Aurobindo Pharma Pvt Ltd

Medak, India

Aurobindo Pharma Pvt Ltd

Medak, India
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PubMed | Aurobindo Pharma Pvt Ltd and Acharya Nagarjuna University
Type: Journal Article | Journal: Scientia pharmaceutica | Year: 2016

Drug product purity and potency are of most significance in the regulatory market as we notice many recalled batches worldwide, particularly in the US and Japan. Olmesartan Medoxomil is an anti-hypertensive drug. The present invention relates to a process for the preparation of Olmesartan Medoxomil with 99.9% purity in an overall 62% yield. The synthesis includes three isolations and one purification with easy plant operations. This process describes the formation and control of each individual impurity in all stages. This process for Olmesartan Medoxomil and its intermediates is competent for industrial production in very short reaction time intervals with an appreciable yield and high purity.

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