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Piedmont, Italy

D'Ovidio F.,University of Turin | d'Errico A.,ASL TO | Scarinzi C.,ARPA Piedmont | Costa G.,University of Turin
Social Science and Medicine

Objective of this study was to assess the risk of coronary heart disease (CHD) associated with the combination of employment status and child care among women of working age, also examining the sex of the offspring. Only two previous studies investigated the effect of double burden on CHD, observing an increased risk among employed women with high domestic burden or providing child care, although the relative risks were marginally or not significant.The study population was composed of all women 25-50 years old at 2001 census, living in Turin in families composed only by individuals or couples, with or without children (N=109,358). Subjects were followed up during 2002-2010 for CHD incidence and mortality through record-linkage of the cohort with the local archives of mortality and hospital admissions. CHD risk was estimated by multivariate Poisson regression models.Among employed women, CHD risk increased significantly by 29% for each child in the household (IRR=1.29) and by 39% for each son (IRR=1.39), whereas no association with the presence of children was found among non-employed women or among employed women with daughters. When categorized, the presence of two or more sons significantly increased CHD risk among employed women (IRR=2.23), compared to those without children.The study found a significant increase in CHD risk associated with the presence of two or more sons in the household, but not daughters, among employed women. This is a new finding, which should be confirmed in other studies, conducted also in countries where the division of domestic duties between males and females is more balanced, such as the European Nordic countries. © 2015 Elsevier Ltd. Source

Civardi C.,NeuroLogica | Pisano F.,Neurologia Riabilitativa | Delconte C.,Neurologia Riabilitativa | Collini A.,ASL TO | Monaco F.,NeuroLogica
Neurological Sciences

Corticobasal syndrome is characterized by asymmetric cortical sensorimotor dysfunction and parkinsonism; an altered cortical excitability has been reported. We explored with transcranial magnetic stimulation the motor cortical excitability in corticobasal syndrome, and the effects of slow repetitive transcranial magnetic stimulation. With transcranial magnetic stimulation, we studied two corticobasal syndrome patients. We determined bilaterally from the first dorsal interosseous muscle: relaxed threshold, and contralateral and ipsilateral silent period. We also evaluated the contralateral silent period after active/sham slow repetitive transcranial magnetic stimulation on the most affected side. At T0 the silent period was bilaterally short. On the most affected side, active slow repetitive transcranial magnetic stimulation induced a short lasting prolongation of the contralateral silent period. In corticobasal syndrome, transcranial magnetic stimulation showed a reduction cortical inhibitory phenomenon potentially reversed transiently by slow repetitive transcranial magnetic stimulation. © 2015, Springer-Verlag Italia. Source

Catuzzo P.,Valle dAosta Regional Hospital | Aimonetto S.,Valle dAosta Regional Hospital | Zenone F.,Valle dAosta Regional Hospital | Fanelli G.,Valle dAosta Regional Hospital | And 4 more authors.
British Journal of Radiology

Recent and continuous advances in CT, such as the development of multislice CT, have promoted a rapid increase in its clinical application. Today, CT accounts for approximately 10% of the total number of medical radiographic procedures worldwide. However, the growing performance of the new CT generations have increased not only the diagnostic opportunities, but also the radiation dose to the patient. The relative contribution to the collective radiation dose is now estimated to be approximately 50%. Several papers have been published concerning the intensive use of CT and its contribution to the collective dose. However, most of the literature concerns the years 1997-2003 and the dosimetric evaluations are generally limited to the main standard protocols (chest, head and abdomen), deriving the effective dose by the simple application of the diagnostic reference levels. Only specific dosimetric analyses of single and innovative procedures have been published recently. Moreover, few data comes from Italian radiology departments. This paper aims to bridge these gaps. Firstly, it characterises in terms of measured CT dose index (CTDI) two last-generation scanners of the Radiological Department of Aosta Hospital. Secondly, it evaluates the effective dose from most of the CT examinations performed from 2001 to 2008 to compare protocols and technologies in line with the suggestions of the 2007 Recommendations of the International Commission on Radiological Protection, Publication 103. Finally, it estimates the collective dose to the population. © 2010 The British Institute of Radiology. Source

Lioce E.,University of Turin | Milani P.,University of Turin | Bistolfi A.,Traumatology and Rehabilitation | Capacchione P.,University of Turin | And 2 more authors.
Disability and Rehabilitation

Purpose: Incontinentia pigmenti (IP), or Bloch-Sulzberger syndrome, is a rare X-linked dominant genetic disorder with multisystem involvement. To our knowledge, there are no previous reports about rehabilitation in IP adult with intact cognitive development. We report a 20-year-old lady with IP managed and followed into adulthood. Method: Patient management and rehabilitation programs from birth to the last follow-up. Results: There was normal cognitive development despite magnetic resonance imaging (MRI) evidence of white matter, corpus callosum and brainstem hypoplasia. Extensor spasticity was present on both lower limbs for which she underwent rehabilitation from the age of one. Botulinum toxin injections were performed and when she was 15 years old she underwent functional surgery. Conclusion: The absence of mental retardation in our patient enabled us to carry out an active rehabilitation program and provide her with maximum independence in locomotion and in activities of daily living.Implications for RehabiliationIncontinentia pigmenti (Bloch-Sulzberger syndrome).Incontinentia pigmenti is a rare X-linked dominant genetic disorder with multisystemic involvement.Skin lesions, neurological impairments, motormental retardation, skeletal congenital defects and ophthalmologic involvement are IP most frequent manifestations.Due to the complex multisystem involvement resulting in severe long-term disability, patients with IP require a multidisciplinary team approach for rehabilitation.In IP patients, rehabilitation interventions should always take into consideration the individual phenotype expression, child's physical development and personal needs. © 2014 Informa UK Ltd. All rights reserved: reproduction in whole or part not permitted. Source

Picci R.L.,University of Turin | Versino E.,University of Turin | Oliva F.,University of Turin | Giaretto R.M.,University of Turin | And 4 more authors.
Psychiatry Research

Although several papers reported a wide range of negative outcomes among patients with both schizophrenia and Substance Use Disorder (SUD), only a few studies evaluated the impact of SUD on psychopathology and thus on the length of first-hospitalization. The aim of the present study was to compare clinical expression of first-episode of schizophrenia between inpatients with and without SUD, giving close attention to the length of stay. One hundred and thirty inpatients at first-episode of schizophrenia were assigned to either SUD or not SUD group depending on SUD diagnosis and were assessed through BPRS at admission, during hospitalization and at discharge. Cross-sectional and longitudinal statistical analysis were performed to investigate differences between groups and also a linear regression was used to evaluate relationship between length of stay and BPRS scores. SUD group showed more disorganization at admission, less marked improvement of symptoms (disorganization, thought disturbance, anergia), and longer hospital stay than not SUD group. Moreover BPRS total score during hospitalization was a significant positive predictor for length of stay. Taken together, these findings suggest that SUD patients have a more severe and drug-resistant expression of schizophrenia, hence, they need longer treatment to achieve the overall symptoms improvement required for discharge. © 2013 Elsevier Ireland Ltd. Source

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