General Hospital Asklipieio Voulas

Athens, Greece

General Hospital Asklipieio Voulas

Athens, Greece

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Kontodimopoulos N.,Hellenic Open University | Bozios P.,Hellenic Open University | Bozios P.,General Hospital Asklipieio Voulas | Yfantopoulos J.,Hellenic Open University | And 2 more authors.
European Journal of Health Economics | Year: 2013

Objectives: The purpose of this methodological study was to to provide insight into the under-addressed issue of the longitudinal predictive ability of mapping models. Post-intervention predicted and reported utilities were compared, and the effect of disease severity on the observed differences was examined. Methods: A cohort of 120 rheumatoid arthritis (RA) patients (60.0% female, mean age 59.0) embarking on therapy with biological agents completed the Modified Health Assessment Questionnaire (MHAQ) and the EQ-5D at baseline, and at 3, 6 and 12 months post-intervention. OLS regression produced a mapping equation to estimate post-intervention EQ-5D utilities from baseline MHAQ data. Predicted and reported utilities were compared with t test, and the prediction error was modeled, using fixed effects, in terms of covariates such as age, gender, time, disease duration, treatment, RF, DAS28 score, predicted and reported EQ-5D. Results: The OLS model (RMSE = 0.207, R 2 = 45.2%) consistently underestimated future utilities, with a mean prediction error of 6.5%. Mean absolute differences between reported and predicted EQ-5D utilities at 3, 6 and 12 months exceeded the typically reported MID of the EQ-5D (0.03). According to the fixed-effects model, time, lower predicted EQ-5D and higher DAS28 scores had a significant impact on prediction errors, which appeared increasingly negative for lower reported EQ-5D scores, i.e.; predicted utilities tended to be lower than reported ones in more severe health states. Conclusions: This study builds upon existing research having demonstrated the potential usefulness of mapping disease-specific instruments onto utility measures. The specific issue of longitudinal validity is addressed, as mapping models derived from baseline patients need to be validated on post-therapy samples. The underestimation of post-treatment utilities in the present study, at least in more severe patients, warrants further research before it is prudent to conduct cost-utility analyses in the context of RA by means of the MHAQ alone. © 2012 Springer-Verlag.


Dimitriou A.,National and Kapodistrian University of Athens | Perisanidis C.,Medical University of Vienna | Chalkiadakis V.,General Hospital Asklipieio Voulas | Marangoudakis P.,National and Kapodistrian University of Athens | And 2 more authors.
International Journal of Pediatric Otorhinolaryngology | Year: 2016

Objectives Newborn hearing screening programs are already implemented in many countries worldwide. Nonetheless there is still no consensus about the most proper post-birth day of examination. The purpose of this study was to assess the most appropriate day of universal hearing screening program in a public hospital. Material and methods A prospective cohort study was conducted in “Attiko University National Health System Hospital” and included 2494 newborns. They were examined before discharge from the hospital, using transient evoked otoacoustic emissions (TEOAEs). Results From 2494 neonates included in the study, 2129 (85.4%) bilaterally passed the screening examination, while 365 (14.6%) failed the test. Higher levels of “pass” result per day of life were presented the third (90%) and fourth (94%) day of life. These days the referral scores were lower, reaching 6% the 4th post-birth day. Conclusion All infants should be screened for their hearing in the first days of life as otoacoustic emissions can be recorded from the first 24 h of life. If the babies stay in the maternity unit for more that 1–2 days for any reason (protocol of the maternity unit, parents leave in remote areas, etc.) we recommend the 4th day of life as the most appropriate day of examination in order to minimize the false positive (“refer”) results at the initial examination. © 2016 Elsevier Ireland Ltd


PubMed | General Hospital Asklipieio Voulas, National and Kapodistrian University of Athens and Medical University of Vienna
Type: | Journal: International journal of pediatric otorhinolaryngology | Year: 2016

Newborn hearing screening programs are already implemented in many countries worldwide. Nonetheless there is still no consensus about the most proper post-birth day of examination. The purpose of this study was to assess the most appropriate day of universal hearing screening program in a public hospital.A prospective cohort study was conducted in Attiko University National Health System Hospital and included 2494 newborns. They were examined before discharge from the hospital, using transient evoked otoacoustic emissions (TEOAEs).From 2494 neonates included in the study, 2129 (85.4%) bilaterally passed the screening examination, while 365 (14.6%) failed the test. Higher levels of pass result per day of life were presented the third (90%) and fourth (94%) day of life. These days the referral scores were lower, reaching 6% the 4th post-birth day.All infants should be screened for their hearing in the first days of life as otoacoustic emissions can be recorded from the first 24h of life. If the babies stay in the maternity unit for more that 1-2 days for any reason (protocol of the maternity unit, parents leave in remote areas, etc.) we recommend the 4th day of life as the most appropriate day of examination in order to minimize the false positive (refer) results at the initial examination.


Vagka E.,Technological Educational Institute of Athens | Notara V.,Technological Educational Institute of Athens | Argirou A.,Psychiatric Hospital of Athens Dromokaiteio | Gotsidou F.,Psychiatric Hospital of Athens Dromokaiteio | And 3 more authors.
Epitheorese Klinikes Farmakologias kai Farmakokinetikes | Year: 2011

The success or failure of an individual to cope with stressful situations, undermine his cognitive performance. Aim: The objective of this study was to examine college students' anxiety symptoms during the exam. The aim was to familiarize the academic community regarding the existence of students' anxiety so as to redraw new strategies of knowledge acquisition. Material - Method: Study sample consisted of 300 students, randomly selected from the School of Health and Welfare of the Technological Educational Institute of Athens (A.T.E.I.) of all years. The interviews were based on the scale of Nist and Diehl (1990). The SPSS version 15 software was used for the statistical analysis, whereas descriptive statistics were applied to analysing the data. The results were evaluated on preprinted scores. Results: Symptoms, such as sweaty palms, shaky hands, abdominal pains, nausea and panic before exams appeared, mainly, in the answers of rarely and sometimes whereas in the answer of always the percentage was lower. The same picture appeared in the answers concerning their psychological condition during the exam process. The results, based on preprinted scores, indicated that 28% of the respondents had no anxiety, 61.5% had a basal anxiety, while 10.5% had a higher mean anxiety score. Conclusions: This study indicates a moderate level of exam anxiety, however the 10.5% with high level of anxiety should not be underestimated. Therefore it is recommended that modifications and improvements in students' performance are needed, so as to develop critical thinking, to increase attentiveness and concentration, to enhance emotional intelligence and to optimize learning skills.


Chalkiadakis V.,General Hospital Asklipieio Voulas | Roukis G.,General Hospital Asklipieio Voulas | Karatzias G.,General Hospital Asklipieio Voulas | Androulakis M.,General Hospital Asklipieio Voulas
Otorhinolaryngology Clinics | Year: 2015

A retropharyngeal abscess is an infection in the deep space of the neck and it is a potentially life-threatening condition, because of severe complications. Today, it is rare in adults, but it is still present in immunosuppressed patients or after local trauma by foreign body. Diagnosis is challenging due to the variety of the symptoms and a computed tomography (CT) scan of the area is required. Its management requires highly specialized care, based on antibiotic therapy and surgical drainage of the abscess. We report a case of a retropharyngeal abscess in a diabetic patient, with renal nephropathy and end-stage renal failure. Interestingly, the abscess was inside the thoracic cavity and surgical procedure included also thoracotomy. © 2015, Jaypee Brothers Medical Publishers (P) Ltd. All rights reserved.

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