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NEW HAVEN, CT, United States

Patent
Artificial Cell Technologies, Inc. | Date: 2014-10-08

Multilayer films comprised of polypeptide epitopes and a toll-like receptor ligand. The multilayer films are capable of eliciting an immune response in a host upon administration to the host. The multilayer films can include at least one designed peptide that includes one or more polypeptide epitopes from a virus, bacteria, fungus or parasite.


Patent
Artificial Cell Technologies, Inc. | Date: 2015-05-22

Layer by layer (LBL) construction of products by tangential flow filtration (TFF), or the like, is described, including computer controlled automation of such procedure for production of a multilayer coated core.


Patent
Artificial Cell Technologies, Inc. | Date: 2010-04-05

Disclosed herein are polypeptide multilayer films wherein a therapeutic agent is covalently linked to a first layer polypeptide. An advantage of such attachment is that the linked therapeutic agent can be controllably released from the multilayer film into the environment of the film upon the addition of a suitable stimulus. An advantage of the disclosed films and methods is enablement of environmentally-stimulated release under specific conditions.


Patent
Artificial Cell Technologies, Inc. | Date: 2010-04-09

Disclosed herein are polypeptide multilayer films comprising a hybrid polypeptide comprising a first polypeptide segment and a second segment, the two segments being covalently joined by one or more non-peptidic linkages. The first segment comprises a polypeptide having a magnitude of net charge per residue of greater than or equal to 0.4, and a length of greater than or equal to about 12 amino acid residues. The second segment comprises a polypeptide or another polyelectrolyte.


Patent
Artificial Cell Technologies, Inc. | Date: 2013-03-14

Multilayer films comprise polypeptide epitopes from

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