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Fermo, Italy

Barocci S.,ASUR Marche AV2 | Mancini A.,University of Chieti Pescara | Canovari B.,San Salvatore Hospital | Petrelli E.,San Salvatore Hospital | And 8 more authors.
New Microbiologica | Year: 2015

This report describes a case of meningitis caused by Listeria monocytogenes in a stem cell transplant recipient on immunosuppressive therapy for cutaneous chronic graft-versus host disease. A 59-year-old woman had undergone allogeneic stem cell transplantation (from a matched unrelated donor) 13 months previously for chronic lymphocytic leukemia. She was on regular hematologic follow-up. Though her previous malignancy has been in remission, she was immunosuppressed due to the pharmacological treatment. We describe a meningitis caused by a typical food-borne pathogen, dangerous in patients with impaired cell-mediated immunity. Moreover the bacterium had a multidrug resistance, a rare characteristic in clinical listeriosis. Rapid diagnosis and treatment are key factors in these cases. We chose ampicillin and rifampicin that allowed a complete resolution of the clinical manifestations. © 2015, Luigi Ponzio e figlio Editori. All rights reserved. Source

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