Assam Agricultural University
Jorhat, India

Assam Agricultural University is an agricultural university which was established in 1969 under the Assam Agricultural University Act 1968 January 2, 1969. The jurisdiction of the University extends to the entire State of Assam with regard to teaching, research and extension education in the field of agriculture and allied science. The University has a number of campuses with its headquarters at Borbheta, about 5 km from both bus station and railway station and 2 km from airport of the City of Jorhat. The city can be reached easily from Guwahati, the capital of Assam, by AirRail. The latitude, longitude and altitude of Jorhat are 26°44´N, 94°l0´E and 9l m. above mean sea level respectively.The objectives of the University are:To make provision for imparting education to the people in agriculture and other allied branches of learningTo further the advancement of learning and research in agriculture and other allied scienceTo undertake the extension of such science especially to the rural people of the state. Wikipedia.

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Das R.T.,Assam Agricultural University | Barua P.K.,Assam Agricultural University
Legume Research | Year: 2017

Twenty three advanced breeding lines of green gram, developed at different centres under the All-India Coordinated Research Project on MULLARP, were evaluated by growing them during summer to characterize the genotypes and to assess the magnitude of genetic diversity in the genotypes. Genetic dissimilarities as revealed by Euclidean distances ranged from 2.891 to 10.494. Maximum distance was observed between ML 1354 and MH 721. Based on Euclidean distances four clusters were formed. Cluster II was the largest, and was further divided into two sub-clusters, IIA and IIB, comprising of four and nine genotypes, respectively. Genotypes MH 709 and KM 2272 belonging to cluster I were closely placed as they shared most of the characters. But they could be distinguished with the help of characters like days to 50% flowering, position of pods in the plant and growth habit. Similarly, GM 04-02 and NM 1 in sub-cluster IIA were closely grouped, and they could be distinguished based on the characters leaf size and pod length. Similarly other closely grouped genotypes were also distinguishable on the basis of some characters. It was observed from the average Euclidean distances that ML 1354, SG 1, MH 721, SG 63-14 and MH 709 were divergent genotypes. These genotypes were potential parents in green gram breeding programme. © 2017, Agricultural Research Communication Centre. All rights reserved.

Jangra A.,National Institute of Pharmaceutical Education and Research | Lukhi M.M.,National Institute of Pharmaceutical Education and Research | Sulakhiya K.,National Institute of Pharmaceutical Education and Research | Baruah C.C.,Assam Agricultural University | Lahkar M.,Guwahati Medical College
European Journal of Pharmacology | Year: 2014

Numerous studies have demonstrated that inflammation, oxidative stress and altered level of neurotrophins are involved in the pathogenesis of depressive illness. Mangiferin, a C-glucosylxanthone is abundant in the stem and bark of Mangifera indica L. The compound has been shown to possess antioxidant, anti-inflammatory and immunomodulatory activities. The present study was performed to investigate the effect of mangiferin pretreatment on lipopolysaccharide-induced increased proinflammatory cytokines, oxidative stress and neurobehavioural abnormalities. Mice were challenged with lipopolysaccharide (0.83 mg/kg, i.p.) after 14 days of mangiferin (20 and 40 mg/kg, p.o.) pretreatment. Mangiferin pretreatment significantly ameliorated the anxiety-like behaviour as evident from the results of an elevated plus maze, light-dark box and open field test. Mangiferin pretreatment also improved the anhedonic behaviour as revealed by sucrose preference test and increased social interaction time. It also prevented the lipopolysaccharide-evoked depressive-like effect by reducing the immobility time in forced swim and tail suspension test. Lipopolysaccharide-induced elevated oxidative stress was decreased with mangiferin pretreatment due to its potential to increase reduced glutathione concentration, Superoxide dismutase and catalase activity and decrease lipid peroxidation and nitrite level in the hippocampus as well as in the prefrontal cortex. Mangiferin pretreatment also attenuated neuroinflammation by reducing the interleukin-1 beta (IL-1β) level in hippocampus and prefrontal cortex. In conclusion, our results demonstrated that mangiferin possessed antidepressant and anti-anxiety properties due to its ability to attenuate IL-1β level and oxidative stress evoked by intraperitoneal administration of lipopolysaccharide. Mangiferin may be a potential therapeutic agent for the treatment of depressive and anxiety illness. © 2014 Published by Elsevier B.V.

Nath B.,Indian Institute of Technology Guwahati | Barman N.N.,Assam Agricultural University | Kumar S.,Indian Institute of Technology Guwahati
Microbial Pathogenesis | Year: 2016

Newcastle disease virus (NDV) isolates recovered from different outbreaks in chicken flocks in Assam during 2014-15 were genotypically and pathotypically characterized. Nucleotide sequence analysis of fusion (F) and hemagglutinin protein genes showed a close similarity with genotype XIII strains of NDV. Amino acid sequence of F protein showed a virulent cleavage site 112R-R-Q-K-R-F117. Furthermore, pathogenicity test in one-day-old chicks and embryonated chicken eggs showed a virulent pathotype of the isolated NDV strains. The study will help us to understand the biology of circulating strains of NDV in Northeastern part of India. © 2015 Elsevier Ltd.

Borah B.K.,University of Delhi | Borah B.K.,Assam Agricultural University | Dasgupta I.,University of Delhi
Journal of Biosciences | Year: 2012

Begomoviruses are a large group of whitefly-transmitted plant viruses containing single-stranded circular DNA encapsidated in geminate particles. They are responsible for significant yield losses in a wide variety of crops in India. Research on begomoviruses has focussed on the molecular characterization of the viruses, their phylogenetic analyses, infectivities on host plants, DNA replication, transgenic resistance, promoter analysis and development of virus-based gene silencing vectors. There have been a number of reports of satellite molecules associated with begomoviruses. This article aims to summarize the major developments in begomoviral research in India in the last approximately 15 years and identifies future areas that need more attention. © Indian Academy of Sciences.

Neog M.,Regional Agricultural Research Station | Saikia L.,Assam Agricultural University
Journal of Food Science and Technology | Year: 2010

Pericarp browning is the major post-harvest problem of litchi (Litchi chinensis Sonn) fruit, resulting in reduced commercial value of the fruit. Control of postharvest pericarp browning of fruit using 9 different postharvest treatments were studied. The treated fruits were packed in transparent perforated (0.2% ventilation) low density polythene bags (100 gauge). On storage, pericarp browning increased irrespective of treatments with the decrease in pericarp specific activity, total pericarp phenol and total anthocyanin. Anthocyanin degradation index and polymeric colour increased during storage. Pre-cooled (100C) fruits treated with 0.6% sodium metabisulphite solution for 10 min, air dried followed by dipping in 2% HCl for 5 min and packing in perforated LDPE bags recorded the lowest polyphenol oxidase specific activity (2.2 units/mg protein) with maximum retention of total anthocyanin (47.3 mg/100g) leading to the lowest pericarp browning after 9 days of storage with attractive red colour, freshness and enhanced shelf life of 9 days at ambient conditions (27.7 ± 1.2°C, RH 78 ± 4%). © Association of Food Scientists and Technologists (India), Mysore.

Kasala E.R.,National Institute of Pharmaceutical Education and Research | Bodduluru L.N.,National Institute of Pharmaceutical Education and Research | Barua C.C.,Assam Agricultural University | Gogoi R.,National Institute of Pharmaceutical Education and Research
Chemico-Biological Interactions | Year: 2015

This letter illustrates the significant chemosensitizing effects of chrysin to resistance cancer cells and refers to the article on "Combination of chrysin and cisplatin promotes the apoptosis of Hep G2 cells by up-regulating p53" by Li et al., published in your journal recently. Recent studies have demonstrated that chrysin is able to sensitize or kill cancer cells which are resistant to chemotherapeutic drugs such as cisplatin, doxorubicin and adriamycin. Owing to its potential anti-cancer effects and devoid of toxicity to non-transformed cells, further research is required to completely explore its chemosensitizing effects in other cancers and also assess and evaluate its safety, before going for possible human application. © 2015 Elsevier Ireland Ltd. All rights reserved.

Kasala E.R.,National Institute of Pharmaceutical Education and Research | Bodduluru L.N.,National Institute of Pharmaceutical Education and Research | Madana R.M.,National Institute of Pharmaceutical Education and Research | Athira K.V.,National Institute of Pharmaceutical Education and Research | And 2 more authors.
Toxicology Letters | Year: 2015

Chrysin, a naturally occurring flavone, abundantly found in numerous plant extracts including propolis and in honey is one of the most widely used herbal medicine in Asian countries. Nowadays, chrysin has become the foremost candidate exhibiting health benefits, owing to its multiple bioactivities such as antioxidant, anti-inflammatory, anti-allergic, anti-diabetic, anti-estrogenic, antibacterial and antitumor activities. Anticancer activity is most promising among the multiple pharmacological effects displayed by chrysin. In vitro and in vivo models have shown that chrysin inhibits cancer growth through induction of apoptosis, alteration of cell cycle and inhibition of angiogenesis, invasion and metastasis without causing any toxicity and undesirable side effects to normal cells. Chrysin displays these effects through selective modulation of multiple cell signaling pathways which are linked to inflammation, survival, growth, angiogenesis, invasion and metastasis of cancer cells. This broad spectrum of antitumor activity in conjunction with low toxicity underscores the translational value of chrysin in cancer therapy. The present review highlights the chemopreventive and therapeutic effects, molecular targets and antineoplastic mechanisms that contribute to the observed anticancer activity of chrysin. © 2015 Elsevier Ireland Ltd.

Bodduluru L.N.,National Institute of Pharmaceutical Education and Research | Kasala E.R.,National Institute of Pharmaceutical Education and Research | Thota N.,National Institute of Pharmaceutical Education and Research | Barua C.C.,Assam Agricultural University | Sistla R.,Indian Institute of Chemical Technology
Toxicology in Vitro | Year: 2014

Cancer chemoprevention is a strategy taken to block, reverse or retard the multistep process of carcinogenesis, including the blockage of its vital morphogenetic milestones viz. normal-preneoplasia-neoplasia-metastasis. Naturally occurring phytochemicals are becoming increasingly popular over synthetic drugs for several reasons, including safety, efficacy and easy availability. Nimbolide, a triterpene derived from the leaves and flowers of neem, is widely used in traditional medical practices for treating various human ailments. The neem limonoid exhibits multiple pharmacological effects among which its anticancer activity is the most promising. The preclinical and mechanistic studies carried over the decades have shown that nimbolide inhibits tumorigenesis and metastasis without any toxicity and unwanted side effects. Nimbolide exhibits anticancer activity through selective modulation of multiple cell signaling pathways linked to inflammation, survival, growth, invasion, angiogenesis and metastasis. The present review highlights the current knowledge on molecular targets that contribute to the observed anticancer activity of nimbolide related to (i) inhibition of carcinogenic activation and induction of antioxidant and carcinogen detoxification enzymes, (ii) induction of growth arrest and apoptosis; and (iii) suppression of proinflammatory signaling pathways related to cancer progression. © 2014 Elsevier Ltd.

Gogoi B.,Assam Agricultural University
Indian Journal of Animal Research | Year: 2011

The effect of integrated nutrient management (INM) on soil properties and availability of nutrients after rainfed rice (Oryza sativa L.)-niger (Guizotia abyssinica L.) cropping sequence studied during 2006- 08 revealed that the application of 50% recommended dose of fertilizers (RDF) + 50% N (FYM) showed the lowest bulk density and the highest water holding capacity of soil. The above treatment was at par with 50% N (inorganic) + 50% N (FYM) + PK (inorganic and adjusted) i.e. T6. However, effect of integrated nutrient management had a non significant effect on pH of soil. At the end of the cropping sequence, significant soil organic carbon increased and higher available N, P2O5 and K2O of soil were observed when 50% recommended dose of fertilizers (inorganic) substituted through 50% N FYM (organic) over RDF and control.

Bonia K.K.,Assam Agricultural University
Indian Journal of Animal Research | Year: 2015

A total of ten normal cyclic and ten confirmed sub-oestrous cows yielding 10 – 20 liters of milk were selected at random for this study. Blood samples were collected from each animal on day 0, 5,10, 15 and 20 (day 0 of the next cycle) and each sample was analyzed for estimation of calcium, inorganic phosphorus, sodium, potassium, total protein, glucose, cholesterol, alkaline phosphatase, iron, magnesium, copper and zinc by using quality kits when cobalt was determined with the help of Atomic Absorption Spectrophometer. The result revealed that the mean serum concentrations of sodium, iron, copper and zinc, glucose, cholesterol and alkaline phosphatase varied significantly (P< 0.01) whereas mean values of potassium, magnesium and cobalt varied significantly (P < 0.05) at different days of both ostrous cycles. On the other hand, all mean levels of the biological constituents did not vary between normal and sub-oestrous cycles of the present stdudy. However, the variation of all biological constituents in serum remained within normal physiological levels in both normal and suboestrous cycle of crossbred cows of the present study. © 2015 Agricultural Research Communication Centre. All rights reserved.

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