Atma Jaya Catholic University of Indonesia
Jakarta, Indonesia

Atma Jaya Catholic University of Indonesia is an institute of higher learning in Jakarta, Indonesia, which was founded by Atma Jaya Foundation on June 1, 1960. The main campus is located at Semanggi area, South Jakarta and the other campus is located in Pluit, North Jakarta.According to a survey by GlobeAsia Magazine in 2008 Atma Jaya was ranked third among all private universities in Indonesia. While the survey of Tempo magazine from 2005 to 2007 put Atma Jaya in the top ten best universities in Indonesia. The General Directorate of Higher Education categorizes Atma Jaya in 50 Promising Indonesian Universities out of 2864 higher education institutions in Indonesia.Since 2008 Atma Jaya has been increasing the number of undergraduate and graduate programs, and is constructing a new campus in Bumi Serpong Damai, Tangerang. Wikipedia.

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Setyanto D.,Atma Jaya Catholic University of Indonesia
Procedia Engineering | Year: 2017

The height crest profile of metal roofing sheets is the common option for Japanese factory buildings in Indonesia. The metal roofing sheets are installed on the supporting bars/ purlins with mechanical locking system without any holes. Based on this system, the paper describes how to design a similar height crest profile of roofing sheets made of a GFRP composite material that is produced in a continuous laminating machine. It was found six types of height crest profiles that are met to the profile that is installed on the purlins by mechanical locking system. The six roofing sheets structures are simulated with uniform static forces on the two local areas of valley of roofing sheets by using finite element method. Based on both stress and deflection distribution of the six finite element models of roofing sheet structure, the selected type of crest profile is the trapezoidal. The roofing sheets of GFRP material consist of three trapezoidal type crests and two valleys. It was produced in a continuous laminating machine by using seven until twenty rows of mold. A row/ set of mold consist of three parts, one bottom part and two upper parts. © 2017 The Authors.

Cole P.,University of Delaware | Hermon G.,University of Delaware | Yanti,Atma Jaya Catholic University of Indonesia
Cognition | Year: 2015

Languages around the world often appear to manifest nearly identical grammatical properties, but, at the same time, the grammatical differences can also be great, sometimes even seeming to support Joos's (1958) claim that "languages can differ from each other without limit and in unpredictable way" (p. 96). This state of affairs provides a puzzle for both nativist approaches to language like Generative Grammar that posit a fixed "Universal Grammar", and for approaches that minimize the contribution of innate grammatical structure. We approach this puzzling state of affairs by looking at one area of grammar, "Binding", the system of local and long distance anaphoric elements in a language. This is an area of grammar that has long been central to the Generative approach to language structure. We compare the anaphoric systems found in "familiar" (European-like) languages that contain dedicated classes of bound and free anaphors (pronouns and reflexives) with the anaphoric systems in endangered Austronesian languages of Indonesia, languages in which there is overlap or no distinction between pronouns and reflexives (Peranakan Javanese and Jambi Malay). What is of special interest about Jambi anaphora is not only that conservative dialects of Jambi Malay do not distinguish between pronouns and reflexives, but that Jambi anaphora appear to constitute a live snapshot of a unitary class of anaphora in the process of grammaticalization as a distinct system of pronouns and reflexives.We argue that the facts of Jambi anaphora cannot be explained by theories positing a Universal Grammar of Binding. Thus, these facts provide evidence that complex grammatical systems like Binding cannot be innate. Our results from Austronesian languages are confirmed by data from signed and creole languages. Our conclusion is that the human language learning capacity must include the ability to model the full complexity found in the syntax of the world's languages. From the perspective of child language acquisition, these conclusions suggest that Universal Grammar does not provide a general solution to the problem of poverty of the stimulus, and the solution to that problem must reside at least in part in special properties of the grammar construction tools available to the language learner rather than simply in a fixed set of grammatical rules hard wired into the brains of speakers. © 2015 Elsevier B.V.

Setyanto D.,Atma Jaya Catholic University of Indonesia
AIP Conference Proceedings | Year: 2016

The 1.25mm thickness of opaque glass fiber reinforced polymer (GFRP) composite sheet roof that is produced by an Indonesia company at Tangerang, consists of two layers of 300g/m2 E-glass chopped strand mat as reinforcement and unsaturated polyester resin as matrix. A layer of 300g/m2 E-glass chopped strand mat is replaced by a layer of 400g/m2 E-glass woven roving as reinforcement to study the possibility use as sheet roof material. The properties of the two samples of GFRP composite materials were compared. Barcol hardness and flexure strength of the two samples relatively not significance change. Tensile strength and elastic modulus of the new sample which contains a layer of woven roving reinforcement is greater than the other one. On the other hand the waviness of the new sample is greater, but cheaper. In general, a layer of E-glass woven roving and a layer of E-glass chopped strand mat can be considered as an alternative reinforcement of two layers reinforcement of GFRP composite material of sheet roof. © 2016 AIP Publishing LLC.

Prasasty V.D.,Atma Jaya Catholic University of Indonesia | Yulandi A.,Atma Jaya Catholic University of Indonesia
International Journal of Pharmacy and Pharmaceutical Sciences | Year: 2015

Objectives: The aim of this research is to investigate the better biological activities from Rilpivirine analogues based on their Quantitative Structure-Property Relationship (QSPR) and pharmacophore study. Methods: In this study, we had designed six Rilpivirine analogues. The complementary aided-computational drug design and molecular docking was employed to find the best lead candidate. The drug-likeness properties of Rilpivirine analogues were defined by following the Rule of Five. Results: The drug-likeness properties of Rilpivirine derivatives (RVN 1-6) were defined by the Rule of Five (RO5), which RVN3 compound showed the best RO5 score among others. However, the log P value of RVN1 and RVN4 are lower than 5, while RVN2, RVN3, RVN5 and RVN6 have log P values greater than 5. Based on the solubility, RVN1 and RVN4 compounds are more soluble than other analogues including Rilpivirine prototype (RVN). The topological polar surface area (TPSA) score of RVN1 and RVN4 showed greater scores compared to others. On the other hand, the TPSA score of all Rilpivirine analogues are below 140 Å2. The absorption, distribution, metabolism, and excretion (ADME) properties of Rilpivirine analogues were determined, according to blood brain barrier penetration were found within the range of-1.2 to-2.2, which RVN4 showed the lowest value compared to others, while RVN showed the highest value. The percentage of human intestinal absorption was observed 100% to all compounds. The plasma protein binding percentages was obtained within the range 99.03-99.57%. Moreover, the hydrogen bond donor contribution of all compounds was in the range 2-4 bonds, while the acceptor hydrogen bond was found 6 bonds from all compounds. The mutagenicity properties showed all compounds could cause mutagenic effect in long-term administration. The carcinogenicity tests were done in mouse showed positive results to all compounds, while carcinogenicity test in rat showed negative results upon all compound, except RVN3 which gave positive result. From molecular docking result, RVN 1 and RVN 4 showed higher potential inhibition activities to Reverse Transcriptase Human Immunodeficiency Virus Type 1 (HIV-1 RT) compared other analogues. Conclusion: Non-nucleoside reverse transcriptase inhibitors (NNRTIs) have a great potential inhibition against HIV-1 RT. From high throughput computational approach, we suggested that RVN 1 and RVN 4 are the potential drug candidates which have better activity among other Rilpivirine derivatives. © 2014 All Rights Reserved.

Setyanto D.,Atma Jaya Catholic University of Indonesia
Procedia Engineering | Year: 2014

The characteristics of sheet molding compound (SMC) roof tiles are: lightness, high strength, high stiffness, and corrosion resistance. This paper describes a trial production of SMC roof tiles in a composite manufacturing industry in Tangerang, Indonesia. The SMC roof tiles samples were then characterized and evaluated to determine the mechanical properties of the material and the performance of the roof structure. Mechanical properties of the material, i.e. the tensile strength and the elastic modulus, were obtained from the tensile test. Evaluation of the SMC roof tiles as a roof structure was carried out by static loads testing of the roof structure model. The tensile test according to ASTM D638: 2003 shows that the tensile strength and the elastic modulus of the SMC material are 30 ± 3 MPa and 10 ± 1 GPa, respectively. Failure of the SMC roof tiles as a roof structure when loaded by static load of cylindrical steel loads due to crack occurred at 94 kgs load. © 2014 The Authors. Published by Elsevier Ltd.

Sari L.,Atma Jaya Catholic University of Indonesia
Telkomnika | Year: 2012

Punctured convolutional codes are known to have low complexity compared to their nonpunctured counterpart, while retaining a good performance. Analyzing the performance of punctured convolutional code can be simplified by using non-punctured equivalent code. In this paper new punctured convolutional codes with rates of 3/8, 3/7 and 3/6 are proposed, and their performances are studied by first constructing non-punctured equivalent codes. Simulations results show that different puncturing patterns will affect the code performances. Further investigations show that puncturing adjacent bits is to be avoided as it tends to degrade the code performance, as indicated by a decrease of the free distance by 9% and 33% below average for code rates 3/7 and 3/6 respectively. On the contrary, dispersed punctured bits will yield good code performance as indicated in the increase of the free distance by 27% and 32.45% above average for code rates 3/7 and 3/6 respectively.

Handajani Y.S.,Atma Jaya Catholic University of Indonesia
Acta medica Indonesiana | Year: 2012

to provide an overview of the quality of life (OQL) for people living with HIV/AIDS (PLWHA) in Jakarta, particularly in the Kramat 128 Hospital, based on CD4 and viral load (VL) levels and the length of antiretroviral (ARV) treatment. a cross-sectional study performed at Kramat 128 Hospital Jakarta Outpatient Clinic from November 2010 to January 2011. Quality of life was assessed with the WHOQOL-BREF instrument. The data were analyzed using Chi-Square test, independent T-test, and One-Way Analysis of Variance (ANOVA) test. the mean score in four domains of QOL in descending order were psychological (72.27), physical health (70.10), environment (65.59), and social relationships (64.44). There were a significant differences in overall QOL (p=0.000) and general health (p=0.001) between lower and higher CD4 levels. Patients who were interviewed look healthy physically and psychologically, have a good QOL based on statistical analysis. Patients with undetectable VL levels had better in general health (p=0.012), and those with longer ARV therapy (>1 year) had better overall QOL (p=0.024) and general health (p=0.003). Analysis with four domains of QOL showed a significant relationship of CD4 levels with the physical health (p=0.001) and psychological domain (p=0.043). VL levels showed significant relationships with the four domains of QOL (p<0.05). Duration of ARV therapy showed a significant association only with physical health domain (p=0.015). higher CD4 levels, undetectable VL, and longer ARV therapy will increase patient's QOL. Higher QOL will make the patient have ability to cope with illness. So, a better QOL can be taken as indicator of successful ARV treatment.

In periodontal disease, gingival fibroblasts activated by the Gram-negative anaerobic bacterium Porphyromonas gingivalis induce overexpression of matrix metalloproteinase-2 (MMP-2), which is involved in inflammatory progression. This process is followed by tissue destruction and bone loss. In the present study, we investigated the in vitro effect of the ethanolic Kaempferia pandurata Roxb. extract on expression of MMP-2 in P. gingivalis-treated human gingival fibroblast-1 (HGF-1) cells. In addition, we utilized gelatin zymography, Western blotting, and reverse transcription-PCR analysis to elucidate the molecular mechanisms underlying MMP-2 inhibition via the mitogen-activated protein kinase (MAPK) and cyclic AMP response element-binding protein (CREB) signaling pathways. Treatment with K. pandurata extract (1-10 μg/ml) dose-dependently suppressed the activity, secretion, and protein expression of MMP-2 in HGF-1 cells exposed to P. gingivalis. At the transcriptional level, inhibition of MMP-2 gene expression by K. pandurata was mediated by phosphorylation of c-Jun N-terminal kinase (JNK) and CREB signaling pathways in P. gingivalis-treated HGF-1 cells. These results suggest that K. pandurata extract suppresses MMP-2 expression at the protein and gene levels via downregulation of the principal JNK and CREB signaling pathways. Due to its efficacy in inhibiting MMP-mediated periodontal destruction, K. pandurata might represent a new, potent periodontal therapy.

Pramudita A.A.,Atma Jaya Catholic University of Indonesia
Proceedings of the 2015 IEEE 5th Asia-Pacific Conference on Synthetic Aperture Radar, APSAR 2015 | Year: 2015

An Antenna with stable footprint is crucial for GPR system to perform. In regards to the problem of varying soil condition, the design of UWB reconfigurable antenna with footprint adjustment capability was studied as an antenna system for GPR. The antenna system consists of several U-shape micro strip UWB antennas with resistive loading. Reconfiguration of the propose antenna is performed by controlling the switching device which is used to connect each U-shape micro strip UWB antenna. The reconfiguration scheme gives possibility to adjust the antenna footprint by manipulated the effective aperture of the antenna. Larger footprint is generated by increasing the number of U-shape micro strip UWB that are connected to each other and vise versa for smaller footprint. The theoretical analysis has been done to investigate the reconfigurable antenna concept for footprint adjustment and the result shows that the reconfigurable antenna concept is capable to adjust the footprint size of the antenna. © 2015 IEEE.

Yanti,Atma Jaya Catholic University of Indonesia
American Journal of Biochemistry and Biotechnology | Year: 2011

Problem statement: Atherosclerosis is associated with chronic inflammation triggered by bacterial infection that activates the breakdown of extracellular matrix protein by matrix Metalloproteinases (MMPs). Zingiberaceae, a group of tropical food crops grown in Indonesia and other Southeast Asia regions, has been traditionally used for food coloring, seasoning, culinary and medicinal purposes. However, its efficacy as natural vascular protection has not been explored. Approach: The research was aimed to investigate the effects of 10 Indonesian Zingiberaceae rhizome extracts on inhibition of MMP-9 expression in human vascular endothelial cells treated with Lipopolysaccharide (LPS) in vitro by conducting gelatin zymogram, Western blotting and RT-PCR assays. Results: LPS (2 μg mL -1) significantly elevated the expression of MMP-9 secretion, protein and mRNA in the vascular endothelial cells. Selected Zingiberaceae exctracts (5 μg mL -1), i.e., Curcuma xanthorrhiza, C. aeruginosa, C. mangga, C. longa, Kaempferia galanga, Alpinia galangal and Zingiberaceae officinale, effectively attenuated the expression of MMP-9 secretion, protein and mRNA in LPS-induced vascular endothelial cells. Furthermore, MMP-9 expression was specifically blocked by MAPK inhibitors, i.e., PD98059 (ERK1/2 inhibitor), SB203580 (p38 inhibitor), SP600125 (JNK inhibitor) and PI3K inhibitor (LY294002), indicating that MAPK and PI3K signaling pathways are involved in regulation of MMP-9 gene expression in LPS-induced vascular endothelial cells. Conclusion: These results suggest that selected Indonesian Zingiberaceae rhizomes with potent MMP-9 inhibitory activity may scientifically offer the promising therapeutic target in vascular diseases, particularly atherosclerosis. © 2010 Science Publications.

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