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Fukuda K.,Asada General Hospital | Nakagawa Y.,National Hospital Organization
No To Hattatsu | Year: 2013

Objective: We investigated the relationship between the gross motor function and the causes of death and complications in persons with severe motor and intellectual disabilities (SMID). Methods:The causes of death, complications and ages of the 777 patients who had been admitted to the wards for persons with SMID in institutions involved in the national hospital organization and died from 1999 to 2008, were reported. Of these patients, 679 patients had data available. The patients were divided into 4 groups;group A (479 cases who could not roll over), group B (31 cases who could roll over but could not sit up), group C (53 cases who could sit up but could not stand up), and group D (22 cases who could stand up but could not walk without support). Results:The frequency of swallowing disturbance in group A was significantly higher than that in the other groups, while the frequency of gastroesophageal reflux was significantly lower in group C than in groups A and B. The percentage of tube feeding in group A was higher than that in the other groups. The differenc between groups A and C was statistically significant. The frequency of tracheotomy in group B was significantly lower than in group A and there were no cases of tracheotomy in groups C and D. Concerning the causes of death, the percentages of respiratory disorders in groups A, B, C, D were 52.4, 32.3, 35.8, 31.8, respectively. The mean age of death in group A was about 10 years younger than in the other groups. Conclusions:The gross motor function predicted the likelihood of respiratory and digestive systems complications and was related to life expectancy. Source

Mitani M.,Asada General Hospital | Miyamoto M.,Asada General Hospital | Tsuda H.,Asada General Hospital | Nishiwaki K.,Asada General Hospital | And 6 more authors.
Japanese Journal of Cancer and Chemotherapy | Year: 2014

Case: An 82-year-old man died because of squamous cell carcinoma of the right lung with metastasis to the left femoral bone. At the age of 75 years, he was admitted to our hospital because of hematemesis. Widespread type 3 gastric cancer was detected in the lesser curvature. Computed tomography (CT) showed multiple liver metastases. Preoperative chemotherapy with TS-1/cisplatin (CDDP) was administered. TS-1 was orally administered at 80 mg/body/day and CDDP was administered by intravenous infusion at 20 mg/body/day every week for 3 weeks and this was followed by a drug-free 2-week period as the first course. After the fourth course, gastrectomy was performed for the primary lesion and radiofrequency ablation (RFA) was performed for the liver metastases. The patient survived for more than 7 years with a complete response (CR) and died thereafter because of squamous cell carcinoma of the lung. Source

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