The Benemérita Universidad Autónoma de Puebla is the oldest and largest university in Puebla, Mexico. Founded on 15 April 1587 as Colegio del Espíritu Santo, the school was sponsored by Society of Jesus during most of the Spanish colonial era before turning into a public college in 1825 and eventually into a public university in 1937. The religious origins can be seen in many of BUAP's buildings in Puebla city centre, which were once colonial-era churches. The flagship campus is located in the city of Puebla, although more than nine facilities are distributed across the state. Currently, it is one of the 105 institutes participating in the Alice Experiment at CERN. Wikipedia.
Flores G.,Autonomous University of Puebla |
Morales-Medina J.C.,Autonomous University of Tlaxcala |
Diaz A.,Autonomous University of Puebla
Behavioural Brain Research | Year: 2016
Schizophrenia, a severe and debilitating disorder with a high social burden, affects 1% of the adult world population. Available therapies are unable to treat all the symptoms, and result in strong side effects. For this reason, numerous animal models have been generated to elucidate the pathophysiology of this disorder. All these models present neuronal remodeling and abnormalities in spine stability. It is well known that the complexity in dendritic arborization determines the number of receptive synaptic contacts. Also the loss of dendritic spines and arbor stability are strongly associated with schizophrenia. This review evaluates changes in spine density and dendritic arborization in animal models of schizophrenia. By understanding these changes, pharmacological treatments can be designed to target specific neural systems to attenuate neuronal remodeling and associated behavioral deficits. © 2015 Elsevier B.V.
Garcia-Knight M.A.,Autonomous University of Puebla
AIDS | Year: 2017
OBJECTIVE:: Factors associated with poor health in HIV-exposed-uninfected (HEU) infants are poorly defined. We describe the prevalence and correlates of CMV viraemia in HEU and HIV-unexposed-uninfected (HUU) infants, and quantify associations with anthropometric, haematological and immunological outcomes. DESIGN:: Cross-sectional, including HEU and HUU infants from rural coastal Kenya. METHODS:: Infants aged 2–8 months were studied. The primary outcome was CMV viraemia and viral load, determined by quantitative PCR. Correlates were tested by logistic and linear regression; coefficients were used to describe associations between CMV viraemia and clinical/immunological parameters. RESULTS:: 42/65 (64.6%) infants had CMV viraemia (median viral load, 3.0 [IQR: 2.7–3.5] log10?IU/mL). Compared to community controls, HEU infants had 6-fold increased odds of being viraemic (adjusted OR 5.95 [95% CI: 1.82–19.36], P=0.003). Age, but not HEU/HUU status, was a strong correlate of CMV viral load (coeff?=?−0.15, P?=?0.009). CMV viral load associated negatively with weight-for-age z-score (coeff.?=?−1.06, P?=?0.008) and head circumference-for-age z-score (coeff.?=?−1.47, P?=?0.012) and positively with CD8 T cell co-expression of CD38/HLADR (coeff.?=?15.05, P?=?0.003). CONCLUSIONS:: The odds of having CMV viraemia was six-fold greater in HEU than HUU infants when adjusted for age. CMV viral load was associated with adverse growth and heightened CD8 T cell immune activation. Longitudinal assessments of the clinical effects of primary CMV infection and associated immunomodulation in early life in HEU and HUU populations are warranted. Copyright © 2017 Wolters Kluwer Health, Inc.
Flores G.,Autonomous University of Puebla |
Flores-Gomez G.D.,Universidad de Las Americas Puebla |
de Jesus Gomez-Villalobos M.,Autonomous University of Puebla
Synapse | Year: 2016
Vascular dementia is a devastating disorder not only for the patient, but also for the family because this neurocognitive disorder breaks the patient's independence, and leads to family care of the patient with a high cost for the family. This complex disorder alters memory, learning, judgment, emotional control and social behavior and affects 4% of the elderly world population. The high blood pressure or arterial hypertension is a major risk factor for cerebrovascular disease, which in most cases leads to vascular dementia. Interestingly, this neurocognitive disorder starts after long lasting hypertension, which is associated with reduced cerebral blood flow or hypoperfusion, and complete or incomplete ischemia with cortical thickness. Animal models have been generated to elucidate the pathophysiology of this disorder. It is known that dendritic complexity determines the receptive synaptic contacts, and the loss of dendritic spine and arbor stability are strongly associated with dementia in humans. This review evaluates relevant data of human and animal models that have investigated the link between long-lasting arterial hypertension and neural morphological changes in the context of vascular dementia. We examined the effect of chronic arterial hypertension and aged in vascular dementia. Neural dendritic morphology in the prefrontal cortex and the dorsal hippocampus and nucleus accumbens after chronic hypertension was diskussed in the animal models of hypertension. Chronic hypertension reduced the dendritic length and spine density in aged rats. © 2016 Wiley Periodicals, Inc.
Izrailev F.M.,Autonomous University of Puebla |
Krokhin A.A.,University of North Texas |
Makarov N.M.,Autonomous University of Puebla
Physics Reports | Year: 2012
This review presents a unified view on the problem of Anderson localization in one-dimensional weakly disordered systems with short-range and long-range statistical correlations in random potentials. The following models are analyzed: the models with continuous potentials, the tight-binding models of the Anderson type, and various Kronig-Penney models with different types of perturbations. Main attention is paid to the methods of obtaining the localization length in dependence on the controlling parameters of the models. Specific interest is in an emergence of effective mobility edges due to certain long-range correlations in a disorder. The predictions of the theoretical and numerical analysis are compared to recent experiments on microwave transmission through randomly filled waveguides. © 2011 Elsevier B.V..
Ostrovsky A.S.,Autonomous University of Puebla |
Rickenstorff-Parrao C.,Autonomous University of Puebla |
Arrizon V.,National Institute of Astrophysics, Optics and Electronics
Optics Letters | Year: 2013
We introduce the concept of the perfect optical vortex whose dark hollow radius does not depend on the topological charge. It is shown analytically and experimentally that such a vortex can be approximately generated in the Fourier transforming optical system with a computer-controlled liquid-crystal spatial light modulator. © 2013 Optical Society of America.
Escalante A.,Autonomous University of Puebla |
Zarate M.,Autonomous University of Puebla
Annals of Physics | Year: 2015
A detailed Hamiltonian analysis for a five-dimensional Stüeckelberg theory with a compact dimension is performed. First, we develop a pure Dirac's analysis of the theory; we show that after performing the compactification, the theory is reduced to four-dimensional Stüeckelberg theory plus a tower of Kaluza-Klein modes. We develop a complete analysis of the constraints, we fix the gauge and we show that there are present pseudo-Goldstone bosons. Then we quantize the theory by constructing the Dirac brackets. As complementary work, we perform the Faddeev-Jackiw quantization for the theory under study, and we calculate the generalized Faddeev-Jackiw brackets, we show that both the Faddeev-Jackiw and Dirac's brackets are the same. Finally we discuss some remarks and prospects. © 2014 Elsevier Inc.
Arganda E.,National University of La Plata |
Lorenzo Diaz-Cruz J.,Autonomous University of Puebla |
Szynkman A.,National University of La Plata
Physics Letters, Section B: Nuclear, Elementary Particle and High-Energy Physics | Year: 2013
The new SM-like Higgs boson discovered recently at the LHC, with mass mh≃125 GeV, as well as the direct LHC bounds on the mass of superpartners, which are entering into the TeV range, suggest that the minimal surviving supersymmetric extension of the SM (MSSM), should be characterized by a heavy SUSY-breaking scale. Several variants of the MSSM have been proposed to account for this result, which vary according to the accepted degree of fine-tuning. We propose an alternative scenario here, Slim SUSY, which contains sfermions with multi-TeV masses and gauginos/higgsinos near the EW scale, but it includes the heavy MSSM Higgs bosons (H0, A0, H±) near the EW scale too. We discuss first the formulation and constraints of the Slim SUSY scenario, and then identify distinctive heavy Higgs signals that could be searched at the LHC, within scenarios with the minimal number of superpartners with masses near the EW scale. © 2013 Elsevier B.V.
Autonomous University of Puebla | Date: 2013-07-26
A procedure of obtaining adsorbent from a waste material and its use are disclosed. This invention provides a natural waste material, specifically avocado seed, its preparation and use for the filling of columns used in the elimination of contaminants present in wastewater. The particles have an irregular shape and variable size for filling columns of different diameter and length. The adsorbent has sufficient hardness for avoiding a particle collapse. The material does not rot, is re-generable and ecological. In the present invention the preparation of the adsorbent, its pre-activation, carbonization and application to eliminate the color of textile wastewater is disclosed. The color elimination from textile wastewater, as well as decrease of salts, total suspended solids, chemical oxygen demand (COD) and total organic carbon (TOC), is carried out passing the textile wastewater through a column filled with the prepared adsorbent. In batch systems metals dissolved in water can be eliminated.
Autonomous University of Puebla | Date: 2012-09-14
A vestibular prosthesis includes micro-electric-mechanical (MEMS) sensors, gyroscopes in each sensitivity axis (X, Y, Z), accelerometers in each sensitivity axis (X, Y, Z) to detect an angular and linear movement providing displacement measurements, gyroscopes in each one of the spatial axes (X, Y, Z), a microprocessor connected to the MEMS sensors and producing an electric pulse pattern or a continuous galvanic current pattern, a conditioning unit that amplifies and conditions the microprocessor output to apply current to the stimulation electrodes, the microcontroller being configured to determine the displacement of the cupula and the otolithic mass, determine a membrane potential as a result of a displacement detected by the MEMS sensors by means of determining a transduction current, and determine an action potential discharge pattern for the primary afferent neuron, which synapses with the hair cell by means of a mathematical model of the informative process of the vestibular mechanoreceptor.
Autonomous University of Puebla | Date: 2012-09-14
A stabilometric system is provided that uses a balance platform to detect problems in the vestibular system via data capture, data visualization and mathematical analysis of data, the system having means for data capture that obtain customized records and store data resulting from the readings of the sensors of the balance platform, means for displaying the data obtained using stabilometric tests on a screen that is controlled by a computer, and means for processing the data obtained from the measurements.