Nordborg, Denmark
Nordborg, Denmark
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Patent
Applied Biomimetic | Date: 2017-07-19

A process for the generation of electricity comprises the steps of extracting a warm saline stream from a geothermal formation, and converting latent osmotic energy present in said stream into electricity by passage through an osmotic power unit in which said stream is passed over one side of a semi-permeable membrane which permits the passage of water but not the passage of salts, an aqueous stream of lower salinity than said stream being passed over the other side of said membrane. The temperature of said warm saline stream is reduced before said stream enters the osmotic power unit by passage through a thermal power unit in which thermal energy present in said stream is converted into electricity.


Patent
Applied Biomimetic | Date: 2017-02-01

Novel block copolymers comprising at least one (poly)2-C1-3alkyl-2-oxazoline block and at least one (poly)dimethyl siloxane block, having at least one end group X which includes both an -NH2 group and an -NH- group, have been found to be particularly suitable for forming vesicles. The vesicles may be used to form filtration membranes.


Patent
Applied Biomimetic | Date: 2017-02-01

The invention provides a filtration membrane which comprises a porous support and, covalently bonded to a surface thereof, a layer comprising a plurality of vesicles having transmembrane proteins incorporated therein, said vesicles being formed from an amphiphilic block copolymer; characterised in that within said layer, vesicles are covalently linked together to form a coherent mass. The membrane may be prepared by a process which comprises providing an aqueous suspension of vesicles having transmembrane proteins incorporated therein, said vesicles being formed from an amphiphilic block copolymer having reactive end groups; depositing said suspension of vesicles on a surface of a porous support; and providing reaction conditions such that covalent bonds are formed between different vesicles and between vesicles and said surface.


Patent
Applied Biomimetic | Date: 2015-03-24

Novel block copolymers comprising at least one (poly)2-C_(1-3)alkyl-2-oxazoline block and at least one (poly)dimethyl siloxane block, having at least one end group X which includes both an NH_(2 )group and an NH group, have been found to be particularly suitable for forming vesicles. The vesicles may be used to form filtration membranes.


Patent
Applied Biomimetic | Date: 2015-03-24

The invention provides a filtration membrane which comprises a porous support and, covalently bonded to a surface thereof, a layer comprising a plurality of vesicles having transmembrane proteins incorporated therein, said vesicles being formed from an amphiphilic block copolymer; characterised in that within said layer, vesicles are covalently linked together to form a coherent mass. The membrane may be prepared by a process which comprises providing an aqueous suspension of vesicles having trans membrane proteins incorporated therein, said vesicles being formed from an amphiphilic block copolymer having reactive end groups; depositing said suspension of vesicles on a surface of a porous support; and providing reaction conditions such that covalent bonds are formed between different vesicles and between vesicles and said surface.


Lai H.,Hubei University | Xiao Y.,Hubei University | Yan S.,Hubei University | Tian F.,Hubei University | And 6 more authors.
Analyst | Year: 2014

In this study, we present a fluorescent switch-on probe based on a cyanovinyl-pyridinium triphenylamine (CPT) derivative that exhibited a 190-fold increase in fluorescence upon binding to G-quadruplex-forming oligonucleotide 22AG. This probe showed specificity and selectivity towards an antiparallel G-quadruplex, indicating its promising potential in G-quadruplex imaging. © 2014 the Partner Organisations.


Grzelakowski M.,Applied Biomimetic | Kita-Tokarczyk K.,Applied Biomimetic
Nanoscale | Year: 2016

The terminal groups of amphiphilic block copolymers are shown to control macromolecular self-assembly in aqueous solutions, in the micellar/lamellar region of the phase diagram. At the same concentration and using the same self-assembly conditions, dramatic differences are observed in polymer hydration and the resulting nano-/microstructure for two series of polymers with identical block chemistry and hydrophilic-lipophilic balance (HLB). This suggests a strong contribution from end groups to the hydration as the initial step of the self-assembly process, and could be conveniently used to guide the particle morphology and size. Additionally, for polymers with those head groups which drive vesicular structures, differences in membrane organization affect their physical properties, such as permeability. © The Royal Society of Chemistry 2016.


Grzelakowski M.,Applied Biomimetic | Cherenet M.F.,Applied Biomimetic | Shen Y.-X.,Pennsylvania State University | Kumar M.,Pennsylvania State University
Journal of Membrane Science | Year: 2015

Aquaporin based membranes (ABMs) are considered a promising biomimetic desalination technology and have been intensively studied over the last few years. The most common strategy to synthesize ABMs is to deposit the aquaporin incorporated lipid or block copolymer (BCP) vesicles onto porous substrates or more recently to integrate them within the active layer of polyamide membranes. However, ABMs with orders of magnitude improvement in permeability and perfect salt rejections proposed in initial work have not been realized. Early results were based on materials and methods that were rudimentary, especially considering the progress that has been made in this field. In particular, low signal to noise ratios (SNRs <50) of stopped flow measurements for vesicle-based assays have led to large inaccuracies in permeability estimation. We show that such low SNRs can result from using vesicle samples with a high concentration of micelles and provide a connection between morphology and data quality. We have conducted a comprehensive evaluation of the true promise of these membranes using improved methods for polymer synthesis, self-assembly, experimental evaluation as well as calculations that more directly compare the outcome of biophysical evaluations to those used in the desalination membrane industry. We propose these as standard methods for use in ABM research. The role of concentration polarization in introducing error into vesicle based permeability measurements is identified. We further describe a simple technique to calculate the expected flux from a membrane synthesized using vesicle immobilization on a permeable substrate that can be used to estimate realistic membrane fluxes from stopped flow data. These calculations show that it is possible to achieve permeabilities one to two orders of magnitude higher than current membranes using ABMs but several innovations will be needed to reach this potential. © 2015 Elsevier B.V.


Trademark
Applied Biomimetic | Date: 2016-09-30

Turbines for power generation; generators of electricity; membrane filters for use as part of machines. Apparatus and instruments for accumulating and storing energy; Apparatus, instruments and installations for osmotic generation of power from geothermal wells; inverters; controls for use in connection with generation of power; surveillance equipment in connection with generation of power; software; membranes for filtration for scientific use. Water filtration apparatus; membranes for the filtration of water; reverse osmosis water filtration equipment. Commercial advisory services relating to exploitation of osmotic power generation. Energy production; rental of energy production equipment; generation of power; production of electrical power from renewable sources. Scientific and technological services; research and development in connection with energy production and generation of power; consultancy relating to membrane technology; consultancy relating to osmosis technology; consultancy relating to CO2 reduction and renewable energy; design and development of production equipment for renewable energy production.


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