Kyoto, Japan
Kyoto, Japan

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Patent
ARKRAY Inc. | Date: 2016-03-23

A method for treating a blood specimen with which capturing rates for both a small rare cell and a rare cell having a high deformability can be improved in the case where rare cells are contained in a blood specimen. The method for isolating or detecting a rare cell includes treating a blood specimen using a filter to isolate or detect a rare cell in the blood specimen.


Patent
ARKRAY Inc., Ultizyme International Ltd. and Tanaka Kikinzoku Kogyo K.K. | Date: 2016-08-09

A measuring method of measuring a concentration of a target ingredient in a sample by using a sensor including an interdigitated array electrode that includes a first electrode and a second electrode, and a reagent layer on the interdigitated array electrode, the measuring method includes: applying a voltage to between the first electrode and the second electrode; measuring a first current value of an electric current flowing between the first electrode and the second electrode; measuring a second current value of the current flowing between the first electrode and the second electrode; calculating the concentration of the target ingredient in the sample, based on a third current value; calculating a correction value, based on the first current value and the second current value; and a step of correcting the concentration of the target ingredient in the sample, based on the correction value.


Patent
ARKRAY Inc. and Ultizyme International Ltd. | Date: 2017-05-03

The present invention provides a mutant-type glucose dehydrogenase having glucose dehydrogenase activity and having decreased reactivity with xylose, wherein said mutant-type glucose dehydrogenase comprises a mutant-type -subunit comprising an amino acid sequence of 520 to 550 amino acids containing the following peptide sequences (i) to (v) in this order, except that one or more amino acid residue(s) selected from the group consisting of the glycine at position 10 in the peptide sequence (iii), the histidine at position 4 in the peptide sequence (iv), and the asparagine at position 4 in the peptide sequence (v) is/are substituted with another/other amino acid(s):(i) Val/Ile Val/Ile Val/Ile Gly Ser Gly Val Ala Gly (SEQ ID NO:21);(ii) Cys Cys Gly Asn Asn Asn Cys Met Pro Ile Cys (SEQ ID NO:22);(iii) Val Gly Arg Asn Leu Met Asp His Pro Gly Thr Gly (SEQ ID NO:23);(iv) Lys Lys Ile/Leu His Leu Ser Asn (SEQ ID NO:24);(v) Phe Ala Pro/Asn Asn Asn His Ile (SEQ ID NO:25).


Patent
ARKRAY Inc. and Ultizyme International Ltd. | Date: 2016-10-28

The present invention provides a mutant-type glucose dehydrogenase having glucose dehydrogenase activity and having decreased reactivity with xylose, wherein said mutant-type glucose dehydrogenase comprises a mutant-type -subunit comprising an amino acid sequence of 520 to 550 amino acids comprising an amino acid sequence of 520 to 550 amino acids comprising SEQ ID NO: 21, SEQ ID NO: 22, SEQ ID NO: 23, SEQ ID NO: 24 and SEQ ID NO: 25 in this order from N-terminus to C-terminus, except that one or more amino acid residue(s) selected from the group consisting of the glycine at position 10 in SEQ ID NO: 23, the histidine at position 4 in SEQ ID NO: 24, and the asparagine at position 4 in SEQ ID NO: 25 is/are substituted with another/other amino acid(s).


Patent
ARKRAY Inc. | Date: 2016-10-07

Provided is a blood measuring apparatus including: a spectroscope; an optical system configured to irradiate a living body with excitation light from a light source, and to guide, to the spectroscope, Raman scattered light from the living body; a control unit configured to adjust an irradiation position at which the living body is irradiated with the excitation light by the optical system; and a detector configured to detect a spectrum of the Raman scattered light using light of each wavelength dispersed by the spectroscope. A plurality of the spectra detected by the detector are integrated, and numerical value information regarding a substance included in blood of the living body is measured based on an integration result, and the control unit adjusts the irradiation position such that the plurality of spectra are detected at changed positions.


Patent
ARKRAY Inc. | Date: 2017-05-03

Provided is a blood measuring apparatus including: a spectroscope (1); an optical system (2) configured to irradiate a living body with excitation light from a light source (10), and to guide, to the spectroscope (1), Raman scattered light from the living body; a control unit (3) configured to adjust an irradiation position at which the living body is irradiated with the excitation light by the optical system (2); and a detector (4) configured to detect a spectrum of the Raman scattered light using light of each wavelength dispersed by the spectroscope (1). A plurality of the spectra detected by the detector (4) are integrated, and numerical value information regarding a substance included in blood of the living body is measured based on an integration result, and the control unit (3) adjusts the irradiation position such that the plurality of spectra are detected at changed positions.


A test result sheet creation device is provided with: a display unit which displays a test result of a saliva test, and a plurality of comment candidates corresponding to the test result; an input unit which accepts an input of the result of selection from the plurality of comment candidates; and a control unit which associates and stores, in a storage unit, at least one test result and a comment selected from the comment candidates, and creates a test result sheet including the at least one test result and the comment selected from the comment candidates.


An analytical tool is provided for analysis of a sample by capillary electrophoresis. The analytical tool includes an inlet reservoir (2) into which a sample is introduced, a capillary tube (4) in communication with the inlet reservoir (2), a filter (21) through which a liquid from the inlet reservoir (2) passes, an enlarged portion (61) undergoing a sudden increase in a cross-sectional area and being in communication with the inlet reservoir (2) and the capillary tube (4), and a pressure fluctuation reducer for preventing pressure fluctuation at the enlarge portion (61) from affecting a liquid in the capillary tube (4).


Patent
ARKRAY Inc. | Date: 2017-02-16

Disclosed is an information processing apparatus capable of communicating with a user terminal which acquires a first index value for reflecting a state of a first biological component of a user and evaluating a metabolic result of the first biological component in a certain period of time on the basis of the first biological component and which provides the acquired first index value to the user, wherein calibration curve data is delivered to the user terminal in order to use the calibration curve data for acquiring the first index value.


The present invention is intended to provide a new target component measurement method and a new target component measurement apparatus for measuring target components including glucose. The present invention provides a method for measuring a target component, including the following steps: applying a first voltage (V_(1)) to an electrode system in the presence of a sample, a redox catalyst to a target component, and an electron transfer substance; applying a second voltage (V_(2)) to the electrode system; and acquiring a signal by the electrode system in the second voltage application step, wherein the first voltage is a voltage equal to or higher than an oxidation potential (E) of the electron transfer substance, and the second voltage is a voltage lower than the oxidation potential (E) of the electron transfer substance.

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