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Brasília, Brazil

Santos V.M.D.,Armed Forces Hospital HFA | Santos V.M.D.,Catholic University of Brasilia | De Sa D.A.R.,Armed Forces Hospital HFA | De Oliveira E.R.N.C.,Armed Forces Hospital HFA | And 3 more authors.
Infezioni in Medicina

Thoracic disc herniations are commonly found in asymptomatic individuals, sometimes with genetic predisposition. Congenital fusions of cervical vertebrae occur in Klippel-Feil syndrome, which may be asymptomatic or cause compressive myelitis due to cervical instability or associated herniated discs. We report the case of a 72-year-old man with monophasic acute transverse myelitis probably caused by herpes simplex virus, coexistent with fused cervical vertebrae (C4-C5) and thoracic herniated discs. Establishment of the aetiology in cases of transverse acute myelitis can constitute a challenge in patients with cervical spine anomaly and disc herniations. Source

De Lima S.H.M.,Armed Forces Hospital HFA | Dos Santos V.M.,Catholic University of Brasilia | Dos Santos V.M.,Novo A/S | Daros A.C.,HRAS | And 2 more authors.
Journal of Medical Case Reports

Introduction. Giant cystadenocarcinomas of the ovary are rarely described conditions. Case presentation. The authors describe a 57-year-old Brazilian woman who presented with an increase in abdominal girth in February 2003. Imaging studies showed a giant abdominal pelvic mass with probable origin in the right ovary. Cancer antigen-125 was elevated, while carcinoembrionic antigen and alpha-fetoprotein were normal. Total abdominal hysterectomy, bilateral salpingoophorectomy and omentectomy were done. The mass weighed 40Kg, and the histopathology study revealed a mucinous cystadenocarcinoma. She underwent chemotherapy with paclitaxel and cisplatin with no side effects. Under follow-up for more than 10 years, she is asymptomatic and with normal imaging and laboratory parameters, including the cancer antigen-125 marker. Conclusion: This huge tumor evolved for a long time unsuspected and without metastases in a patient from a developing region. The diagnostic and management challenges posed by this unexpected and unusual presentation of an ovarian cystadenocarcinoma are discussed. © 2014de Lima et al.; licensee BioMed Central Ltd. ©2014 de Lima et al.; licensee BioMed Central Ltd. Source

dos Santos V.M.,Catholic University of Brasilia | Oliveira Camilo A.G.,Armed Forces Hospital HFA | de Souza L.A.,Armed Forces Hospital HFA | da Silva D.W.,Armed Forces Hospital HFA | And 2 more authors.
Acta Medica Iranica

We describe a 69-year-old-woman with antecedent of breast cancer and recent transitory neurological symptoms. Physical examination showed yellow to orange skin pigmentation, more conspicuous on her palms and soles, while discoloration changes were absent in the eye and oral mucous membranes. Routine laboratory findings were not indicative of hemolytic anemia, liver or bile disorders, nephrotic syndrome, hypothyroidism or diabetes mellitus. We emphasize the role of her excessive ingestion of papaw and tomato. These foods are rich in carotenoids (β-carotene and lycopene), which are associated with pigmentation disorders. The skin discoloration improved in about two months after correction of the inadequate diet. Major concerns about differential diagnosis of yellow skin pigmentation are also highlighted. © 2013 Tehran University of Medical Sciences. All rights reserved. Source

Dos Santos V.M.,Catholic University of Brasilia | Dos Santos V.M.,Novo A/S | Teles L.T.,Armed Forces Hospital HFA | Leao C.E.S.,Armed Forces Hospital HFA | And 3 more authors.
Indian Journal of Sexually Transmitted Diseases

We report a case of recurrent deep venous thrombosis in a 44-year-old woman, intravenous drug user and HIV-infected, who injected cocaine in the groins and veins of the dorsum of the feet. She suffered several episodes of deep venous thrombosis and soft-tissue infections in the lower limbs. Images of Doppler ultrasound scan revealed thrombosis in the right popliteal vein with partial recanalization and calcified thrombi in the territory of the right femoral vein. After use of heparin and oral anticoagulation, her clinical evolution was uneventful, and she was asymptomatic at the occasion of the hospital discharge. This report calls for better awareness about injections in the groins and superficial femoral veins, which are part of the deep venous system. Thrombosis related to HIV infection is highlighted. Source

Furtado W.S.,Armed Forces Hospital HFA | dos Santos V.M.,Pontifical Catholic University of Rio de Janeiro | Abdul Hak J.E.,Armed Forces Hospital HFA | Segura M.E.A.,Pathology Division from HFA
Cancer Therapy

We describe a 46-year-old female presenting with epigastric pain, anorexia and vomiting. Complementary evaluation revealed splenomegaly and esophageal varix, enlarged abdominal lymph nodes and low platelets. Splenectomy was performed by laparotomy, and biopsy samples were obtained from adrenal, liver and lymph nodes. Furthermore, bone marrow puncture was performed. Histopathology study of all the samples showed cell infiltrates with classical features of sea-blue histiocytosis. Moreover, immunohistochemical analyses of the red pulp displayed typical findings of splenic littoral cell angioma, a rare tumor that has been associated with malignant, congenital, or immunological disorders. Sea-blue histiocytosis is an uncommon disorder, with not well-known pathogenesis. Further studies are required to clear the relationship of the angioma with this condition. The patient became asymptomatic soon after splenectomy, and has been in a good health during five years. One may hypothesize that littoral cell angioma would be the basic disease, with secondary sea-blue histiocytosis. Association of these uncommon entities was not previously reported. Source

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