Time filter

Source Type

Avivar Oyonarte C.,Area Integrada de Biotecnologia | Duran Salas I.,Area Integrada de Biotecnologia | Molina Arrebola M.A.,Area Integrada de Biotecnologia | Castilla Alcala J.A.,Area Integrada de Biotecnologia | And 2 more authors.
Revista del Laboratorio Clinico | Year: 2010

Introduction: Recent studies have demonstrated a possible decline in semen quality in men. One of the reasons for this is due, in part, to exogenous chemical substances, some of which have hormonal activity, and are considered to be endocrine-disrupting chemicals. Pesticides can be included in this group. Material and methods: These studies have been criticized both for errors in selecting the study group as well as for the analytical methods employed. The objective of our study is to evaluate the concentration of pesticides in blood samples-in addition to the sperm count and semen quality parameters (according to criteria set out by the W.H.O.) in a population of 273 healthy men with an average age of 20.7 years; all from Southern Spain and recruited in collaboration with the University of Almeria. Results: Out of the total of 224 serum samples available, at least one pesticide was quantified per sample, with an average of 11 pesticides per sample; the most frequent being p,p'-DDE, present in 95.98% of the samples. Only in the case of endosulfan sulphate (present in 45.1% of the volunteers) was there a strong reduction tendency in the number of spermatozoa of more than 1.23 million, reaching statistical significance(P=0.009), with a 95% confidence interval of -1.43 to -1.05. As far as the number of motile spermatozoa were concerned, it was also only with endosulfan sulphate that a statistically significant reduction of 1.23 million (P=0.02) in the total number appeared, with a 95% confidence interval of -1.47 to -1.04). © 2009 AEBM, AEFA y SEQC.

Discover hidden collaborations