Assam Agricultural University
Jorhat, India

Assam Agricultural University is an agricultural university which was established in 1969 under the Assam Agricultural University Act 1968 January 2, 1969. The jurisdiction of the University extends to the entire State of Assam with regard to teaching, research and extension education in the field of agriculture and allied science. The University has a number of campuses with its headquarters at Borbheta, about 5 km from both bus station and railway station and 2 km from airport of the City of Jorhat. The city can be reached easily from Guwahati, the capital of Assam, by AirRail. The latitude, longitude and altitude of Jorhat are 26°44´N, 94°l0´E and 9l m. above mean sea level respectively.The objectives of the University are:To make provision for imparting education to the people in agriculture and other allied branches of learningTo further the advancement of learning and research in agriculture and other allied scienceTo undertake the extension of such science especially to the rural people of the state. Wikipedia.

Time filter
Source Type

Rajkhowa D.J.,Assam Agricultural University
Pestology | Year: 2017

Ipomoea carnea, a highly invasive weed has spread rapidly through out the country in the last three decades. The weed has posed as a serious threat to agriculture and environment due to its faster growth, wider adaptability, lack of natural enemies and easy colonization habit. A single method is often failed to give satisfactory control of this weed for which an integrated strategy for containing this weed is very much necessary. Combination of preventive, mechanical, chemical as well as utilization of this weed for compost/vermicompost production seems to provide effective control of this weed. The tender stems and twigs of the weed can also be used as green leaf manure in transplanted rice.

Sarkar U.K.,ICAR Central Inland Fisheries Research Institute | Borah B.C.,Assam Agricultural University
Wetlands Ecology and Management | Year: 2017

Floodplain wetlands of India are biologically rich sensitive ecosystem that support unique aquatic biodiversity and play vital role in providing livelihood and nutritional security to a large section of the population of the country. Besides contributing to the environmental sustainability through Carbon sequestration, flood plain wetlands also serve as source for harvesting flood and rain water. Covering around 5.5 Lakh ha area, the flood plain wetlands of India are one of the major sources for fish production of the country, offering vast potential for capture as well as culture based fisheries. Degradation and shrinkage of the floodplain wetlands have been recorded due to several natural and anthropogenic reasons. In addition to that, the change in the climatic condition may have a far more devastating impact on these natural resources. Substantial change in climate with increasing temperature trend (0.60 °C during last 112 years) as well as changing pattern and intensity of rainfall have been reported in India. It is projected that extreme climate changes may have profound impact on wetlands, mediated through several direct or indirect pathways. Attention is urgently required at different levels for conservation and revamping of these resources along with coping up and mitigation strategies to address the impending challenges. However, there is dearth of scientific information specific to the flood plain wetlands of India. This paper reviews the present status and importance of the flood plain wetlands of India with special reference to impact of climate change along with coping-up and mitigation measures. © 2017 Springer Science+Business Media B.V.

Sriram C.S.,National Institute of Pharmaceutical Education and Research | Jangra A.,National Institute of Pharmaceutical Education and Research | Gurjar S.S.,National Institute of Pharmaceutical Education and Research | Mohan P.,Assam Agricultural University | And 2 more authors.
Physiology and Behavior | Year: 2016

Poly(ADP-ribose) polymerase-1 (PARP-1) is a DNA nick-sensor enzyme that functions at the center of cellular stress response and affects the immune system at several key points, and thus modulates inflammatory diseases. Our previous study demonstrated that lipopolysaccharide (LPS)-induced depressive-like behavior in mice can be ameliorated by 3-aminobenzamide, which is a PARP-1 inhibitor. In the present study we've examined the effect of a free radical scavenger, edaravone pretreatment against LPS-induced anxiety and depressive-like behavior as well as various hippocampal biochemical parameters including PARP-1. Male Swiss albino mice were treated with edaravone (3 & 10. mg/kg. i.p.) once daily for 14. days. On the 14th day 30. min after edaravone treatment mice were challenged with LPS (1. mg/kg. i.p.). After 3. h and 24. h of LPS administration we've tested mice for anxiety and depressive-like behaviors respectively. Western blotting analysis of PARP-1 in hippocampus was carried out after 12. h of LPS administration. Moreover, after 24. h of LPS administration serum corticosterone, hippocampal BDNF, oxido-nitrosative stress and pro-inflammatory cytokines were estimated by ELISA. Results showed that pretreatment of edaravone (10. mg/kg) ameliorates LPS-induced anxiety and depressive-like behavior. Western blotting analysis showed that LPS-induced anomalous expression of PARP-1 significantly reverses by the pretreatment of edaravone (10. mg/kg).Biochemical analyses revealed that LPS significantly diminishes BDNF, increases pro-inflammatory cytokines and oxido-nitrosative stress in the hippocampus. However, pretreatment with edaravone (10. mg/kg) prominently reversed all these biochemical alterations. Our study emphasized that edaravone pretreatment prevents LPS-induced anxiety and depressive-like behavior, mainly by impeding the inflammation, oxido-nitrosative stress and PARP-1 overexpression. © 2015.

Deka S.D.,Assam Agricultural University
Electronic Journal of Plant Breeding | Year: 2017

Germplasm characterization is an important link between the conservation and utilization of plant genetic resources. Genetic diversity within and between crops is a major requirement for plant breeders. For description of plant genetic recourses the choice of characteristics is crucial. In the present study 60 cultivated Capsicum annum varieties collected from different parts of India and their divergence and similarities were recorded for 35taxonomic traits. Variability for the 35 morpho physiological traits was evident .Traits suitable for identification and grouping of the Capsicum genotypes has been identified. Traits with variable phenotypic classes giving stable expression were -seedling- anthocyanin coloration of hypocotyl, plant shortened internodes (in upper part), anthocianin coloration of the nodes, varieties with shortened internodes, leaf shape and blistering, anthocianin coloration of anther, fruit color before maturity, fruit shape in longitudinal section, fruit attitude, peduncle attitude, shape of apex of the fruit and fruit colour at maturity.

Kasala E.R.,National Institute of Pharmaceutical Education and Research | Bodduluru L.N.,National Institute of Pharmaceutical Education and Research | Barua C.C.,Assam Agricultural University | Gogoi R.,National Institute of Pharmaceutical Education and Research
Biomedicine and Pharmacotherapy | Year: 2016

The present study is designed to assess the antioxidant and antitumor potential of luteolin against benzo(a)pyrene [B(a)P]-induced lung carcinogenesis in Swiss albino mice. Here, we reported that oral administration of B(a)P (50 mg/kg body weight) to mice resulted in raised lipid peroxides (LPO), lung specific tumor markers such as carcinoembryonic antigen (CEA) and neuron specific enolase (NSE) with concomitant decrease in the levels of both enzymatic antioxidants such as superoxide dismutase (SOD), catalase (CAT), glutathione reductase (GR), glutathione peroxidase (GPx) and glutathione-s-transferase (GST), and non-enzymatic antioxidants such as reduced glutathione (GSH), vitamin E and vitamin C. Luteolin treatment (15 mg/kg body weight, p.o) significantly counteracted all these alterations and maintained cellular normalcy. Moreover, assessment of protein expression levels by western blot analysis revealed that luteolin treatment effectively negates B(a)P-induced upregulated expression of proliferating cell nuclear antigen (PCNA), cytochrome P450 1A1 (CYP1A1) and nuclear factor-kappa B (NF-κB). Furthermore, histopathology of lung tissue and immunohistochemistry of CYP1A1 were carried out to substantiate the anti- lung cancer effect of luteolin. Overall, these findings confirm the chemopreventive potential of luteolin against B(a)P induced lung carcinogenesis. © 2016 Elsevier Masson SAS.

Jangra A.,National Institute of Pharmaceutical Education and Research | Lukhi M.M.,National Institute of Pharmaceutical Education and Research | Sulakhiya K.,National Institute of Pharmaceutical Education and Research | Baruah C.C.,Assam Agricultural University | Lahkar M.,Guwahati Medical College
European Journal of Pharmacology | Year: 2014

Numerous studies have demonstrated that inflammation, oxidative stress and altered level of neurotrophins are involved in the pathogenesis of depressive illness. Mangiferin, a C-glucosylxanthone is abundant in the stem and bark of Mangifera indica L. The compound has been shown to possess antioxidant, anti-inflammatory and immunomodulatory activities. The present study was performed to investigate the effect of mangiferin pretreatment on lipopolysaccharide-induced increased proinflammatory cytokines, oxidative stress and neurobehavioural abnormalities. Mice were challenged with lipopolysaccharide (0.83 mg/kg, i.p.) after 14 days of mangiferin (20 and 40 mg/kg, p.o.) pretreatment. Mangiferin pretreatment significantly ameliorated the anxiety-like behaviour as evident from the results of an elevated plus maze, light-dark box and open field test. Mangiferin pretreatment also improved the anhedonic behaviour as revealed by sucrose preference test and increased social interaction time. It also prevented the lipopolysaccharide-evoked depressive-like effect by reducing the immobility time in forced swim and tail suspension test. Lipopolysaccharide-induced elevated oxidative stress was decreased with mangiferin pretreatment due to its potential to increase reduced glutathione concentration, Superoxide dismutase and catalase activity and decrease lipid peroxidation and nitrite level in the hippocampus as well as in the prefrontal cortex. Mangiferin pretreatment also attenuated neuroinflammation by reducing the interleukin-1 beta (IL-1β) level in hippocampus and prefrontal cortex. In conclusion, our results demonstrated that mangiferin possessed antidepressant and anti-anxiety properties due to its ability to attenuate IL-1β level and oxidative stress evoked by intraperitoneal administration of lipopolysaccharide. Mangiferin may be a potential therapeutic agent for the treatment of depressive and anxiety illness. © 2014 Published by Elsevier B.V.

Nath B.,Indian Institute of Technology Guwahati | Barman N.N.,Assam Agricultural University | Kumar S.,Indian Institute of Technology Guwahati
Microbial Pathogenesis | Year: 2016

Newcastle disease virus (NDV) isolates recovered from different outbreaks in chicken flocks in Assam during 2014-15 were genotypically and pathotypically characterized. Nucleotide sequence analysis of fusion (F) and hemagglutinin protein genes showed a close similarity with genotype XIII strains of NDV. Amino acid sequence of F protein showed a virulent cleavage site 112R-R-Q-K-R-F117. Furthermore, pathogenicity test in one-day-old chicks and embryonated chicken eggs showed a virulent pathotype of the isolated NDV strains. The study will help us to understand the biology of circulating strains of NDV in Northeastern part of India. © 2015 Elsevier Ltd.

Neog M.,Regional Agricultural Research Station | Saikia L.,Assam Agricultural University
Journal of Food Science and Technology | Year: 2010

Pericarp browning is the major post-harvest problem of litchi (Litchi chinensis Sonn) fruit, resulting in reduced commercial value of the fruit. Control of postharvest pericarp browning of fruit using 9 different postharvest treatments were studied. The treated fruits were packed in transparent perforated (0.2% ventilation) low density polythene bags (100 gauge). On storage, pericarp browning increased irrespective of treatments with the decrease in pericarp specific activity, total pericarp phenol and total anthocyanin. Anthocyanin degradation index and polymeric colour increased during storage. Pre-cooled (100C) fruits treated with 0.6% sodium metabisulphite solution for 10 min, air dried followed by dipping in 2% HCl for 5 min and packing in perforated LDPE bags recorded the lowest polyphenol oxidase specific activity (2.2 units/mg protein) with maximum retention of total anthocyanin (47.3 mg/100g) leading to the lowest pericarp browning after 9 days of storage with attractive red colour, freshness and enhanced shelf life of 9 days at ambient conditions (27.7 ± 1.2°C, RH 78 ± 4%). © Association of Food Scientists and Technologists (India), Mysore.

Kasala E.R.,National Institute of Pharmaceutical Education and Research | Bodduluru L.N.,National Institute of Pharmaceutical Education and Research | Madana R.M.,National Institute of Pharmaceutical Education and Research | Athira K.V.,National Institute of Pharmaceutical Education and Research | And 2 more authors.
Toxicology Letters | Year: 2015

Chrysin, a naturally occurring flavone, abundantly found in numerous plant extracts including propolis and in honey is one of the most widely used herbal medicine in Asian countries. Nowadays, chrysin has become the foremost candidate exhibiting health benefits, owing to its multiple bioactivities such as antioxidant, anti-inflammatory, anti-allergic, anti-diabetic, anti-estrogenic, antibacterial and antitumor activities. Anticancer activity is most promising among the multiple pharmacological effects displayed by chrysin. In vitro and in vivo models have shown that chrysin inhibits cancer growth through induction of apoptosis, alteration of cell cycle and inhibition of angiogenesis, invasion and metastasis without causing any toxicity and undesirable side effects to normal cells. Chrysin displays these effects through selective modulation of multiple cell signaling pathways which are linked to inflammation, survival, growth, angiogenesis, invasion and metastasis of cancer cells. This broad spectrum of antitumor activity in conjunction with low toxicity underscores the translational value of chrysin in cancer therapy. The present review highlights the chemopreventive and therapeutic effects, molecular targets and antineoplastic mechanisms that contribute to the observed anticancer activity of chrysin. © 2015 Elsevier Ireland Ltd.

Bodduluru L.N.,National Institute of Pharmaceutical Education and Research | Kasala E.R.,National Institute of Pharmaceutical Education and Research | Thota N.,National Institute of Pharmaceutical Education and Research | Barua C.C.,Assam Agricultural University | Sistla R.,Indian Institute of Chemical Technology
Toxicology in Vitro | Year: 2014

Cancer chemoprevention is a strategy taken to block, reverse or retard the multistep process of carcinogenesis, including the blockage of its vital morphogenetic milestones viz. normal-preneoplasia-neoplasia-metastasis. Naturally occurring phytochemicals are becoming increasingly popular over synthetic drugs for several reasons, including safety, efficacy and easy availability. Nimbolide, a triterpene derived from the leaves and flowers of neem, is widely used in traditional medical practices for treating various human ailments. The neem limonoid exhibits multiple pharmacological effects among which its anticancer activity is the most promising. The preclinical and mechanistic studies carried over the decades have shown that nimbolide inhibits tumorigenesis and metastasis without any toxicity and unwanted side effects. Nimbolide exhibits anticancer activity through selective modulation of multiple cell signaling pathways linked to inflammation, survival, growth, invasion, angiogenesis and metastasis. The present review highlights the current knowledge on molecular targets that contribute to the observed anticancer activity of nimbolide related to (i) inhibition of carcinogenic activation and induction of antioxidant and carcinogen detoxification enzymes, (ii) induction of growth arrest and apoptosis; and (iii) suppression of proinflammatory signaling pathways related to cancer progression. © 2014 Elsevier Ltd.

Loading Assam Agricultural University collaborators
Loading Assam Agricultural University collaborators