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Jorhat, India

Assam Agricultural University is an agricultural university which was established in 1969 under the Assam Agricultural University Act 1968 January 2, 1969. The jurisdiction of the University extends to the entire State of Assam with regard to teaching, research and extension education in the field of agriculture and allied science. The University has a number of campuses with its headquarters at Borbheta, about 5 km from both bus station and railway station and 2 km from airport of the City of Jorhat. The city can be reached easily from Guwahati, the capital of Assam, by Air/Road/Rail. The latitude, longitude and altitude of Jorhat are 26°44´N, 94°l0´E and 9l m. above mean sea level respectively.The objectives of the University are:To make provision for imparting education to the people in agriculture and other allied branches of learningTo further the advancement of learning and research in agriculture and other allied scienceTo undertake the extension of such science especially to the rural people of the state. Wikipedia.

Bonia K.K.,Assam Agricultural University
Indian Journal of Animal Research | Year: 2015

A total of ten normal cyclic and ten confirmed sub-oestrous cows yielding 10 – 20 liters of milk were selected at random for this study. Blood samples were collected from each animal on day 0, 5,10, 15 and 20 (day 0 of the next cycle) and each sample was analyzed for estimation of calcium, inorganic phosphorus, sodium, potassium, total protein, glucose, cholesterol, alkaline phosphatase, iron, magnesium, copper and zinc by using quality kits when cobalt was determined with the help of Atomic Absorption Spectrophometer. The result revealed that the mean serum concentrations of sodium, iron, copper and zinc, glucose, cholesterol and alkaline phosphatase varied significantly (P< 0.01) whereas mean values of potassium, magnesium and cobalt varied significantly (P < 0.05) at different days of both ostrous cycles. On the other hand, all mean levels of the biological constituents did not vary between normal and sub-oestrous cycles of the present stdudy. However, the variation of all biological constituents in serum remained within normal physiological levels in both normal and suboestrous cycle of crossbred cows of the present study. © 2015 Agricultural Research Communication Centre. All rights reserved. Source

Kasala E.R.,National Institute of Pharmaceutical Education and Research | Bodduluru L.N.,National Institute of Pharmaceutical Education and Research | Madana R.M.,National Institute of Pharmaceutical Education and Research | Athira K.V.,National Institute of Pharmaceutical Education and Research | And 2 more authors.
Toxicology Letters | Year: 2015

Chrysin, a naturally occurring flavone, abundantly found in numerous plant extracts including propolis and in honey is one of the most widely used herbal medicine in Asian countries. Nowadays, chrysin has become the foremost candidate exhibiting health benefits, owing to its multiple bioactivities such as antioxidant, anti-inflammatory, anti-allergic, anti-diabetic, anti-estrogenic, antibacterial and antitumor activities. Anticancer activity is most promising among the multiple pharmacological effects displayed by chrysin. In vitro and in vivo models have shown that chrysin inhibits cancer growth through induction of apoptosis, alteration of cell cycle and inhibition of angiogenesis, invasion and metastasis without causing any toxicity and undesirable side effects to normal cells. Chrysin displays these effects through selective modulation of multiple cell signaling pathways which are linked to inflammation, survival, growth, angiogenesis, invasion and metastasis of cancer cells. This broad spectrum of antitumor activity in conjunction with low toxicity underscores the translational value of chrysin in cancer therapy. The present review highlights the chemopreventive and therapeutic effects, molecular targets and antineoplastic mechanisms that contribute to the observed anticancer activity of chrysin. © 2015 Elsevier Ireland Ltd. Source

Bodduluru L.N.,National Institute of Pharmaceutical Education and Research | Kasala E.R.,National Institute of Pharmaceutical Education and Research | Thota N.,National Institute of Pharmaceutical Education and Research | Barua C.C.,Assam Agricultural University | Sistla R.,Indian Institute of Chemical Technology
Toxicology in Vitro | Year: 2014

Cancer chemoprevention is a strategy taken to block, reverse or retard the multistep process of carcinogenesis, including the blockage of its vital morphogenetic milestones viz. normal-preneoplasia-neoplasia-metastasis. Naturally occurring phytochemicals are becoming increasingly popular over synthetic drugs for several reasons, including safety, efficacy and easy availability. Nimbolide, a triterpene derived from the leaves and flowers of neem, is widely used in traditional medical practices for treating various human ailments. The neem limonoid exhibits multiple pharmacological effects among which its anticancer activity is the most promising. The preclinical and mechanistic studies carried over the decades have shown that nimbolide inhibits tumorigenesis and metastasis without any toxicity and unwanted side effects. Nimbolide exhibits anticancer activity through selective modulation of multiple cell signaling pathways linked to inflammation, survival, growth, invasion, angiogenesis and metastasis. The present review highlights the current knowledge on molecular targets that contribute to the observed anticancer activity of nimbolide related to (i) inhibition of carcinogenic activation and induction of antioxidant and carcinogen detoxification enzymes, (ii) induction of growth arrest and apoptosis; and (iii) suppression of proinflammatory signaling pathways related to cancer progression. © 2014 Elsevier Ltd. Source

Borah B.K.,University of Delhi | Borah B.K.,Assam Agricultural University | Dasgupta I.,University of Delhi
Journal of Biosciences | Year: 2012

Begomoviruses are a large group of whitefly-transmitted plant viruses containing single-stranded circular DNA encapsidated in geminate particles. They are responsible for significant yield losses in a wide variety of crops in India. Research on begomoviruses has focussed on the molecular characterization of the viruses, their phylogenetic analyses, infectivities on host plants, DNA replication, transgenic resistance, promoter analysis and development of virus-based gene silencing vectors. There have been a number of reports of satellite molecules associated with begomoviruses. This article aims to summarize the major developments in begomoviral research in India in the last approximately 15 years and identifies future areas that need more attention. © Indian Academy of Sciences. Source

Nath B.,Indian Institute of Technology Guwahati | Barman N.N.,Assam Agricultural University | Kumar S.,Indian Institute of Technology Guwahati
Microbial Pathogenesis | Year: 2016

Newcastle disease virus (NDV) isolates recovered from different outbreaks in chicken flocks in Assam during 2014-15 were genotypically and pathotypically characterized. Nucleotide sequence analysis of fusion (F) and hemagglutinin protein genes showed a close similarity with genotype XIII strains of NDV. Amino acid sequence of F protein showed a virulent cleavage site 112R-R-Q-K-R-F117. Furthermore, pathogenicity test in one-day-old chicks and embryonated chicken eggs showed a virulent pathotype of the isolated NDV strains. The study will help us to understand the biology of circulating strains of NDV in Northeastern part of India. © 2015 Elsevier Ltd. Source

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