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Ankara, Turkey

Demirel F.,Ankara Child Diseases | Unal S.,Ankara Child Diseases | Cetin I.I.,Ankara Child Diseases | Esen I.,Ankara Child Diseases | Arasli A.,Ankara Child Diseases
Journal of Pediatric Endocrinology and Metabolism | Year: 2011

Diazoxide is the main therapeutic agent for persistent hyperinsulinemic hypoglycemia. Generally, it is tolerated well, but rarely it can cause severe life-threatening complications. We report a neonate who was treated with diazoxide for hyperinsulinemic hypoglycemia. On the 6th day of the treatment we observed sepsis-mimicking symptoms, mild pulmonary hypertension, and re-opening of the ductus arteriosus. All these findings resolved dramatically shortly after discontinuation of treatment. To our knowledge, this is the first reported case of re-opening of the ductus arteriosus due to diazoxide toxicity. © 2011 by Walter de Gruyter Berlin Boston. Source

Ikiz M.A.,Ankara Child Diseases | Yakut H.I.,Ankara Child Diseases | Kurt F.,Ankara Child Diseases | Sahin S.,Ankara Child Diseases | And 3 more authors.
Pediatric Emergency Care | Year: 2013

Hydrogen peroxide solutions are often used in daily life as a household disinfectant and in cosmetic products and are therefore a common source of intentional poisonings, especially for children. When ingested in small amounts, it may cause severe central nervous system damage as a result of arterial emboli like our case. The benefit of hyperbaric oxygen treatment in this situation is known, but the neurologic deficits of our case did not improve with this method and finally brain death occurred. This is may be related by the timing of treatment after the event. We would like to emphasize that every clinician must be aware of the dangers of hydrogen peroxide ingestion and hyperbaric oxygen treatment may be of benefit if it is performed immediately.© Copyright 2013 by Lippincott Williams & Wilkins. Source

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