Bet Shemesh, Israel
Bet Shemesh, Israel

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Grant
Agency: European Commission | Branch: FP7 | Program: CP-FP | Phase: KBBE.2010.1.2-08 | Award Amount: 4.56M | Year: 2011

The two core objectives of BIVALIFE are (i) to provide innovative knowledge related to pathogens infecting oysters and mussels and (ii) to develop practical approaches for the control of infectious diseases and resulting mortality outbreaks these pathogens induce. The project will address the major issue identified by the European commission (i.e. detection and management of infectious diseases in oysters and mussels) at the EU level since the increase in international and intra EU trade and exchanges of animals increases the risk of pathogen transfer and infectious disease outbreak occurrence. In this context, the specific objective of BIVALIFE are: (i) transfer and validate existing methods for detection and identification of oyster and mussel pathogens; (ii) improve the characterisation of oyster and mussel pathogens and develop innovative complementary diagnostic approaches; (iii) characterise culture sites in Europe regarding presence of oyster and mussel pathogens in relation to the presence or absence of mortality; (iv) investigate the life cycle, mechanisms allowing oyster and mussel pathogens to survive outside the host and their original source; (v) identify pathogen intrinsic virulence factors and effects on host defence mechanisms; (vi) assess the relationship between the presence of oyster and mussel pathogens and their role in observed mortality; (vii) develop methods and recommendations for pathogen control and eradication in Europe. The project will focus on three mollusc species, namely the Pacific cupped oyster Crassostrea gigas and two mussel species Mytilus edulis and M. galloprovincialis, the most important species in terms of European production. Interestingly, Pacific oysters and mussels display different levels of susceptibility to diseases. The targeted pathogens will be the virus OsHV-1, Vibrio species including V. splendidus and V. aestuarianus, as well as the parasite Marteilia refringens and the bacterium Nocardia crassostreae.


Grant
Agency: European Commission | Branch: H2020 | Program: RIA | Phase: SFS-10b-2015 | Award Amount: 5.41M | Year: 2016

The overarching goal of VIVALDI is to increase the sustainability and competitiveness of the European shellfish industry by improving the understanding of bivalve diseases and by developing innovative solutions and tools for the prevention, control and mitigation of the major pathogens affecting the main European farmed shellfish species: Pacific oyster (Crassostrea gigas), mussels (Mytilus edulis and M. galloprovincialis), European flat oyster (Ostrea edulis), clams (Venerupis philipinarum) and scallops (Pecten maximus ). The project addresses the most harmful pathogens affecting either one or more of these shellfish species: the virus OsHV-1, Vibrio species including V. aestuarianus, V. splendidus, V. harveyi and V. tapetis, as well as the parasite Bonamia ostreae. The project is committed to provide practical solutions based on the most advanced knowledge. VIVALDI will dissect the disease mechanisms associated with pathogen virulence and pathogenesis and host immune responses, develop in vivo and in vitro models, and apply omic approaches that will help the development of diagnostic tools and drugs against pathogen targets, and breeding programmes in a collaborative effort with industrial partners. The proposal will include a global shellfish health approach, recognising that cultured bivalves are often exposed to several pathogens simultaneously, and that disease outbreaks can be due to the combined effect of two or more pathogens. The proposal will also investigate advantages and risks of the used of disease-resistant selected animals in order to improve consumer confidence and safety. VIVALDI will be both multi- and trans-disciplinary. In order to cover both basic and applied levels from molecules to farm, the proposal will integrate partners with a broad range of complementary expertises in pathology and animal health, epidemiology, immunology, molecular biology, genetics, genomics and food safety.


A method and a system is provided for inactivation of Infectious Pancreatic Necrosis Virus (IPNV) comprising illuminating a liquid containing IPNV with a lamp emitting a continuous broad band of ultraviolet (UV) light. The UV lamp may be tuned to optimize IPNV inactivation. The lamp may be a medium pressure UV lamp that emits UV light having wavelength between 260-400 nm and preferably, between 260-300 nm. The pressure of the lamp may be greater than 1.6 bar, 3 bar and preferably is 7 bar. The lamp may be composed of PS (synthetic quartz).


An ultraviolet (UV) liquid disinfection system and method are described. The system includes a conduit to carry liquid to be disinfected, the conduit having an inlet to receive the liquid and an outlet to discharge the liquid; a UV source configured to illuminate the liquid within the conduit; a liquid salinity detector to measure a value indicative of the liquid salinity; and a controller coupled to the salinity detector and configured to receive from the liquid salinity detector the measured value and to determine a desired salinity-adjusted UV dose level based on the measured value and predetermined data correlating salinity levels to respective UV dose levels.


Some aspects of the invention may be related to an ultraviolet (UV) water disinfection system and a method of assembling such system. The system may be designed to treat, inactivate, disintegrate and/or remove at least two predetermined different types of contaminations. The system may include a chamber to carry the water containing the predetermined types of contaminations. The system may further include one or more first-type UV lamps having a first UV emission spectrum and one or more second-type UV lamps having a second UV emission spectrum different than the first spectrum. A location of the one or more first-type UV lamps and the one or more second-type UV lamps may be determined such that a combined UV impact function matches with a combined sensitivity response function of the two or more predetermined different types of contaminations in the water each having a different response function


Some demonstrative embodiments of the invention include an illumination-based liquid disinfection device (100). The disinfection device (100) includes a light transparent conduit (101) to carry a flowing liquid to be disinfected, the conduit (101) having an inlet (106) to receive the liquid and an outlet (108) to discharge the liquid, a substantially light transparent sleeve (102) having external dimensions smaller than the internal dimensions of the conduit (101), the sleeve (102) positioned within the conduit (101) substantially perpendicular to the axis of symmetry of the conduit (101) and a light source (104) positioned within the sleeve (102).


Some demonstrative embodiments of the invention include an illumination-based liquid disinfection device (100). The disinfection device (100) includes a light transparent conduit (101) to carry a flowing liquid to be disinfected, the conduit (101) having an inlet (106) to receive the liquid and an outlet (108) to discharge the liquid, a substantially light transparent sleeve (102) having external dimensions smaller than the internal dimensions of the conduit (101), the sleeve (102) positioned within the conduit (101) substantially perpendicular to the axis of symmetry of the conduit (101) and a light source (104) positioned within the sleeve (102).


Some demonstrative embodiments of the invention include an illumination-based liquid disinfection device. The disinfection device may include, for example, a light transparent conduit to carry a flowing liquid to be disinfected, the conduit having an inlet to receive the liquid and an outlet to discharge the liquid, a substantially light transparent sleeve having external dimensions smaller than the internal dimensions of the conduit, the sleeve positioned within the conduit substantially perpendicular to the axis of symmetry of the conduit and a light source positioned within the sleeve.


An ultraviolet (UV) liquid treatment apparatus is disclosed. The apparatus may include a conduit having an inlet to receive liquid to be treated and an outlet to discharge treated fluid, the conduit defining a plurality of liquid flow paths between the inlet and the outlet. The apparatus may further include an UV light emitting diode (LED) module array to illuminate the liquid, wherein the UV LED module array comprises a plurality of UV LED modules arranged on a curved surface of an array holder, such the UV LED module array is configured to generate a customized spatial light flux distribution within the conduit that matches the liquid flow paths so as to obtain a desired UV dose distribution.


Some demonstrative embodiments of the invention include an illumination-based liquid disinfection device. The disinfection device may include, for example, a light transparent conduit to carry a flowing liquid to be disinfected, the conduit having an inlet to receive the liquid and an outlet to discharge the liquid, a substantially light transparent sleeve having external dimensions smaller than the internal dimensions of the conduit, the sleeve positioned within the conduit substantially perpendicular to the axis of symmetry of the conduit and a light source positioned within the sleeve.

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