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Mukhamedzhanov E.K.,Anti infective Drugs Research Center | Esyrev O.V.,Anti infective Drugs Research Center
Diabetes Mellitus | Year: 2013

In this paper, we present a model of interplay between protein, lipid and carbohydrate metabolic pathways with regard to the carbon chain transporting systems, as well as generation and consumption of energy. This model elucidates the role of protein metabolism in the impairment of glucose tolerance during the absorption period. We also discuss the effects on energy homeostasis exercised by cytokines via mTOR pathway (the key factor of insulin signalling) considering the phenomenon of insulin resistance. Source

Il'in A.I.,Anti infective Drugs Research Center | Kulakov I.V.,Institute of Organic Synthesis | Leonova N.V.,Anti infective Drugs Research Center | Kasymbekova S.S.,Anti infective Drugs Research Center | And 2 more authors.
Russian Journal of General Chemistry | Year: 2011

Reactions of (N-1-methylglucosaminocarbonothioyl)-4-bromobenzamide with copper(II) sulfate in the ratios 1:1 and 2:1 affords the corresponding chelate complexes of the metal. Their structure was proved by high resolution mass spectrometry. The complex of (N-1-methylglucosaminocarbonothioyl)-4- bromobenzamide with copper(II) sulfate (ratio 1:1) exhibits pronounced antibacterial activity. © Pleiades Publishing, Ltd., 2011. Source

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