Ankara, Turkey
Ankara, Turkey

Ankara University is a public university in Ankara, the capital city of Turkey. It was the first higher education institution founded in the Turkish Republic.The university has about 40 vocational programs, 114 undergraduate programs and 110 graduate programs. In total it has about 264 programs. Wikipedia.

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Agency: European Commission | Branch: FP7 | Program: CSA-SA | Phase: SiS.2012.2.1.1-1 | Award Amount: 3.19M | Year: 2013

GENOVATE is an action-research project based on the implementation of Gender Equality Action Plans (GEAPs) in six European universities. It brings together a consortium with diverse experience with gender equality mainstreaming approaches, with varying institutional and disciplinary backgrounds and located in different national contexts. All, however, share common challenges for women engaged in research and all have identified three common areas for intervention: (i) recruitment, progression and research support; (ii) working environment, work-life balance and institutional culture, and finally, (iii) the increasingly important domain of standards and diversity in research excellence and innovation. Each partner university will address these areas through their individually tailored GEAPs that will build on existing structures and policies where relevant, or develop new systems and practices where appropriate. This contextualised approach will be supported by an ongoing knowledge-exchange system within the consortium and by ongoing participatory evaluation, both of which will maximise the shared learning of all partners at every step of the process. An ePortfolio system will allow individual experiences, challenges and thoughts to be documented and collated throughout the implementation process and this will inform the main deliverables of the projects: a social model of gender equality implementation and guidelines tailored to different actors and different contexts highlighting the issues, the challenges and the approaches that work. Dissemination of the outcomes will be shaped by a communications strategy for learning within the institutions, within national learning circles with key stakeholders and, internationally, through networking, media and publication activities. The long-term impact of the project will also be felt within the partner universities: the implementation of the GEAPs involves sustainability strategies for each institution to ensure that ther

Olgen S.,Ankara University
Mini-Reviews in Medicinal Chemistry | Year: 2013

Human immunodeficiency virus-1 (HIV-1) infections cause global health problems. Indole derivatives have been considered as one of the promising HIV inhibitors. Recent inventions have focused on substituted indole and azaindole derivatives that possess unique antiviral activities against HIV-1. In this review, the evaluation of recent advances in substituted indole and azaindole derivatives for the treatment or prevention of HIV-1 and acquired immune deficiency syndrome (AIDS) has been focused. In this respect, compounds having drug and bio-active properties, including their synthesis and pharmacologic properties have been reported. In addition, anti-HIV properties of compounds, the structural features of inhibitors, the current progress in terms of therapeutic interventions and the leading groups in the field are discussed. Moreover, clinical and ADME (Absorption, Distribution, Metabolism, Elimination) properties of some clinically important compounds such as BMS-378806, L-737126 and IDX899 are reported. © 2013 Bentham Science Publishers.

Suzen S.,Ankara University
Current Drug Delivery | Year: 2013

Recent studies suggest that overproduction of reactive oxygen and nitrogen species (ROS/RNS), lowered antioxidant defense of the body. Oxidative stress is damaging to DNA, lipids, proteins and many more vital macromolecules. Consequences of oxidative stress thought to contribute to the development of a wide range of diseases including Alzheimer's disease, Parkinson's disease, diabetes, rheumatoid arthritis, neurodegeneration in motor neuron diseases and many cancer types. Melatonin (MLT) is a powerful antioxidant with a particular role in the protection of nuclear and mitochondrial DNA. To find an improved antioxidant activity, developments of novel synthetic analogues are under investigation. These studies may offer a new progress and approach in antioxidant drug development as well as antioxidant chemistry. Therefore, we have been synthesizing novel MLT derivatives and investigating their antioxidant capacities. This review gives a brief knowledge about the MLT based analogue indole derivatives as potential antioxidants. © 2013 Bentham Science Publishers.

Yilmaz O.,Ankara University
Neural Computation | Year: 2015

This letter introduces a novel framework of reservoir computing that is capable of both connectionist machine intelligence and symbolic computation. A cellular automaton is used as the reservoir of dynamical systems. Input is randomly projected onto the initial conditions of automaton cells, and nonlinear computation is performed on the input via application of a rule in the automaton for a period of time. The evolution of the automaton creates a space-time volume of the automaton state space, and it is used as the reservoir. The proposed framework is shown to be capable of long-term memory, and it requires orders ofmagnitude less computation compared to echo state networks. As the focus of the letter, we suggest that binary reservoir feature vectors can be combined using Boolean operations as in hyperdimensional computing, paving a direct way for concept building and symbolic processing. To demonstrate the capability of the proposed system, we make analogies directly on image data by asking,What is the automobile of air?. © 2015 Massachusetts Institute of Technology.

Agency: European Commission | Branch: H2020 | Program: CSA | Phase: MSCA-NIGHT-2014 | Award Amount: 353.52K | Year: 2014

Through the project, it is aimed to show public that researchers are most likely with them. They work in a wide range of topic but the common base for all areas is scientific point of view. It is planned to organize an event including at least 200 different interactive scientific activities from wide range of scientific disciplines, opening universities laboratories to public, organizing number of meetings and workshops, conferences, edutainment facilities, seminars and entertainment activities related to science subjects, observing and discussing ideas of public about science and hot topics of their life related to science and EU. Strategy for the activities is including all faculties and related centres of the university to take part during the night for the activities and using all resources of the municipality. Science will be in everything (with 25 different scientific disciplines) at everywhere (in 210000m2 campus and live online broadcast), at every time (by showing that science is in daily life) and for everybody (by the activities designed for everybody, i.e. children, young adults, women, disadvantaged groups etc.) in Ankara at the event day. It is expected to have 30.000 attendees per one Researchers Night event during the day and night. Besides that, the event will be announced and will be made news by 2 national TV and radio channel to whole country and there will be online live broadcast whole day and night through internet. It is expected to reach 500.000 attendees through live broadcast and more than 10.000.000 people will be made aware of Researchers Night activities. Event will develop public recognition on researchers accessibility and having time at different activities with scientists will positively affect especially young people. Impact and results of the event will also be an opportunity to show the affect and results of partnership and collaboration of different sectors and provide new partnerships between different sectors.

Agency: European Commission | Branch: H2020 | Program: RIA | Phase: YOUNG-3-2015 | Award Amount: 2.50M | Year: 2016

The existing research and policy reports show that adult education policies and practices are designed and carried out in ways and using means which are not always appropriate to vulnerable minority groups. In the EduMAP Project the diversity of societal participation and the wide range of cultural contexts and communicative practices among learners will be acknowledged. In particular, the educational needs of young people with low levels of basic and functional literacy, with deficient language and cultural skills (foreign newcomers, ethnic minorities), those who have dropped out of school and those not in education or training due to handicap, are in the focus of the project. The main research question is: What policies and practices are needed in the field of adult education to include young adults at risk of social exclusion in active participatory citizenship in Europe? Through the implementation of six work packages, EduMAP will help European, national and local policymakers, educational authorities and educators to tailor adult education policies and practices to meet the needs of young adults with low levels of education or who are otherwise in a vulnerable position. The project will provide comprehensive analyses and practical insights on the efficacy of the European adult education system in preventing social exclusion and compile an inventory of successful initiatives and communicative practices in and outside the EU. Communicative ecologies in the field of adult education will be mapped and analysed, and the findings will be utilized to create innovative platforms for enhancing dialogue between the providers and potential users of educational initiatives. An IDSS will be developed for the use of policymakers and other stakeholders. The fundamental aim is to help policymakers and educational agencies to ensure that the young generations as a whole are able to acquire the skills needed to fully participate in European societies and the labour market.

Agency: European Commission | Branch: FP7 | Program: MC-IRSES | Phase: FP7-PEOPLE-2013-IRSES | Award Amount: 545.80K | Year: 2014

With the statics of a wealth of model systems in statistical and condensed-matter systems being relatively well understood, an increased effort in research in these fields is channelled towards the understanding of dynamical phenomena. This agenda is even more pressing as dynamic effects are of crucial importance for many experimentally observed and technologically important phenomena. In the first work package, we will use the concerted effort and abundant synergies of the globe-spanning team of research groups to study a wide range of dynamical phenomena in statistical and condensed-matter physics, ranging from magnetic systems, to model systems on complex networks, to complex electronic systems such as graphene, to applications in soft matter and bio-physics. The results and techniques are expected to boost the understanding of dynamical effects in the human model systems in work package 2 which, in turn, is expected to offer new perspectives on the description of the systems investigated here. Socio-economic systems are increasingly studied with tools borrowed from statistical and condensed-matter physics. The theory of complex networks, in particular, has undergone an exciting development and has now found applications in a wide range of fields, including transport problems in modeling traffic systems, disease spreading or models for modeling agents acting in online communities. In the second work package, researchers in the consortium will apply techniques harvested from the wide array of tools used in statistical and condensed-matter physics as exemplified in the work items collected in work package 1 to a range of socio-economic systems with a focus on traffic and public transport models as well as the modeling of human behavior via the proxy of massivley multiplayer online games.

Yurdaydin C.,Ankara University
Seminars in Liver Disease | Year: 2012

Chronic delta hepatitis (CDH) remains the most progressive form of chronic viral hepatitis and as such its successful treatment is important. However, in striking contrast to the situation in chronic hepatitis B and C, no new drugs for its treatment have been introduced in the recent past and interferons remain the only evidence-based effective treatment of CDH. However, results are far from optimal. Overall, around 25 to 30% of patients may have a sustained response after one year of conventional or pegylated interferon (Peg-INF) treatment and such treatment may favorably affect the natural history of the disease. The superiority of Peg-INF over its conventional form is possible, but has not been demonstrated in a clinical trial. Several unanswered questions remain in the context of INF treatment such as (1) the need for standardization of HDV-RNA quantitation, the most widely used surrogate marker of treatment efficacy; (2) validation of this treatment end point as an index of long-term containment of HDV; (3) optimal duration of treatment; (4) baseline and on-treatment parameters of treatment efficacy; and (5) development of new markers of treatment efficacy. Nucleos(t)ide analogs (NAs) have been widely tested in CDH, but they appear to be ineffective when used for a duration of up to 2 years. Combination treatment of NAs with INFs also proved to be disappointing. New approaches to treatment are hepatocyte entry inhibitors and prenylation inhibitors to be hopefully tested in human CDH in the not-too-distant future. Copyright © 2012 by Thieme Medical Publishers, Inc.

Bilgin S.S.,Ankara University
Journal of Bone and Joint Surgery - Series A | Year: 2012

Background: Treatment of proximal humeral bone loss resulting from tumor resection or frominfection following shoulder arthroplasty represents a reconstructive challenge. Shoulder arthrodesis is an appropriate salvage procedure but is associated with a high rate of complications. The purpose of this report is to describe the surgical technique and report the functional outcomes in a series of patients treated with shoulder arthrodesis using free vascularized fibular graft. Methods: Nine patients were included in this study. Two-stage reconstruction was performed in three patients with a methicillin-resistant Staphylococcus aureus infection following primary shoulder hemiarthroplasty. The remaining six patients had an aggressive or malignant tumor of the proximal aspect of the humerus, and tumor resection included the rotator cuff in all of these patients and the axillary nerve in three. All nine patients underwent shoulder arthrodesis using free vascularized fibular graft; eight patients had fixation with two plate-screw constructs, and one patient had fixation with only one plate and screws. Clinical and radiographic evaluation of all patients was performed at a mean of sixty months postoperatively. The Musculoskeletal Tumor Society (MSTS) function score and the Toronto Extremity Salvage Score (TESS) were used to assess overall function of the upper limb. Results: Mean active shoulder abduction and flexion were both 80° (range, 60° to 100°). All but one patient could bring the hand to the mouth. The mean MSTS function and TESS values were twenty-four of thirty and 82%, respectively, representing a good functional outcome. Two of nine patients had a major complication. Union and fibular hypertrophy were achieved in seven of the nine patients. Conclusions: Shoulder arthrodesis using free vascularized fibular graft with double plate fixation is a reliable salvage procedure in patients with major proximal humeral bone loss. Level of Evidence: Therapeutic Level IV. See Instructions for Authors for a complete description of levels of evidence. Copyright © 2012 by The Journal of Bone and Joint Surgery, Incorporated.

Balci S.,Ankara University
Optics Letters | Year: 2013

In this Letter, ultrastrong plasmon-exciton coupling in an Ag nanoprism-J-aggregate hybrid nanostructure is reported. A localized surface plasmon wavelength of Ag nanoprisms is tunable starting from 400 to 1100 nm. Because of the large electric field localization at the corners of the nanoprisms, the observed Rabi splitting energy is higher than the previously reported Rabi splitting energies using metal nanoparticles. A giant Rabi splitting energy of more than 400 meV corresponding to ∼19% of the j-band energy has been observed, thus indicating the ultrastrong coupling regime. The hybrid nanostructure of nanoprism-J-aggregate is easy to prepare in large quantities and it can be uniformly assembled on solid substrates. © 2013 Optical Society of America.

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