Zavaleta Gutierrez N.,National Atomic Energy Commission |
De Cicco H.,National Atomic Energy Commission |
Danon C.A.,National Atomic Energy Commission |
Luppo M.I.,National Atomic Energy Commission
Materials Science and Engineering A | Year: 2011
Ferritic-martensitic steels of the 9%Cr1%Mo type have been extensively used in power plant components, heat exchangers, piping and tubing, etc., due to an excellent combination of properties such as creep resistance, toughness and resistance to oxidation at high temperatures. In these steels the stabilizing role of MX carbonitrides (M = Nb, V; X = C, N) is one of the main factors responsible for the resistance under creep conditions. The control of precipitation and coarsening of MX phases during prolonged, high temperature tempering or post-weld heat treatment is then a key point to obtain the desirable microstructure and hence, to achieve high temperature resistance under service conditions.In the present contribution we report the evolution of the precipitated phases during heat treatment at 780°C for increasing times in the range 40. min to 7. h for an ASTM A213 T91 steel. The Nb and V contents in solid solution were determined as a function of the time of treatment and maxima were observed for 5 and 5.66. h, respectively. Creep tests to rupture were also conducted at 600°C - 190. MPa for as-treated specimens. A maximum creep rate was observed to occur in coincidence with the maximum values of Nb and V contents in solid solution. We suggest possible relationships between the observed second phase evolution and the creep resistance behavior. © 2011 Elsevier B.V.
PubMed | National Atomic Energy Commission, Santa Lucia Ophthalmology Hospital, Otamendi Hospital and Nuclear Regulatory Authority
Type: | Journal: Radiation protection dosimetry | Year: 2016
High levels of scatter radiation in catheterization laboratories may lead to posterior subcapsular opacities in the lens of the staff. The international Retrospective Evaluation of Lens Injuries and Dose (RELID) was performed in Argentina for the first time in 2010 in the context of the congress of the Latin American Society of Interventional Cardiology (SOLACI) and recently, in 2014, was carried out for the second time (SOLACI-CACI 2014). The 2014 study included 115 participants: interventional cardiologists, technicians and nurses. Posterior subcapsular lens changes typical of ionizing radiation exposure were found in 91.5% of interventional cardiologists, in 77% of technicians and in 100% of nurses, according to the Merriam-Focht scale. This RELID study (Argentina 2014) has particular importance since it allowed the follow-up of 10 professionals evaluated in 2010. The results obtained in the study population highlight the importance of the availability and proper use of the elements of radiation protection, as well as staff training.
Braslavsky S.E.,Max Planck Institute for Chemistry |
Braun A.M.,Karlsruhe Institute of Technology |
Cassano A.E.,National University of Santa |
Emeline A.V.,Saint Petersburg State University |
And 4 more authors.
Pure and Applied Chemistry | Year: 2011
This glossary of terms covers phenomena considered under the very wide terms photocatalysis and radiation catalysis. A clear distinction is made between phenomena related to either photochemistry and photocatalysis or radiation chemistry and radiation catalysis. The term "radiation" is used here as embracing electromagnetic radiation of all wavelengths, but in general excluding fast-moving particles. Consistent definitions are given of terms in the areas mentioned above, as well as definitions of the most important parameters used for the quantitative description of the phenomena. Terms related to the up-scaling of photocatalytic processes for industrial applications have been included. This Glossary should be used together with the Glossary of terms used in photochemistry, 3rd edition, IUPAC Recommendations 2006: (doi:10.1351/pac200779030293) as well as with the IUPAC Compendium of Chemical Terminology, 2nd ed. (the "Gold Book" 2006-; doi:10.1351/goldbook), because many terms used in photocatalysis are defined in these documents. © 2011 IUPAC.
Lester G.E.,U.S. Department of Agriculture |
Hallman G.J.,U.S. Department of Agriculture |
Perez J.A.,National Atomic Energy Commission
Journal of Agricultural and Food Chemistry | Year: 2010
Ionizing radiation of fruits and vegetables, in the form of γ rays or electron beams, is effective in overcoming quarantine barriers in trade and prolonging shelf life, but a void of information persists on ionizing radiation effects of vitamin profiles in individual foods. Baby-leaf spinach from commercial cultivars, flat-leafed 'Lazio' and crinkled-leaf 'Samish', was grown, harvested, and surface sanitized according to industry practices. Baby-leaf spinach of each cultivar was packaged under air or N2 atmosphere, representing industry practices, then exposed to cesium-137 γ-radiation at 0.0, 0.5, 1.0, 1.5, or 2.0 kGy. Following irradiation, leaf tissues were assayed for vitamin (C, E, K, B9) and carotenoid (lutein/zeaxanthin, neoxanthin, violoxanthin, and β-carotene) concentrations. Atmospheres by irradiation had little consistent effect, but N2 versus air was associated with elevated dihydroascorbic acid levels. Four phytonutrients (vitamins B9, E, and K and neoxanthin) exhibited little or no change in concentration with increasing doses of irradiation. However, total ascorbic acid (vitamin C), free ascorbic acid, lutein/zeaxanthin, violaxanthin, and β-carotene all were significantly reduced at 2.0 kGy and, depending on cultivar, were affected at lesser doses of 0.5 and 1.5 kGy. Dihydroascorbic acid, the most affected compound and an indicator of stress, likely due to irradiation-generated oxidative radicals, increased with increasing irradiation doses >0.5 kGy. © 2010 American Chemical Society.
Tomac A.,University of the Sea |
Tomac A.,CONICET |
Cova M.C.,National Atomic Energy Commission |
Narvaiz P.,National Atomic Energy Commission |
And 2 more authors.
Radiation Physics and Chemistry | Year: 2015
The effect of gamma irradiation (0, 2, 3 and 4. kGy) on vacuum-packed marinated anchovy fillets was analyzed for their texture, color, lipid oxidation and sensory acceptability after 10 months under refrigeration. Marinated (3% acetic acid, 10% sodium chloride and 0.2% citric acid) Engraulis anchoita fillets were vacuum-packed and irradiated with a cobalt-60 source at a semi-industrial irradiation facility. The irradiation caused a slight increase in hardness values regardless of the applied dose but maintained a consistent texture over the 10 months, even though the control samples softened, most likely due to degradation. This hardness increase did not affect the textural sensory acceptability. Irradiation did not modify the color but still reduced color changes during storage, benefitting the product's quality. TBARS was increased in every sample throughout storage, but irradiation decreased these values. Sensory acceptability was not affected by gamma irradiation. Therefore, gamma irradiation could be successfully applied to this type of product for the purpose of shelf-life extension. © 2014 Elsevier Ltd.
Barbaglia M.O.,CONICET |
Bruzzone H.,CONICET |
Acuna H.N.,CONICET |
Soto L.,Center for Research and Applications in Plasma Physics |
And 2 more authors.
IEEE Transactions on Plasma Science | Year: 2014
Measurements of electrical signals in discharges performed in a miniature plasma-focus device (5 nF capacitor bank, central electrode diameter and effective free length 2.0 and 0.5 mm, respectively, no outer electrode) are reported. A lumped model is built that gives good agreement between the model and the recorded signals. The main conclusions are as follows: the voltage at which the chamber disk capacitor is charged is limited by the gas filling pressure inside the chamber and not just by the voltage in the capacitor energy source, and the behavior of the discharge current within the vacuum chamber depends on the whole system and not only on the last portion of the circuit, even for longer transmission line lengths. © 1973-2012 IEEE.
PubMed | CONICET, National Atomic Energy Commission, University of Buenos Aires and Idaho National Laboratory
Type: Journal Article | Journal: Oral diseases | Year: 2015
Searching for more effective and selective therapies for head and neck cancer, we demonstrated the therapeutic effect of boron neutron capture therapy (BNCT) to treat oral cancer and inhibit long-term tumor development from field-cancerized tissue in the hamster cheek pouch model. However, BNCT-induced mucositis in field-cancerized tissue was dose limiting. In a clinical scenario, oral mucositis affects patients treatment and quality of life. Our aim was to evaluate different radioprotectors, seeking to reduce the incidence of BNCT-induced severe mucositis in field-cancerized tissue.Cancerized pouches treated with BNCT mediated by boronophenylalanine at 5 Gy were treated as follows: control: saline solution; Hishigh : histamine 5 mg kg(-1) ; Hislow : histamine 1 mg kg(-1) ; and JNJ7777120: 10 mg kg(-1).Hislow reduced the incidence of severe mucositis in field-cancerized tissue to 17% vs55%; Hishigh : 67%; JNJ7777120: 57%. Hislow was non-toxic and did not compromise the long-term therapeutic effect of BNCT or alter gross boron concentration.Histamine reduces BNCT-induced mucositis in experimental oral precancer without jeopardizing therapeutic efficacy. The fact that both histamine and boronophenylalanine are approved for use in humans bridges the gap between experimental work and potential clinical application to reduce BNCT-induced radiotoxicity in patients with head and neck cancer.
Pirchio R.,National Atomic Energy Commission |
Sanchez H.,National Atomic Energy Commission |
Domazet W.,Sanatorium Dr Julio Mendez
Radiation Measurements | Year: 2014
During interventional radiology (IR) and cardiology (IC) procedures, medical staff can receive high doses to their eye lenses. The Retrospective Evaluation of Lens Injuries and Dose study organized in Argentina in 2010 found incipient opacity in 50% of IC physicians and 41% of IC technicians/nurses. These results, added to the recommendations of the International Commission on Radiological Protection, which lowered their former occupational equivalent dose limit for the lens, led us to assess the eye lens dose, Hp(3), during interventional procedures. To this end, a new dosemeter was designed and calibrated at the National Atomic Energy Commission of Argentina to evaluate Hp(3). Personal dose equivalent (Hp(10)), and Hp(3) were assessed for 3 months in two IC and IR departments. An Alderson phantom was used to simulate monthly exposures of five occupational staff members. Hp(3) and Hp(10) were obtained monthly for 14 occupational staff members exposed to 121 IR and IC procedures. We concluded that the annual effective dose and Hp(3) were lower than 0.3 and 10 mSv, respectively and the average cumulative Hp(3) for working life was lower than 400 and 200 mSv for physicians and technicians/scrub nurse, respectively. An occupational annual dose constraint of 0.3 mSv was calculated. © 2014 Elsevier Ltd. All rights reserved.
Olmedo D.G.,University of Buenos Aires |
Paparella M.L.,University of Buenos Aires |
Brandizzi D.,National Atomic Energy Commission |
Cabrini R.L.,University of Buenos Aires
International Journal of Oral and Maxillofacial Surgery | Year: 2010
The aim of this study was to report 2 novel clinical cases of reactive lesions of the peri-implant mucosa associated with titanium dental implants where metal-like particles were observed histologically. In both cases, the lesions were diagnosed as epulis, based on clinical evidence. Extirpation biopsies were carried out. Case 1 was diagnosed as pyogenic granuloma and case 2 as peripheral giant cell granuloma. The presence of metal-like particles in the tissues suggests that the etiology of the lesions might be related to the corrosion process of the metal structure. This is the first case of pyogenic granuloma to be reported in association with dental implants. All clinical cases of soft tissue lesions associated with implants should be reported to contribute to the understanding of the etiology and pathogeny of these lesions. © 2009 International Association of Oral and Maxillofacial Surgeons.
PubMed | National Atomic Energy Commission and University of Buenos Aires
Type: Journal Article | Journal: International journal of radiation oncology, biology, physics | Year: 2015
Patients with the same histopathologic diagnosis of cutaneous melanoma treated with identical protocols of boron neutron capture therapy (BNCT) have shown different clinical outcomes. The objective of the present studies was to evaluate the biodistribution of boronophenilalanina ((10)BPA) for the potential application of BNCT for the treatment of melanoma on an individual basis.The boronophenilalanine (BPA) uptake was evaluated in 3 human melanoma cell lines: MEL-J, A375, and M8. NIH nude mice were implanted with 4 10(6) MEL-J cells, and biodistribution studies of BPA (350 mg/kg intraperitoneally) were performed. Static infrared imaging using a specially modified infrared camera adapted to measure the body infrared radiance of small animals was used. Proliferation marker, Ki-67, and endothelial marker, CD31, were analyzed in tumor samples.The in vitro studies demonstrated different patterns of BPA uptake for each analyzed cell line (P<.001 for MEL-J and A375 vs M8 cells). The in vivo studies showed a maximum average boron concentration of 25.9 2.6 g/g in tumor, with individual values ranging between 11.7 and 52.0 g/g of (10)B 2 hours after the injection of BPA. Tumor temperature always decreased as the tumors increased in size, with values ranging between 37 C and 23 C. A significant correlation between tumor temperature and tumor-to-blood boron concentration ratio was found (R(2) = 0.7, rational function fit). The immunohistochemical studies revealed, in tumors with extensive areas of viability, a high number of positive cells for Ki-67, blood vessels of large diameter evidenced by the marker CD31, and a direct logistic correlation between proliferative status and boron concentration difference between tumor and blood (R(2) = 0.81, logistic function fit).We propose that these methods could be suitable for designing new screening protocols applied before melanoma BNCT treatment for each individual patient and lesion.