-art life-cycle analysis. Based on the mass production process and cooperative value chain we concentrate on three major functionalities: Flame retardancy, UV resistance and antimicrobial properties. These properties are achieved by functionalized Mg(OH)2, ZnO and Ag nanoparticles. Societal and industrial impacts of these properties are extensive and there is a strong request of these functionalities for both plastic and wood-plastic based matrix materials. The use of nano-sized functional filler materials enables to use smaller amount of additives thus giving better recyclability, lower weight, higher mechanical strength and potential multifunctional features to the end-product. The combination of new nanofunctionalities gives far reaching possibilities for new types of functional plastics, and completely new possibilities to wood-plastic composites as well. This moves both mining industry and end-product companies towards high-tech on the long run.


Campos-Delgado D.U.,Autonomous University of San Luis Potosi | Espinoza-Trejo D.R.,Autonomous University of San Luis Potosi
IEEE Transactions on Industrial Electronics | Year: 2011

In this paper, the detection and isolation of open-switch faults in induction motor (IM) drives are addressed from a model-based perspective. Residuals are synthesized by using nonlinear observers followed from a directional characterization. First, it is observed that the IM model can be written in a recurrent decoupled structure by taking the stator currents and mechanical velocity as outputs. In this way, residuals can be insensitive to load torque and operating conditions, and simultaneous faults can be addressed. A pulsewidth modulation three-phase inverter is studied as power actuator for the IM. Hence, in order to isolate faults related to the six switching devices, a directional residual evaluation in the dq-frame is employed. Hence, three residuals are constructed to isolate the faulty switches. The ideas presented in this paper are validated experimentally in a test bench of 1-hp IM under single and simultaneous faults. © 2011 IEEE.


Fahraeus R.,University Paris Diderot | Olivares-Illana V.,Autonomous University of San Luis Potosi
Oncogene | Year: 2014

MDM2 is considered a hub protein due to its capacity to interact with a large number of different partners of which p53 is most well described. MDM2 is an E3 ubiquitin ligase, and many, but not all, of its interactions relate directly to this activity, such as substrates, adaptors or bridges, promoters, inhibitors or complementary factors. Some interactions serve regulatory functions that in response to cellular stresses control the localisation and functions of MDM2 including protein kinases, ribosomal proteins and proteases. Moreover, interactions with nucleotides serve other functions such as mRNA to regulate protein synthesis and DNA to control transcription. To perform such a pleiotropic panorama of different functions, MDM2 is subjected to a multitude of post-translational modifications and is expressed in different isoforms. The large and diverse interactome is made possible due to the plasticity of MDM2 and in this review we have listed the MDM2 interactions until now and we will discuss how this multifaceted protein can interact with such a variety of substrates to provide a key intermediary role in different signalling pathways.


Martinez-salinas R.I.,Autonomous University of San Luis Potosi
Environmental science and pollution research international | Year: 2011

The aim of this study was assess co-exposure to DDT, DDE (main DDT metabolite), and PAHs (1-hydroxypyrene) in areas where biomass is used to cook and to heat homes and where DDT was used to combat malaria transmission. During 2009, we analyzed a total of 190 blood and urine samples from children living in six communities in Mexico. Quantitative analyses of DDT and DDE were performed using gas chromatography coupled with mass spectrometry. Analyses of 1-hydroxypyrene were performed by HPLC using a fluorescence detector. In this work, we found high levels of DDT and its principal metabolite (DDE) in the blood of children living in four communities in Chiapas located in the southeastern region of Mexico (range,


Rosales-Mendoza S.,Autonomous University of San Luis Potosi
Expert review of vaccines | Year: 2013

Besides serving as a valuable model in biological sciences, Chamydomonas reinhardtii has been used during the last decade in the biotechnology arena to establish models for the low cost production of vaccines. Antigens from various pathogens including Plasmodium falciparum, foot and mouth disease virus, Staphylococcus aureus, classical swine fever virus (CSFV) as well as some auto-antigens, have been produced in C. reinhardtii. Although some of them have been functionally characterized with promising results, this review identifies future directions for the advancement in the exploitation of this robust and safe vaccine production platform. The present analysis reflects that important immunological implications exist for this system and remain unexplored, including the possible adjuvant effects of algae biomolecules, the effect of bioencapsulation on immunogenicity and the possible development of whole-cell vaccines as an approach to trigger cytotoxic immune responses. Recently described molecular strategies that aim to optimize the expression of nuclear-encoded target antigens are also discussed.


Quintana M.,Autonomous University of San Luis Potosi | Vazquez E.,University of Castilla - La Mancha | Prato M.,University of Trieste
Accounts of Chemical Research | Year: 2013

Graphene is considered a promising material for a range of new applications from flexible electronics to functional nanodevices, such as biosensors or intelligent coatings. Therefore researchers need to develop protocols for the mass production of graphene. One possible method is the exfoliation of graphite to form stable dispersions in organic solvents or even water. In addition, researchers need to find effective ways to control defects and locally induced chemical changes. We expect that traditional organic chemistry can provide solutions to many of these challenges. In this Account, we describe our efforts toward the production of stable dispersions of graphene in a variety of solvents at relatively high concentrations and summarize representative examples of the organic reactions that we have carried out using these stable dispersions.The sonication procedures used to solubilize graphene can often damage these materials. To mitigate these effects, we developed a new methodology that uses mechanochemical activation by ball-milling to exfoliate graphite through interactions with melamine (2,4,6-triamine-1,3,5-triazine) under solid conditions. Alternatively, the addition of reducing agents during sonication leads to larger graphene layers in DMF. Interestingly, the treatment with ferrocene aldehyde, used as a radical trap, induces the formation of multiwalled carbon nanotubes. The resulting graphene sheets, stabilized by the interactions with the solvent, are suitable materials for performing organic reactions.Relatively few organic reactions have been performed in stable dispersions of graphene, but organic functionalization of these materials offers the opportunity to tune their properties. In addition, thermal treatments can remove the appended organic moieties, restoring the intrinsic properties of pristine graphene. We describe a few examples of organic functionalization reactions of graphene, including 1,3-dipolar cycloadditions, amide condensations, nitrene additions, and radical reactions. The design of novel protocols for further organic functionalization should increase our knowledge of the fundamental chemistry of graphene and spur the further development and application of these materials. © 2012 American Chemical Society.


Rosales-Mendoza S.,Autonomous University of San Luis Potosi | Salazar-Gonzalez J.A.,Autonomous University of San Luis Potosi
Expert Review of Vaccines | Year: 2014

Genetically engineered plants can be used for the biomanufacture and delivery of oral vaccines. Although a myriad of antigens have been produced using this approach, improving our knowledge of their oral immunogenic properties is a priority as this aspect has not been well researched. Some studies have provided evidence of a higher immunogenic activity for antigens that were orally administered in the form of plant-based vaccines in comparison with conventional pure antigens. The characteristics of the plant-derived vaccines that may influence oral immunogenicity are identified and discussed in this review. Among the hypotheses explaining these immunogenic properties are the following: bioencapsulation favors antigen uptake and displays a resistance to degradation; plant metabolites exert adjuvant activity; plant compounds, such as polysaccharides, exert mucoadhesive properties; differential glycosylation conferred by the plant cell machinery enhances immunogenicity. Perspectives on how these hypotheses may be assessed are examined. © 2014 Informa UK, Ltd.


Melchor-Aguilar D.,Autonomous University of San Luis Potosi
Systems and Control Letters | Year: 2012

In this paper, we consider some classes of linear continuous time difference systems with discrete and distributed delays. For these infinite-dimensional systems, we derive new sufficient delay-dependent conditions for the exponential stability and exponential estimates for the solutions by using LyapunovKrasovskii functionals. © 2011 Elsevier B.V. All rights reserved.

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