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Chidambaram, India

Annamalai University is one of Asia's largest public residential universities located in Annamalai Nagar, Chidambaram, Tamil Nadu, India. The university is spread across 1,500 acres acres in Chidambaram and offers courses of higher education in science, engineering, humanities, agriculture and arts.The university also provides more than 500 courses through distance education. The Directorate of Distance Education of Annamalai University offers education to those people who are unable to attend the campus but who desire to study. It is credited with the largest enrollment in India and is well equipped with computers and other infrastructure, separate teaching faculty and administration, study centers, and computer training centers to serve its students. It was the first institution in India to offer postgraduate degree programmes in Applied Psychology, Physics, Chemistry, Zoology, Botany, Bioinformatics and Law through distance education. The Directorate of Distance Education also offers programmes in Fashion Design, Textile Design, Interior Design, Hotel Management and Catering Technology, Retail Management, Twinning, Health Science, a Commonwealth Youth Programme, Yoga, Music, Fire and Safety, Pharmaceutical and Taxation.All the programmes of study offered by the Directorate of Distance Education have the approval of the Distance Education Council, New Delhi. The Directorate introduced a B.Ed. Programme through distance education in 2008-09 with the approval of National Council for Teacher Education, New Delhi. Wikipedia.

Chlorophyllin (CHL), a water-soluble, semi-synthetic derivative of chlorophyll and ellagic acid (EA), a naturally occurring polyphenolic compound in berries, grapes, and nuts have been reported to exert anticancer effects in various human cancer cell lines and in animal tumour models. The present study was undertaken to examine the mechanism underlying chemoprevention and changes in gene expression pattern induced by dietary supplementation of chlorophyllin and ellagic acid in the 7,12-dimethylbenz[a]anthracene (DMBA)-induced hamster buccal pouch (HBP) carcinogenesis model by whole genome profiling using pangenomic microarrays. In hamsters painted with DMBA, the expression of 1,700 genes was found to be altered significantly relative to control. Dietary supplementation of chlorophyllin and ellagic acid modulated the expression profiles of 104 and 37 genes respectively. Microarray analysis also revealed changes in the expression of TGFβ receptors, NF-κB, cyclin D1, and matrix metalloproteinases (MMPs) that may play a crucial role in the transformation of the normal buccal pouch to a malignant phenotype. This gene expression signature was altered on treatment with chlorophyllin and ellagic acid. Our study has also revealed patterns of gene expression signature specific for chlorophyllin and ellagic acid exposure. Thus dietary chlorophyllin and ellagic acid that can reverse gene expression signature associated with carcinogenesis are novel candidates for cancer prevention and therapy. Source

Jothilakshmi S.,Annamalai University
Applied Soft Computing Journal | Year: 2014

Acoustic analysis is a noninvasive technique based on the digital processing of the speech signal. Acoustic analysis based techniques are an effective tool to support vocal and voice disease screening and especially in their early detection and diagnosis. Modern lifestyle has increased the risk of pathological voice problems. This work focuses on a robust, rapid and accurate system for automatic detection of normal and pathological speech and also to detect the type of pathology. This system employs non-invasive, inexpensive and fully automated measures of vocal tract characteristics and excitation information. Mel-frequency cepstral coefficients and linear prediction cepstral coefficients are used as acoustic features. The system uses Gaussian mixture model and hidden Markov model classifiers. Cerebral palsy, dysarthria, hearing impairments, laryngectomy, mental retardation, left side paralysis, quadriparesis, stammering, stroke, tumour in vocal tract are the types of pathologies considered in our experiments. From the experimental results, it is observed that to classify normal and pathological voice hidden Markov model with mel frequency cepstral coefficients with delta and acceleration coefficients is giving 94.44% efficiency. Likewise to identify the type of pathology Gaussian mixture model with mel frequency cepstral coefficients with delta and acceleration coefficients is giving 95.74% efficiency. © 2014 Elsevier B.V. Source

Since ancient times, plant and microbial products were used in various aspects. However, their use against insects decreased when chemical products became developed. Recently, concerns increased with respect to public health and environmental security requiring detection of natural products that may be used against insects. In this study, mosquito Larvicidal and ovicidal activity of crude hexane, ethyl acetate, benzene, chloroform, and methanol extracts of the leaf of three plants, Eclipta alba, Cardiospermum halicacabum, and Andrographis paniculata, were tested against the early third-instar larvae of Anopheles stephensi (Liston) (Diptera: Culicidae). The larval mortality was observed after 24 h of exposure. All extracts showed moderate larvicidal effects; however, the highest larval mortality was found in methanol extract of A. paniculata, E. alba, and C. halicacabum against the larvae of A. stephensi (LC50 = 79.68, 112.56, and 133.01 ppm; LC90 = 154.66, 220.68, and 270.72 ppm), respectively. Mean percent hatchability of the ovicidal activity was observed 48 h post-treatment. The percent hatchability was inversely proportional to the concentration of extract and directly proportional to the eggs. Mortality of 100% with methanol and ethyl acetate extract of A. paniculata and methanol extract of E. alba were exerted at 200 ppm and methanol and benzene extract of C. halicacabum exerted at 150 ppm. This is an ideal eco-friendly approach for the control of the malaria vector, A. stephensi. Therefore, this study provides first report on the larvicidal and ovicidal activities against malaria vector, A. stephensi of E. alba plant extracts. © 2010 Springer-Verlag. Source

Mn2doped ZnS nanoparticles have been prepared through the reverse micelles method using sodium bis (2ethylhexyl) sulfosuccinate (AOT) as a surfactant. The prepared particles were characterized by X-ray diffraction (XRD), transmission electron microscopy (TEM), Fourier transform infra-red spectrometer (FT-IR), UVvis spectrometry, photoluminescence (PL), electron spin resonance (ESR) and thermogravimetrydifferential scanning calorimetry (TGDSC). © 2011 Elsevier B.V. Source

Murugadoss G.,Annamalai University
Journal of Materials Science and Technology | Year: 2012

Different morphologies of undoped and transition metals (Mn, Co and Ni) doped one-dimensional (1D) ZnO nanocrystals were successfully synthesized by chemical method in an air atmosphere using polyvinylpyrrolidone (PVP) as a surfactant. The structure and optical properties were studied by scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray diffraction (XRD), thermal gravimetric analysis (TGA), ultraviolet visible (UV-vis) absorption spectra and photoluminescence (PL) spectra. The doped ZnO nanorods exhibited a blue-shifted band gap and enhanced ultraviolet (UV) emission. In addition defect related emission was observed for the doped ZnO. © 2012 The Chinese Society for Metals. Source

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