Asbury University, formerly Asbury College, is a Christian liberal arts institution located in Wilmore, Kentucky, United States. Although it is a nondenominational school, the college's foundation stems from a Wesleyan-Holiness tradition. The school offers 50 majors across 17 departments. Primarily a four-year college, Asbury was ranked in the third tier of liberal arts colleges by U.S. News & World Report in 2008. Asbury University's freshman retention rate is above 85 percent. Approximately 34 percent of incoming freshmen are in the top 10 percent of their high school classes, and more than 80 percent of current faculty are full-time.The campus of Asbury Theological Seminary, which became a separate institution in 1940, is located across the street from Asbury University.Asbury University is a member of the Christian College Consortium and the Council for Christian Colleges and Universities.In the fall of 2012, Asbury University had a total enrollment of 1,764: 1,325 traditional undergraduate students, 203 adult degree completion students, and 236 graduate students. Wikipedia.
News Article | March 2, 2017
The Community for Accredited Online Schools, a leading resource provider for higher education information, has compiled a list of the best colleges and universities with online programs in Kentucky for 2017. Of the 20 four-year schools that were ranked, University of Kentucky, University of Louisville, Eastern Kentucky University, Murray State University and Western Kentucky University came in as the top five institutions. The top 16 two-year schools were also included, with West Kentucky Community and Technical College, Maysville Community and Technical College, Bluegrass Community and Technical College, Jefferson Community and Technical College and Somerset Community College named as the top five. “The schools on our list have been evaluated based on more than a dozen unique data points,” said Doug Jones, CEO and founder of AccreditedSchoolsOnline.org. “The results is a selection of the best online curriculum, program variety, student resources and graduation outcomes in Kentucky.” To earn a spot on the Best Online Schools list, colleges and universities in Kentucky must be institutionally accredited, public or private not-for-profit entities. Each college is also judged based on such criteria as student/teacher ratios, employment services, student resources, graduation rates and financial aid availability. For more details on where each school falls in the rankings and the data and methodology used to determine the lists, visit: The Best Online Four-Year Schools in Kentucky for 2017 include the following: Asbury University Brescia University Campbellsville University Eastern Kentucky University Georgetown College Kentucky Christian University Kentucky State University Kentucky Wesleyan College Lindsey Wilson College Midway College Morehead State University Murray State University Northern Kentucky University The Southern Baptist Theological Seminary Thomas More College Union College University of Kentucky University of Louisville University of the Cumberlands Western Kentucky University Kentucky’s Best Online Two-Year Schools for 2017 include the following: Ashland Community and Technical College Big Sandy Community and Technical College Bluegrass Community and Technical College Elizabethtown Community and Technical College Gateway Community and Technical College Hazard Community and Technical College Henderson Community College Hopkinsville Community College Jefferson Community and Technical College Madisonville Community College Maysville Community and Technical College Owensboro Community and Technical College Somerset Community College Southcentral Kentucky Community and Technical College Southeast Kentucky Community and Technical College West Kentucky Community and Technical College About Us: AccreditedSchoolsOnline.org was founded in 2011 to provide students and parents with quality data and information about pursuing an affordable, quality education that has been certified by an accrediting agency. Our community resource materials and tools span topics such as college accreditation, financial aid, opportunities available to veterans, people with disabilities, as well as online learning resources. We feature higher education institutions that have developed online learning programs that include highly trained faculty, new technology and resources, and online support services to help students achieve educational success.
Brammell B.F.,University of Kentucky |
Brammell B.F.,Asbury University |
Price D.J.,Lexington Fayette Urban County Government |
Elskus A.A.,University of Kentucky |
Elskus A.A.,University of Maine, United States
Comparative Biochemistry and Physiology - C Toxicology and Pharmacology | Year: 2013
Organisms chronically exposed to organic pollutants such as polychlorinated biphenyls (PCBs) can develop resistance to these chemicals, a condition associated with reduced inducibility of the biomarker enzyme cytochrome P450 1A (CYP1A). This study addresses the CYP1A response of members of the families Ictaluridae and Centrarchidae, two fish families found throughout much of the United States. We measured CYP1A expression, PCB body burdens, and conducted CYP1A challenge experiments in species from these families residing in the Town Branch/Mud River system (Logan County, KY, USA), a stream system historically contaminated with high levels of PCBs. Despite PCB concentrations in muscle tissue typically associated with elevated CYP1A (16.7 to 75.2 μg PCB/g wet edible flesh), resident fish in the contaminated Town Branch/Mud River sites (yellow bullhead [Ameiurus natalis], green sunfish [Lepomis cyanellus], and spotted bass [Micropterus punctulatus]) had hepatic CYP1A activity levels similar to, rather than higher than, those in reference fish, suggesting reduced sensitivity to CYP1A induction. Lack of CYP1A expression following direct contaminant exposure has often been associated with resistance to those contaminants. To determine if CYP1A in resident populations was resistant to induction by PCBs, we exposed resident fish to a single, intraperitoneal injection with a potent CYP1A inducer, 3,4,3′,4′-tetrachlorobiphenyl (PCB 77). PCB 77 treatment significantly induced hepatic CYP1A activity and protein in yellow bullhead from reference, but not contaminated, sites and had no effect on CYP1A in green sunfish from either site. The low CYP1A expression levels in resident fish with elevated PCB body burdens, together with the failure of PCB injection to induce CYP1A in certain populations, indicate an acclimatory CYP1A response in yellow bullheads and likely an inherently resistant CYP1A in green sunfish. This work demonstrates for the first time acclimation of CYP1A to PCBs in a species within the family Ictaluridae and provides further support for our previous work indicating an apparent inherent lack of CYP1A sensitivity to chlorinated inducers in Centrarchids. These traits may explain, at least in part, the common association of these families with degraded habitats and indicate Lepomis members are likely to be excellent candidates for exploring the mechanistic basis of 'inherent' CYP1A resistance. This study also underlines to the need for thorough characterization of the CYP1A responsivity of a population and/or species prior to using CYP1A as a reliable biomonitoring tool. © 2012 Elsevier Inc.
PubMed | Asbury University and Shanghai JiaoTong University
Type: Journal Article | Journal: Journal of materials chemistry. B, Materials for biology and medicine | Year: 2016
A multifunctional anti-cancer nanomedicine based on a biotin-poly(ethylene glycol)-poly(curcumin-dithio dipropionic acid) (Biotin-PEG-PCDA) polymeric nanocarrier loaded with paclitaxel (PTX), magnetic nanoparticles (MNPs) and quantum dots (QDs) is developed. It combines advantageous properties of efficient targeted delivery and uptake (
Self-assembled micelles of amphiphilic PEGylated rapamycin for loading paclitaxel and resisting multidrug resistant cancer cells†Electronic supplementary information (ESI) available: Chemicals and reagents, detailed experimental procedures for materials synthesis, characterization, cellular evaluations and supporting figures and tables See DOI: 101039/c4tb01633eClick here for additional data file
PubMed | Asbury University and Shanghai JiaoTong University
Type: Journal Article | Journal: Journal of materials chemistry. B, Materials for biology and medicine | Year: 2015
Self-assembled micelles of amphiphilic PEG-rapamycin conjugates loaded with paclitaxel have been developed for co-delivery and simultaneous intracellular release of paclitaxel and rapamycin, bypassing the cancer cell drug resistant mechanism and maximising the synergy of dual-drug combinational therapy. This novel nanomedicine offers 20-fold improved potency over free paclitaxel against a model multidrug resistant human breast cancer cell.
Veliz-Cuba A.,University of Nebraska - Lincoln |
Arthur J.,North Carolina State University |
Hochstetler L.,Asbury University |
Klomps V.,Northwestern College |
Korpi E.,University of Wisconsin - River Falls
Bulletin of Mathematical Biology | Year: 2012
For many biological systems that have been modeled using continuous and discrete models, it has been shown that such models have similar dynamical properties. In this paper, we prove that this happens in more general cases. We show that under some conditions there is a bijection between the steady states of continuous and discrete models arising from biological systems. Our results also provide a novel method to analyze certain classes of nonlinear models using discrete mathematics. © 2012 Society for Mathematical Biology.
Anigbogu C.N.,University of Lagos |
Anigbogu C.N.,University of Kentucky |
Speakman R.O.,University of Kentucky |
Silcox D.L.,University of Kentucky |
And 11 more authors.
Autonomic Neuroscience: Basic and Clinical | Year: 2012
We recorded arterial pressure (BP) and heart rate (HR) in type-1 diabetic rats vs. controls for > 6. months. Diabetic rats (DIAB) were maintained on insulin from the day glucose >250. mg/dl ("Day 0"). Weight was similar between groups until ~. 3. weeks before Day 0 when the weight in DIAB transiently lagged the controls (CONT); this difference was maintained throughout the study, but both groups otherwise gained weight in parallel. Plasma glucose attained 371 ± 109 (SD) mg/dl by day 1 in DIAB. Mean BP was similar across groups, and declined through the initial 4-6. months in both the CONT (at -0.06 ± 0.04. mm. Hg/day) and in the DIAB (at -0.14 ± 0.21. mm. Hg/day; NS vs. CONT). HR in the CONT (Month 1: 341 ± 13. bpm) exceeded DIAB (325 ± 25. bpm) through ~. 6. months after Day 0, and also decreased progressively over this period in CONT (-0.19 ± 0.14. bpm/day) and DIAB (-0.29 ± 0.23. bpm/day; NS vs. CONT) before leveling. The BP power within 0.35-0.45. Hz changed during the 90. min before vs. after the transition from dark to light, and light to dark; there were no between group differences. The slope of the log-log linear portion of the BP power spectrum between 1.0/h and 1/min was similar across groups, and increased in both from month 1 to month 6. Regulatory mechanisms maintain similar profiles in BP and HR in diabetic vs. control animals through the initial half year of the disease. © 2012 Elsevier B.V.
Randall D.C.,University of Kentucky |
Randall D.C.,Asbury University |
Speakman R.O.,University of Kentucky |
Silcox D.L.,University of Kentucky |
And 11 more authors.
Frontiers in Physiology | Year: 2011
We recorded via telemetry the arterial blood pressure (BP) and heart rate (HR) response to classical conditioning following the spontaneous onset of autoimmune diabetes in BBDP/Wor rats vs. age-matched, diabetes-resistant control (BBDR/Wor) rats. Our purpose was to evaluate the autonomic regulatory responses to an acute stress in a diabetic state of up to 12months duration. The stress was a 15-s pulsed tone (CS+) followed by a 0.5s tail shock.The initial, transient increase in BP (i.e., the "first component," or C1), known to be derived from an orienting response and produced by a sympathetic increase in peripheral resistance, was similar in diabetic and control rats through ~ 9months of diabetes; it was smaller in diabetic rats 10 months after diabetes onset. Weakening of the C1 BP increase in rats that were diabetic for >10 months is consistent with the effects of sympathetic neuropathy. A longer latency, smaller, but sustained "second component" (C 2) conditional increase in BP, that is acquired as a rat learns the association between CS+ and the shock, and which results from an increase in cardiac output, was smaller in the diabetic vs. control rats starting from the first month of diabetes. A concomitant HR slowing was also smaller in diabetic rats. The difference in the C 2 BP increase, as observed already during the first month of diabetes, is probably secondary to the effects of hyperglycemia upon myocardial metabolism and contractile function, but it may also result from effects on cognition. The small HR slowing concomitant with the C 2 pressor event is probably secondary to differences in baroreflex activation or function, though parasympathetic dysfunction may contribute later in the duration of diabetes.The nearly immediate deficit after disease onset in the C 2 response indicates that diabetes alters BP and HR responses to external challenges prior to the development of structural changes in the vasculature or autonomic nerves. © 2011 Randall, Speakman, Silcox, Brown, Brown, Gong, Patwardhan, Reynolds, Karounos, Burgessand Anigbogu.
Stoltzfus K.M.,LCC International University |
Cecil D.,Asbury University
Substance Use and Misuse | Year: 2013
This article explores the lived experiences of individuals who have participated in faith-based substance user rehabilitation programs in the Russian Federation. The Russian Federation has high rates of alcohol and opioid dependence and a dearth of professional treatment options. In the post-Soviet period, Evangelical Christian groups have developed substance user rehabilitation programs to attempt to address substance use and its related problems. Data were collected during 2010 via focus group interviews with participants in three Evangelical rehabilitation programs in the Volga region of the Russian Federation. Themes emerging from the qualitative data analysis process were classified into three broad categories: Typical Day, Personal Background/Decision to Enter Rehabilitation, and Helpful Aspects of Rehabilitation Process. © 2013 Informa Healthcare USA, Inc.
Pai V.P.,University of Cincinnati |
Pai V.P.,Tufts University |
Hernandez L.L.,University of Cincinnati |
Hernandez L.L.,University of Wisconsin - Madison |
And 2 more authors.
BioMed Research International | Year: 2015
Autocrine-paracrine activity of serotonin (5-hydroxytryptamine, 5-HT) is a crucial homeostatic parameter in mammary gland development during lactation and involution. Published studies suggested that the 5-HTreceptor type was important for mediating several effects of 5-HT in the mammary epithelium. Here, using 5-HTreceptor-null (HT7KO) mice we attempt to understand the role of this receptor in mediating 5-HT actions within the mammary gland. We demonstrate for the first time that HT7KO dams are inefficient at sustaining their pups. Histologically, the HT7KO mammary epithelium shows a significant deviation from the normal secretory epithelium in morphological architecture, reduced secretory vesicles, and numerous multinucleated epithelial cells with atypically displaced nuclei, during lactation. Mammary epithelial cells in HT7KO dams also display an inability to transition from lactation to involution as normally seen by transition from a columnar to a squamous cell configuration, along with alveolar cell apoptosis and cell shedding. Our results show that 5-HTis required for multiple actions of 5-HT in the mammary glands including core functions that contribute to changes in cell shape and cell turnover, as well as specialized secretory functions. Understanding these actions may provide new interventions to improve lactation performance and treat diseases such as mastitis and breast cancer. © 2015 Vaibhav P. Pai et al.
PubMed | University of Cincinnati, Asbury University, University of Wisconsin - Madison and Tufts University
Type: | Journal: BioMed research international | Year: 2015
Autocrine-paracrine activity of serotonin (5-hydroxytryptamine, 5-HT) is a crucial homeostatic parameter in mammary gland development during lactation and involution. Published studies suggested that the 5-HT7 receptor type was important for mediating several effects of 5-HT in the mammary epithelium. Here, using 5-HT7 receptor-null (HT7KO) mice we attempt to understand the role of this receptor in mediating 5-HT actions within the mammary gland. We demonstrate for the first time that HT7KO dams are inefficient at sustaining their pups. Histologically, the HT7KO mammary epithelium shows a significant deviation from the normal secretory epithelium in morphological architecture, reduced secretory vesicles, and numerous multinucleated epithelial cells with atypically displaced nuclei, during lactation. Mammary epithelial cells in HT7KO dams also display an inability to transition from lactation to involution as normally seen by transition from a columnar to a squamous cell configuration, along with alveolar cell apoptosis and cell shedding. Our results show that 5-HT7 is required for multiple actions of 5-HT in the mammary glands including core functions that contribute to changes in cell shape and cell turnover, as well as specialized secretory functions. Understanding these actions may provide new interventions to improve lactation performance and treat diseases such as mastitis and breast cancer.